Modeling resource allocation strategies for insecticide-treated bed nets to achieve malaria eradicationarticle Published on 2024-02-282024-09-01 Journal: eLife [Category] 말라리아, [키워드] Epidemiology eradication funding allocation global health malaria mathematical modeling None optimization [Article Type] article
Participation in the nationwide cervical cancer screening programme in Denmark during the COVID-19 pandemic: An observational studyEpidemiology and Global Health Published on 2023-01-202024-09-05 Journal: eLife [Category] update2024, [키워드] cervical cancer screening COVID-19 pandemic Epidemiology None [DOI] 10.7554/eLife.81522 PMC 바로가기 [Article Type] Epidemiology and Global Health
COVID-19 pandemic dynamics in South Africa and epidemiological characteristics of three variants of concern (Beta, Delta, and Omicron)남아프리카 공화국의 COVID-19 대유행 역학 및 세 가지 우려 변종(베타, 델타 및 오미크론)의 역학적 특성Article Published on 2022-08-092022-09-11 Journal: eLife [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition African Beta Characteristics coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 pandemic Delta disease driver epidemiological epidemiological data Epidemiology estimate global health help immune immune evasion independent Infection infection rate Model New coronavirus nine None Nonpharmaceutical interventions omicron pandemic parameter public health quantification Reinfection reinfection rate retrospective risk SARS-CoV-2 SARS-CoV-2 transmission severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 South South Africa trajectory Transmissibility vaccination variant variant of concern variants of concern VoC VOCs [DOI] 10.7554/eLife.78933 PMC 바로가기 [Article Type] Article
Social contact patterns and implications for infectious disease transmission – a systematic review and meta-analysis of contact surveysResearch Article Published on 2021-11-252022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] 24 hours affected age age and gender all age groups Analysis asked baseline carried caused Characteristics collected consequence Contact Contact surveys country COVID-19 pandemic Critical declined Diseases Effect effective Effectiveness Evidence Frequency Gender help household size implication individual Infection Infectious disease information Interaction involved joint Medical Research Council Meta-analysis MOST None Older Outbreaks participant pathogen pathogen transmission Pathogens physical physical contact populations predict proportion reducing regions researcher respiratory pathogen risk factor SARS-CoV-2 shielding social contact social contact patterns social interaction Spread systematic review Transmission understanding [DOI] 10.7554/eLife.70294 PMC 바로가기 [Article Type] Research Article
Data mining methodology for response to hypertension symptomology—application to COVID-19-related pharmacovigilance고혈압 증상에 대한 데이터 마이닝 방법론 - COVID-19 관련 약물 감시에 적용Research Article Published on 2021-11-232022-09-10 Journal: eLife [Category] MERS, SARS, 치료기술, [키워드] acting acute respiratory illness ADE ADEs Adverse Affect affecting angiotensin Antihypertensive drug antihypertensive drugs Antithrombotic artificial intelligence association beraprost blockers blood pressure bosentan build calcium calcium channel calcium channel blockers candesartan Cluster Combination confounding factor confounding factors coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19-related pharmacovigilance data-driven methodology demographics disease Disease prevalence distribution doxazosin drug drugs effective endothelin receptor antagonist Endothelin receptor antagonists Epoprostenol evaluated exhibited Factor FDA FDA ADE database feature filtered Friedman test funding geometric geometric mean group had no hidden high risk highest hypertension Hypothesis incidence limit macitentan medication medications meta-analyses Meta-analysis methodology monotherapy Nifedipine None operator outcome Patient patients pharmacovigilance Potential potential therapy profile Pulmonary function pulmonary symptomology Quantitative randomized clinical trials Renin renin-angiotensin system reported Reporting respiratory Respiratory illness retrieved rilmenidine selected drug selected drugs selexipag shown Side effect significant difference significant differences significantly higher Sildenafil Stage Tadalafil Therapeutics therapy [DOI] 10.7554/eLife.70734 PMC 바로가기 [Article Type] Research Article
Early prediction of in-hospital death of COVID-19 patients: a machine-learning model based on age, blood analyses, and chest x-ray scoreResearch Article Published on 2021-10-182022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] Admission age Algorithm analyses Analysis Biomarker Blood Brescia build C-reactive protein calculator can be used Chest chest X-ray COVID-19 COVID-19 outbreak COVID-19 patient D-dimer enrolled ferritin Final First wave first-wave function hospital In-hospital death in-hospital mortality Italy lactate dehydrogenase lymphocyte machine-learning monocyte None Patient PDP predict predictor processed random random forests receiver operating characteristic risk ROC ROC Curve second wave SMOTE Support System three group two group variable VIM was used were used [DOI] 10.7554/eLife.70640 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 shedding dynamics across the respiratory tract, sex, and disease severity for adult and pediatric COVID-19Research Advance Published on 2021-08-202022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] Accuracy Action acute respiratory syndrome Adults age Analysis analyzed Canada chair Characteristics characterized children with COVID-19 collected conducted coronavirus coronavirus disease Council COVID-19 COVID-19 severity dataset Deterioration disease severity Engineering facilitate Factors group indicated Industrial infections infectious disease epidemiology Lower respiratory tract LRT natural None Older Pathogenesis pathogenesis of severe COVID-19 Patient pediatric Pediatric infections post-symptom onset predict Predictive prognostic indicator respiratory shedding respiratory tract SARS-CoV-2 SARS-CoV-2 replication Science severe COVID-19 severity Sex stratified systematic review the timing Toronto URT viral clearance Viral load [DOI] 10.7554/eLife.70458 PMC 바로가기 [Article Type] Research Advance
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2Research Article Published on 2021-08-202022-10-31 Journal: eLife [Category] COVID-19, SARS, [키워드] ACE2 Alpha association B.1.1.7 B.1.351 binding Cell change complexes computational method dissociation rate exhibited explain faster humans indicated Interaction introduced MD simulations mechanism Microscopy Molecular dynamics simulation Mutation mutations N501Y N501Y mutation None P.1 Probability protein–protein interaction quantified RBD receptor ACE2 SARS-CoV-2 SARS-CoV-2 spike protein several variant single-molecule force spectroscopy Spike protein Surveillance the RBD the receptor-binding domain transmission of SARS-CoV-2 variants virus [DOI] 10.7554/eLife.69091 PMC 바로가기 [Article Type] Research Article
Physiology and ecology combine to determine host and vector importance for Ross River virusArticle Published on 2021-08-202023-05-31 Journal: eLife [Category] Fulltext, 조류인플루엔자, [키워드] disease spillover emerging arbovirus host competence Next generation matrix None Vector competence [DOI] 10.7554/eLife.67018 PMC 바로가기
Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data아이티에서 개입 목표를 위한 임상 말라리아의 풍토병성과 계절성을 일상 사례 데이터를 사용하여 매핑하기Article Published on 2021-06-012024-08-08 Journal: eLife [Category] 말라리아, [키워드] clinical malaria geospatial statistics None routine surveillance [DOI] 10.7554/eLife.62122 PMC 바로가기