Developing and validating SARS-CoV-2 assays for nonhuman primate surveillanceArticle Published on 2022-10-012022-11-15 Journal: Journal of medical primatology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Algorithm antibody antiviral antibodies assays center detect Developing diagnostic diagnostic testing algorithm. enzyme immunoassay Infection Laboratory multiplex NIH nine nucleocapsid over performed primate reactive Receptor binding domain RT-PCR SARS-CoV-2 SARS-COV-2 infection specificity Surveillance tested Viral RNA virus antigen [DOI] 10.1111/jmp.12604 PMC 바로가기
Breakthrough cases of Omicron and Delta variants of SARS-CoV-2 during the fifth wave in PakistanArticle Published on 2022-09-292022-11-16 Journal: Frontiers in Public Health [Category] SARS, 변종, 치료기술, [키워드] affected age analyzed Breakthrough infection coronavirus coronavirus in Pakistan COVID-19 COVID-19 Pakistan Delta delta variant Department effective fifth wave in Pakistan Gender genotyped individual K417N mutation majority men NIH occurred omicron Omicron and Delta variant P681R pandemic Patient PrimerDesign Randomly SARS-CoV-2 Science selected Sinopharm Sinovac SPSS Statistical Package subject the patient vaccinated individual vaccination Vaccine vaccine breakthrough cases. Vaccines variant Virology were used while women [DOI] 10.3389/fpubh.2022.987452 PMC 바로가기
Physical activity and academic achievement: an analysis of potential student- and school-level moderatorsArticle Published on 2022-08-302022-10-05 Journal: The international journal of behavioral nutrition and physical activity [Category] 임상, [키워드] Academic achievement Accelerometers Affect age Analysis baseline Characteristics children collected Course cross-sectional Effect Elementary students engage examined Factor Follow-up Gender GRADE grade 3 Grade 5 Grades Hispanic ethnicity Inconclusive indicated investigated moderate NIH outcomes physical activity proportion recruited Registered Research School Schools socioeconomic status statistically significant student unique while [DOI] 10.1186/s12966-022-01348-3 PMC 바로가기 [Article Type] Article
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC studyResearch article Published on 2022-08-092022-10-05 Journal: EBioMedicine [Category] SARS, 바이오마커, 치료기술, [키워드] 7-point ordinal scale 95% CI age antibody assessment association baseline Better characteristics of patient chest imaging Cohort Comorbidities coronavirus disease COVID-19 creatinine death demographics discharge disease course disease severity Dyspnea elevated Factor female finding Follow-up funding Hispanic ethnicity hospital Hospitalization Hospitalized hospitalized COVID-19 Immunophenotyping IMPROVE integration interquartile range Invasive mechanical ventilation Laboratory Logistic regression longitudinal lowest lymphopenia management median age NIH Odds ratio offer outcome overall mortality PASC Patient PCR cycle provide Radiographic required Respiratory illness Result risk factor SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 PCR SARS-CoV2 serology severity Sex survivor Symptom Symptomatic patients The United States threshold Trajectories trajectory Unsupervised clustering Viral load was performed [DOI] 10.1016/j.ebiom.2022.104208 [Article Type] Research article
Prevention and treatment of COVID-19 in patients with benign and malignant blood disordersReview article Published on 2022-08-012022-10-05 Journal: Best Practice & Research Clinical Haematology [Category] 변종, 치료법, 치료제, [키워드] B-cell Blood Blood cancer Cell chimeric antigen receptor Community complications COVID-19 COVID-19 in patient disease disorder hematologic Hemoglobinopathies high risk immunization immunosuppressed patient Immunosuppression initial lymphoid malignancies malignancy moderate NIH pathology Patient prevention receive regimen risk Safe SARS-CoV-2 severe immunosuppression T-cell Therapies therapy threshold Treatment Vaccine while [DOI] 10.1016/j.beha.2022.101375 [Article Type] Review article
Considering innate immune responses in SARS-CoV-2 infection and COVID-19SARS-CoV-2 감염 및 COVID-19에서 선천 면역 반응 고려Article Published on 2022-08-012022-09-12 Journal: Nature reviews. Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘, 진단, 치료법, 치료제, [키워드] adaptive antibody COVID-19 COVID-19 pandemic Immunity Impact innate immune response innate immune system media memory T cells Nature NIAID NIH organized Program Ralph review SARS-COV-2 infection thought [DOI] 10.1038/s41577-022-00744-x PMC 바로가기 [Article Type] Article
Recruitment of pregnant women to randomised trials of COVID 19 treatments, and pharmaceutical treatments received outside such trials: A research articleCOVID 19 치료법의 무작위 시험에 임산부 모집 및 그러한 시험 이외의 약물 치료: 연구 기사Article Published on 2022-08-012022-09-11 Journal: European journal of obstetrics, gynecology, and re [Category] 임상, 치료법, 치료제, [키워드] Administered administration Case report case reports Case series case sery clinical trial registry controlled trials COVID 19 COVID-19 COVID-19 pandemic de-duplication duplication early phase eligible enrolled excluded identify information NIH observational studies participated Pregnancy pregnant women randomised Randomised trial randomised trials Randomized controlled trials recommendations registries reported Research searched Seven systematic review Treatment Trial trials with COVID-19 women [DOI] 10.1016/j.ejogrb.2022.05.009 PMC 바로가기 [Article Type] Article
Multisystem Inflammatory Syndrome Associated With COVID-19 in Children (MIS-C): A Systematic Review of Studies From India어린이의 COVID-19와 관련된 다기관 염증 증후군(MIS-C): 인도 연구의 체계적인 검토Article Published on 2022-07-152022-09-11 Journal: Indian pediatrics [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Admissions age article calculate children clinical Clinical features coronavirus disease Coronavirus disease 2019 Corticosteroid Corticosteroids Course COVID-19 database databases derangement disease course disease status Effect feature Features Fever Frequency Future gastrointestinal problem gastrointestinal problems GraphPad GraphPad software Health Organization Immunoglobulin India Inflammatory Inflammatory marker inflammatory markers intensive care Intravenous immunoglobulin IQR Kawasaki disease laboratory parameter Laboratory parameters majority male median MIS-C mortality rate NIH parameter Patient patients ranged reported required review SARS-COV-2 infection Screening Standard deviation syndrome systematic review the disease the mean Therapeutics Treatment was done was used World Health Organization [DOI] 10.1007/s13312-022-2559-5 PMC 바로가기 [Article Type] Article
Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trialClinical Trial Published on 2022-07-082022-10-05 Journal: The Lancet. Respiratory Medicine [Category] 임상, 진단, 치료법, [키워드] 1:1 addition adverse event Analysis assigned baseline Cohort Complete COVID-19 cumulative defined double-blind Europe extracorporeal membrane oxygenation finding Follow-up funding hazard ratio hospital discharge hospitalised hypothesised IMPROVE incidence infused intravenous Invasive mechanical ventilation investigators modified intention-to-treat monoclonal antibody combination Mortality neutralising NIH occurred operation Organ failure outcome participant Patient Phase 3 phase 3 trial Placebo placebo group placebo-controlled trial Primary outcome randomised Randomly receive receiving Registered Remdesivir renal replacement therapy Result Safe seronegative Singapore speed standard care study drug Study participants Support sustained Symptom the placebo group therapy Treatment Uganda USA were excluded with COVID-19 [DOI] 10.1016/S2213-2600(22)00215-6 [Article Type] Clinical Trial
Anti-nucleocapsid antibody levels and pulmonary comorbid conditions are linked to post-COVID-19 syndrome항뉴클레오캡시드 항체 수준 및 폐 동반질환 상태는 코로나19 이후 증후군과 관련이 있습니다Article Published on 2022-07-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] age allergy antibody Antigen Asthma Asymptomatic Biohub Biomarker Biomarkers blood draw blood draws center Cohort comorbid condition COVID-19 disease COVID-19 disease severity COVID-19 infections Critical CTSA Diagnosis disease disease severity Ethnic groups Ethnicity Factor foundation IgG IgG response immunoglobulins in-person visit Infectious disease initial initiative Lung disease median time nasal swab NIH not affect nucleocapsid IgG participant Patient PCR test PCR-positive positive RT-PCR ranged recruited Remdesivir reported reverse transcription risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid Sean Sex Stanford Stanford University Study participants sustained Symptom symptom resolution Symptoms syndrome with COVID-19 [DOI] 10.1172/jci.insight.156713 PMC 바로가기 [Article Type] Article