RAC1 nitration at Y 32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury지질다당류 매개 급성 폐 손상과 관련된 내피 장벽 파괴에 관여하는 Y 32 IS에서의 RAC1 니트로화Article Published on 2021-01-012022-09-11 Journal: Redox Biology [Category] SARS, 유전자 메커니즘, 진단, [키워드] Activation acute lung injury alveolar approach attenuate contractile COVID-19 dependent on determine effective therapy endothelial Endothelial cell endothelial cells functional high mortality human lung identify increase induce inhibitor involved junction lipopolysaccharide Local LPS lung Lung function Lung inflammation Lung injury mass spectrometry mechanism molecular murine model Nitration nucleotide peptide phenotype prevented pulmonary inflammation Rac1 Rac1. reduce reduced Rho GTPase Rho GTPases RHOA Sepsis severe pneumonia shielding shown switch systemic inflammation therapeutic target tyrosine vascular permeability [DOI] 10.1016/j.redox.2020.101794 PMC 바로가기 [Article Type] Article
Recent Advances in the Synthesis and Development of Nitroaromatics as Anti-Infective Drugsarticle Published on 2020-12-312024-09-01 Journal: Current Pharmaceutical Design [Category] 말라리아, [키워드] Infectious diseases Nitration nitroaromatic nitrofuran nitroimidazole nitrophenyl [Article Type] article