Guidelines for mitochondrial RNA analysisReview Published on 2024-06-262024-09-05 Journal: Molecular Therapy. Nucleic Acids [Category] update2024, [키워드] Gene Expression guidelines MicroRNAs Mitochondria MT: Non-coding RNAs Noncoding RNAs [DOI] 10.1016/j.omtn.2024.102262 PMC 바로가기 [Article Type] Review
Non-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significancearticle Published on 2023-09-132024-09-05 Journal: Journal of Translational Medicine [Category] update2024, [키워드] Cancer DNMT3B Noncoding RNAs [DOI] 10.1186/s12967-023-04510-y PMC 바로가기 [Article Type] article
Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disordersReview Published on 2023-06-212024-09-05 Journal: Cardiovascular Research [Category] update2024, [키워드] Biomarker ceRNA circRNA lncRNA miRNA Noncoding RNAs Polyadenylation Protein modification RNA-binding proteins Signalling splicing [DOI] 10.1093/cvr/cvad046 PMC 바로가기 [Article Type] Review
BioAutoML: automated feature engineering and metalearning to predict noncoding RNAs in bacteriaBioAutoML: 박테리아의 비코딩 RNA를 예측하기 위한 자동화된 기능 엔지니어링 및 금속 학습Article Published on 2022-07-182022-09-11 Journal: Briefings in Bioinformatics [Category] Coronavirus, 유전자 메커니즘, [키워드] accelerate Algorithm Algorithms Analysis approach automated automatically Bacteria benefit bioinformatics Care category components coronavirus disease Coronavirus disease 2019 coronavirus vaccine CRISPR develop Diseases domain Drug discovery Economy eight evaluate experimental results extraction feature Feature selection Features Health Health care helping housekeeping information knowledge machine learning mechanism ncRNA ncRNAs noncoding RNA Noncoding RNAs Precision predict Predictive Quantitative recent RECIPE reducing Regulatory selected sequence time-consuming translated tuning [DOI] 10.1093/bib/bbac218 PMC 바로가기 [Article Type] Article
Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccinationArticle Published on 2022-02-012022-11-16 Journal: Pharmacology & therapeutics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] addition Alter Antisense oligonucleotide approved aptamer ASO authorization BNT162b2 cell membrane Characteristics cross Degradation demonstrated develop Diseases drug eight Emergency expression FDA feasibility food function functional Genome gRNA IMPROVE interactions mechanism medication medications miRNA modulate molecular mRNA mRNA vaccine mRNA-1273 Noncoding RNAs pharmacological prevention of COVID-19 Protein public health Research RNA RNAs siRNA siRNAs Small molecules target gene the United State therapeutic therapeutic target Therapies therapy unique vaccination Vaccine [DOI] 10.1016/j.pharmthera.2021.107967 PMC 바로가기
SARS-CoV-2, Cardiovascular Diseases, and Noncoding RNAs: A Connected TriadSARS-CoV-2, 심혈관 질환 및 비암호화 RNA: 연결된 삼합체Review Published on 2021-11-122022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome coronavirus adverse outcome affecting association cardiovascular cardiovascular disease cardiovascular diseases cardiovascular system caused characterized Comorbidity condition Connected Consequences coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients CVD Cytokines DNA dramatic increase drugs functional Gene Expression increase Infection Inflammatory cytokine Inflammatory cytokines Interaction mechanism mortality risk ncRNA ncRNAs noncoding RNA Noncoding RNAs Patient Perspective pharmacological Proteins Regulation respiratory respiratory impairment RNA RNA molecule RNA molecules SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity transcribed translated treat Viral viral infection [DOI] 10.3390/ijms222212243 PMC 바로가기 [Article Type] Review
N6-methyladenosine methyltransferases: functions, regulation, and clinical potentialReview Published on 2021-07-272022-10-29 Journal: Journal of Hematology & Oncology [Category] COVID-19, [키워드] Affect approach Cancer Chemotherapy complexes Drug discovery function functions highlight Immunotherapy m6A m6A methyltransferase methyltransferase Modification N6-methyladenosine Noncoding RNAs pathway Proteins Radiotherapy Regulation reported RNA RNAs stability targeted therapy therapy Therapy resistance Transcriptome translation widespread [DOI] 10.1186/s13045-021-01129-8 PMC 바로가기 [Article Type] Review
Whole-Transcriptome RNA Sequencing Reveals Significant Differentially Expressed mRNAs, miRNAs, and lncRNAs and Related Regulating Biological Pathways in the Peripheral Blood of COVID-19 Patients전체 전사체 RNA 시퀀싱은 COVID-19 환자의 말초 혈액에서 유의미하게 차별적으로 발현된 mRNA, miRNA, lncRNA 및 관련 조절 생물학적 경로를 나타냅니다Research Article Published on 2021-04-012022-09-10 Journal: Mediators of Inflammation [Category] MERS, SARS, 유전자 메커니즘, [키워드] “cytokine storm” acute respiratory syndrome acute respiratory syndrome coronavirus AKT1 Analysis Antigen antigen processing Biological biosynthetic characterized China coding collected competing control group controls coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID-19 sample COVID-19 samples CXCL8 cytokine cytokine production Cytokine storm cytotoxicity diagnostic biomarker Diagnostic biomarkers differentially expressed downregulated enrichment analysis excessive cytokine production FCGR2A Functional enrichment analyses Gene ontology glycogen ground-glass opacity healthy controls healthy donor healthy donors highlight hub genes indicated Inflammation Interaction involved leukocyte leukocytes lncRNA long noncoding RNA lung tissues lymphocyte Lymphocytes mechanism Messenger RNA messenger RNAs microRNA MicroRNAs Migration miRNA miRNAs mRNA mRNAs noncoding RNA Noncoding RNAs pandemic Pathogenesis peripheral Peripheral blood positive potential mechanism potential mechanisms PPI presenting protein-protein interaction Regulating Regulation Regulatory respiratory resulting RNA SARS-CoV-2 selected Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 signaling pathway Significant significantly STAT3 systemic inflammation T cell T cell activation target the healthy therapeutic tissue TLR2 TNFRSF1B upregulated [DOI] 10.1155/2021/6635925 PMC 바로가기 [Article Type] Research Article
Circular RNA–MicroRNA–MRNA interaction predictions in SARS-CoV-2 infectionSARS-CoV-2 감염에서 원형 RNA-MicroRNA-MRNA 상호작용 예측Article Published on 2021-03-172022-09-10 Journal: Journal of Integrative Bioinformatics [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Antiviral cellular processe circRNA Circular coronavirus defined differential expression expressed feature Gene regulation hairpins higher eukaryotes host–pathogen interactions human miRNA human miRNAs identify Infection Interaction investigated involved machine learning mechanism microRNA MicroRNAs miRNA miRNAs mRNA mRNAs noncoding RNA Noncoding RNAs organism predict Regulation respiratory RNA SARS-CoV-2 SARS-COV-2 infection secondary structures severe acute respiratory syndrome Coronavirus shown Viral viral mRNA viral mRNAs virus viruses [DOI] 10.1515/jib-2020-0047 PMC 바로가기 [Article Type] Article
The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID‐19Research Article Published on 2020-10-112022-10-31 Journal: Clinical and Translational Medicine [Category] COVID-19, [키워드] acute respiratory syndrome addition Analysis Biomarker Blood blood transcriptome Cell cell types coding comprehensive view coronavirus COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Critical defined Disease progression downstream expression function global pandemic Human immune system Hyperactivation Immune cell immune dysregulation immune regulator immune response Infection microRNA MicroRNAs miRNAs moderate mRNA mRNAs noncoding RNA Noncoding RNAs Pathogenesis Patient performed peripheral immune response Potential biomarker profile Result RNA SARS‐CoV‐2 Sequencing severe patients suggested T‐cell the disease therapeutic target therapeutic targets transcriptional transcriptome profile Whole blood [DOI] 10.1002/ctm2.200 PMC 바로가기 [Article Type] Research Article