Nup98

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition antagonistic antagonize interferon signaling Antiviral antiviral action antiviral response antiviral signaling arginine bind binding C-terminal domain causative agent complex coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical Defense disrupt docking Health health problem Host Host immune response host immune responses IFN IFN signaling IFN-stimulated gene IFN-stimulated genes immune responses impair Infection inhibit interact interferon interferon signaling antagonism ISGs mechanism methionine NPC nuclear nuclear pore nuclear translocation Nup98 ORF6 overcome pandemic pathogenic virus pathogenic viruses Pathogens pathway Previous studies previous study Protein Rae1 replicate residue respiratory SARS-CoV SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Significance STAT Stat1 STAT2 STATs the interferon transcriptional Vaccines Viral viral pathogen viral pathogens virus virus viruses
[DOI] 10.1073/pnas.2016650117 PMC 바로가기 [Article Type] 530