Angiotensin II treatment is associated with improved oxygenation in ARDS patients with refractory vasodilatory shockResearch Published on 2023-12-162024-09-05 Journal: Annals of Intensive Care [Category] update2024, [키워드] Angiotensin II ARDS Norepinephrine renin–angiotensin system septic Shock [DOI] 10.1186/s13613-023-01227-5 PMC 바로가기 [Article Type] Research
Extracorporeal Membrane Oxygenation for COVID-19-Associated Multisystem Inflammatory Syndrome in a 5-year-old5 살짜리 Covid-19 관련 다중 시스템 염증 증후군에 대한 외형 막 산소화Case Reports Published on 2022-02-012022-09-01 Journal: The American Surgeon [Category] MERS, 진단, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Admission Algorithm Anakinra Cardiogenic shock Cardiopulmonary chain Chain Reaction children convalescent plasma Coronary artery coronavirus coronavirus 2 Course COVID-19 COVID-19 convalescent plasma criteria Critical care decannulated demonstrated descending diagnosed discharged home dysfunction ECHO Echocardiogram ECMO epinephrine Extracorporeal extracorporeal membrane oxygenation extracorporeal support feasible High-dose Hydrocortisone Immunoglobulin Inflammatory Intravenous immunoglobulin intravenous methylprednisolone intubation Methylprednisolone Mild Mild symptom mild symptoms MIS-C multisystem inflammatory syndrome in children Norepinephrine Patient PCR Pediatric patient Pediatric patients pediatrics polymerase chain reaction positive reaction remained Remdesivir respiratory respiratory distress SARS-CoV-2 SARS-CoV-2 IgG severe acute respiratory distress syndrome Shock Support syndrome treated Treatment use of ECMO ventricular Viral [DOI] 10.1177/0003134820983198 PMC 바로가기 [Article Type] Case Reports
Longitudinal Cytokine Profile in Patients With Mild to Critical COVID-19경증에서 중요한 코비드 -19 환자의 종 방향 사이토 카인 프로파일Observational Study Published on 2021-12-062022-08-31 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 임상, [키워드] Administered adult COVID-19 patient adult COVID-19 patients ARDS association best Biomarker blood sample Blood samples chemokine clinical endpoint Clinical endpoints coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 Critically ill critically ill patients cytokine cytokine profile Cytokine release syndrome Cytokines disease severity dose early phase elevated evaluate followed by gamma interferon growth highest Hong Kong Hospitalized host response IL-10 IL-1ra IL-5 IL-6 IL-8 immune Inflammation intensive care interferon interferon-induced protein interleukin IP-10 late phase longitudinal Macrophage MCP-1 mDC mechanical ventilation MIG Mild MIP-1α moderate monocyte monocyte chemoattractant protein-1 monokine Norepinephrine observational study Patient patient group patient groups patients predict predicted profile proinflammatory prospective observational study public hospitals receptor receptor antagonist SARS-CoV-2 Seven severity symptom onset was performed with COVID-19 [DOI] 10.3389/fimmu.2021.763292 PMC 바로가기 [Article Type] Observational Study
Impact of ketamine as an adjunct sedative in acute respiratory distress syndrome due to COVID-19 PneumoniaObservational Study Published on 2021-11-012022-10-05 Journal: Respiratory medicine [Category] 임상, [키워드] acute respiratory distress ARDS Care cohort of patient COVID-19 Critical care Deep sedation detrimental Effect hospital Impact increase in introduced Ketamine less material Mechanical mechanical ventilation median medication Norepinephrine Patient pharmacological propofol receiving reduced reducing required retrospective Sedation shown significantly lower single center syndrome Vasopressor vasopressor requirement vasopressors with COVID-19 [DOI] 10.1016/j.rmed.2021.106667 PMC 바로가기 [Article Type] Observational Study
Blood purification with CytoSorb in critically ill COVID-19 patients: A case series of 26 patients중환자 COVID-19 환자에서 CytoSorb를 사용한 혈액 정화: 26명의 환자에 대한 사례 시리즈Article Published on 2021-11-012022-09-11 Journal: Artificial organs [Category] MERS, SARS, 바이오마커, [키워드] (procalcitonin accompanied acute respiratory distress acute respiratory distress syndrome ARDS best C-reactive protein case sery Complication Confidence intervals coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critically ill Cytokine storm Cytosorb effective expressed failure feasible ferritin form hemoadsorption hemodynamic hyperinflammation ICU Inflammatory intensive care intensive care unit knowledge Laboratory Lung function marker median moderate moderate ARDS Norepinephrine organ function PaO Patient patients with COVID-19 plasma concentration post treatment procalcitonin purification respiratory distress Respiratory distress syndrome Retrospective study SARS-CoV-2 positive patient SARS-CoV-2 positive patients Sepsis Sequential Organ Failure Assessment significant decrease significantly SOFA score survived syndrome therapy treated Treatment [DOI] 10.1111/aor.14024 PMC 바로가기 [Article Type] Article
Early Effects of Passive Leg-Raising Test, Fluid Challenge, and Norepinephrine on Cerebral Autoregulation and Oxygenation in COVID-19 Critically Ill PatientsNeurology Published on 2021-06-162022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] administration Affect Autoregulation cerebral cerebral autoregulation Cerebral oxygenation challenge clinical conditions clinically conducted Coronavirus disease 2019 COVID-19 COVID-19 patients diastolic Doppler Effect evaluate the effect Factor fluid challenge hemodynamic high risk Ill indicated interquartile range Italy maintain male mean arterial pressure mechanically ventilated median age Neurological complication Neurological complications Non-invasive Norepinephrine outcome Oxygenation Passive passive leg raising test Patient patients paucity of data Primary outcome Prospective Study raising secondary severe COVID-19 patients significant increase Test therapeutic intervention treated variables Ventilated was increased [DOI] 10.3389/fneur.2021.674466 PMC 바로가기 [Article Type] Neurology
Collective Critical Care Ambulance: an innovative transportation of critical care patients by bus in COVID-19 pandemic responseOriginal Research Published on 2021-06-042022-10-29 Journal: Scandinavian Journal of Trauma, Resuscitation and [Category] Coronavirus, MERS, SARS, [키워드] adverse effect affected ALS Ambulance benefit collective Collective transport condition COVID-19 pandemic COVID-19 patient critical care patient Critical care transport Critically ill patient disaster disorder Efficiency emergency medical service Epidemic equipment evaluate event expected feasibility France hemodynamic instability ICU intensive care patient intensive care unit Interhospital transfer of critically ill patients Intubated less life mass Mass casualty incidents Norepinephrine occurred Patient performed reduce resource Result Support the mean transfer transferred transported vector Ventilation [DOI] 10.1186/s13049-021-00896-0 PMC 바로가기 [Article Type] Original Research
Guanfacine’s mechanism of action in treating prefrontal cortical disorders: Successful translation across speciesResearch article Published on 2020-12-012022-10-05 Journal: Neurobiology of Learning and Memory [Category] 비임상, [키워드] Abstract addition ADHD Alter anti-inflammatory action Attention benefit Brain cognitive cortical deficit dendritic Effect Evidence executive expand explain function functions Guanfacine inhibit Injury Intuniv mechanism of action memory Mental disorder Mental Disorders microglia modulation neuronal NMDAR Norepinephrine off-label plasticity Potassium reducing Research Schizophrenia selective Signaling Stress stress-related disorder synaptic therapeutic action translation translational variety Working memory α2A-adrenoceptor [DOI] 10.1016/j.nlm.2020.107327 [Article Type] Research article
CytoResc – “CytoSorb” Rescue for critically ill patients undergoing the COVID-19 Cytokine Storm: A structured summary of a study protocol for a randomized controlled trialCytoResc – COVID-19 사이토카인 폭풍을 겪고 있는 중환자를 위한 "CytoSorb" 구조: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-06-262022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 24 hour 24 hours Acute kidney injury Acute respiratory failure Administered Analysis Antibiotics arterial arterial pressure Bacterial Berlin blinded Blinding block blocks Blood C-reactive protein C-reactive protein (CRP catecholamine cause center Chain Reaction Charité clinical Clinical course Clinical practice clinical trials clinically clinician comparator concentrations condition conducted contraindication COVID-19 COVID-19 patient COVID-19 patients Critical care Critically ill critically ill COVID-19 patients Critically ill patient critically ill patients cytokine Cytokine storm Cytokines Cytosorb CytoSorb® data set death defined dissemination dose element elevated Endpoint extracorporeal cytokine elimination feasibility Filter Formal Germany Hemodynamics hospital discharge Hospitalization hospitalized patient hospitalized patients hyperinflammation Hyperinflammatory ICU-treatment ICUs IIb IL-6 IMPROVE Inc. Inclusion inclusion criteria indication intensive care unit intensive care units interleukin interleukin-6 intervention effect mean arterial pressure mechanical ventilation molecular weight Mortality multicenter New Norepinephrine number objective observational study occur Open-label other conditions outcome parallel group participant Patient patients PCR PCT performed phase pilot study polymerase chain polymerase chain reaction polystyrene positive pressure Prevent primary endpoint procalcitonin Proinflammatory cytokine proinflammatory cytokines protocol randomization Randomized Randomized controlled trial reason for receive recruited reducing Registered registry renal replacement therapy replacement therapy rescue Respiratory failure Safety Safety assessment Sample size SARS-CoV-2 secondary Secondary outcomes Shock shown Standard of care statistician status stratified Study design Study protocol Suspected therapy toxin Treatment Trial Trial registration USA vasoplegic shock Vasopressor vasopressors website [DOI] 10.1186/s13063-020-04501-0 PMC 바로가기 [Article Type] Letter
The link between chronic pain and Alzheimer’s diseaseReview Published on 2019-11-062024-09-02 Journal: Journal of Neuroinflammation [Category] 대상포진, [키워드] Alzheimer’s disease chronic pain locus coeruleus microglia Noradrenergic system Norepinephrine Prefrontal cortex [DOI] 10.1186/s12974-019-1608-z PMC 바로가기 [Article Type] Review