The anti-COVID-19 drug nirmatrelvir crosses the blood‒brain barrier and exhibits herb–drug pharmacokinetic interactions with Scutellaria baicalensis formulationsResearch Article Published on 2024-07-202024-09-05 Journal: Heliyon [Category] update2024, [키워드] Herb–drug interaction Microdialysis Nirmatrelvir NRICM101 pharmacokinetics [DOI] 10.1016/j.heliyon.2024.e34820 PMC 바로가기 [Article Type] Research Article
Development of robust antiviral assays using relevant apical-out human airway organoidsArticle Published on 2024-07-122024-09-05 Journal: bioRxiv [Category] update2024, [키워드] Antiviral testing apical-out AT-511 High-throughput Nirmatrelvir Organoid Remdesivir SARS-CoV-2 Standardization [DOI] 10.1101/2024.01.02.573939 PMC 바로가기 [Article Type] Article
In Silico Comparative Analysis of Ivermectin and Nirmatrelvir Inhibitors Interacting with the SARS-CoV-2 Main ProteaseArticle Published on 2024-06-252024-09-05 Journal: Biomolecules [Category] update2024, [키워드] Ivermectin main protease (Mpro) molecular docking molecular dynamics Nirmatrelvir SARS-CoV-2 [DOI] 10.3390/biom14070755 PMC 바로가기 [Article Type] Article
The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in severe models of COVID-19Article Published on 2024-06-142024-09-05 Journal: bioRxiv [Category] update2024, [키워드] COVID-19 Immunocompromised intra-host evolution molnupiravir Nirmatrelvir Paxlovid SARS-CoV-2 [DOI] 10.1101/2024.02.27.582110 PMC 바로가기 [Article Type] Article
Simultaneous measurement of COVID-19 treatment drugs (nirmatrelvir and ritonavir) in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic studyResearch Article Published on 2024-05-302024-09-05 Journal: Heliyon [Category] update2024, [키워드] Nirmatrelvir pharmacokinetics RAT Ritonavir UPLC-MS/MS [DOI] 10.1016/j.heliyon.2024.e32187 PMC 바로가기 [Article Type] Research Article
Antiviral Use in Mild-to-Moderate SARS-CoV-2 Infections during the Omicron Wave in Geriatric PatientsArticle Published on 2024-05-282024-09-05 Journal: Viruses [Category] update2024, [키워드] COVID-19 Geriatrics Nirmatrelvir Remdesivir Ritonavir [DOI] 10.3390/v16060864 PMC 바로가기 [Article Type] Article
Determining and Comparing the Real-World Effectiveness of Molnupiravir and Nirmatrelvir-Ritonavir in Patients Hospitalized With COVID-19Original Article Infectious Diseases Published on 2024-02-192024-09-05 Journal: Journal of Korean medical science [Category] update2024, [키워드] COVID-19 COVID-19 drug treatment molnupiravir Nirmatrelvir [DOI] 10.3346/jkms.2024.39.e52 PMC 바로가기 [Article Type] Original Article Infectious Diseases
Effectiveness of Vaccines and Antiviral Drugs in Preventing Severe and Fatal COVID-19, Hong KongResearch Published on 2024-01-012024-09-05 Journal: Emerging Infectious Diseases [Category] update2024, [키워드] Comirnaty CoronaVac coronavirus coronavirus disease COVID-19 Hong Kong molnupiravir Nirmatrelvir respiratory infections Ritonavir SARS SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 viruses zoonoses [DOI] 10.3201/eid3001.230414 PMC 바로가기 [Article Type] Research
Persistence of an infectious form of SARS-CoV-2 post protease inhibitor treatment of permissive cells in vitroArticle Published on 2023-12-212024-09-05 Journal: bioRxiv [Category] update2024, [키워드] decay Nirmatrelvir Protease inhibitor rebound SARS-CoV-2 Virus persistence [DOI] 10.1101/2023.12.20.572655 PMC 바로가기 [Article Type] Article
Optimizing COVID-19 treatment in immunocompromised patients: early combination therapy with remdesivir, nirmatrelvir/ritonavir and sotrovimabarticle Published on 2023-12-152024-09-05 Journal: Virology Journal [Category] update2024, [키워드] COVID-19 Immunocompromised Nirmatrelvir Remdesivir Sotrovimab [DOI] 10.1186/s12985-023-02269-8 PMC 바로가기 [Article Type] article