Identification of CKD, bedridden history and cancer as higher-risk comorbidities and their impact on prognosis of hospitalized Omicron patients: a multi-centre cohort studyArticle Published on 2022-12-012022-11-16 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 치료기술, [키워드] advanced age age Cancer China Chronic kidney disease CKD cohort study Comorbidity condition conditions COVID-19 critical cases enrolled Factor female first positive hospialized population Hospitalized hospitalized patient hypertension identification Logistic regression Metabolic disorders multivariate Observational cohort study omicron participant Patient patients Primary outcome Prognosis progression risk factor Risk factors SARS-CoV-2 SARS-CoV-2 detection secondary outcome severity Shanghai suggested vaccination viral shedding [DOI] 10.1080/22221751.2022.2122581 PMC 바로가기
Demographic, behavioural and occupational risk factors associated with SARS-CoV-2 infection in UK healthcare workers: a retrospective observational studyArticle Published on 2022-11-072022-11-15 Journal: BMJ Open [Category] SARS, 변종, 진단, [키워드] 95% CI Analysis assessment behavioural COVID-19 demographic Diseases effective enhanced enrolled Epidemiology Factor General population HCW HCWs Health healthcare Healthcare system healthcare worker higher risk highest hospital identify include Infection infection control investigated Logistic regression measure multivariate logistic regression Observational cohort study occupational Pandemics Personal protective equipment Physiotherapist positive PPE Public public health questionnaire Regression model Reporting Resilience retrospective risk risk factor risk reduction SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 variant Selection Shrinkage social distancing social distancing measures stability sustained Vaccine variable was used Workplace [DOI] 10.1136/bmjopen-2022-063159 PMC 바로가기
Association between treatment failure and hospitalization after receipt of neutralizing monoclonal antibody treatment for COVID-19 outpatientsArticle Published on 2022-11-072022-11-16 Journal: BMC Infectious Diseases [Category] SARS, 변종, [키워드] 95% CI 95% confidence interval adjusted odds ratio Administered age Characteristics clinical trial Comorbidity COVID-19 COVID-19 outpatient death defined died early symptomatic COVID-19 effective Electronic health record health system Hospitalization Hospitalized immunocompromised status lack mAb mAbs Male sex Mild monoclonal antibodies monoclonal antibody monoclonal antibody treatment Mortality mortality data multicenter Neutralizing obesity Observational cohort study occurred pandemic Patient patients patients with COVID-19 positive Primary outcome real-world data reducing SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 vaccination Treatment Vaccine variants while [DOI] 10.1186/s12879-022-07819-z PMC 바로가기
Pulmonary Involvement in SARS-CoV-2 Infection Estimates Myocardial Injury RiskArticle Published on 2022-10-112022-11-15 Journal: Medicina [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute respiratory syndrome Admission age Alpha alveolar ambient biochemical biochemical marker Biomarker C reactive protein can be used cardiac injury chest scan Computerized tomography consecutive patients consolidation coronavirus correlated correlation COVID-19 COVID-19 complications COVID-19 patient COVID-19 risk factors CRP CT scan Diastolic blood pressure dysfunction elevated estimate Factor Factors fibrinogen group Hospitalization IL-6 Infection Inflammatory marker Injury interleukin-6 interlobular septal thickening interstitial Involvement lactate dehydrogenase LDH lesion lung Lung disease lung involvement material multisystemic myocardial injury myocardial involvement Myoglobin Necrosis non-specific NT-proBNP objective Observational cohort study occurred parameters pathology Patient Patient care performed peripheral oxygen saturation Pneumonia pulmonary pulmonary involvement pulmonary lobe radiological Registered respiratory rate respiratory rates Result risk routine SARS-CoV-2 SARS-COV-2 infection Serum ferritin severity Sex significant difference Systolic blood pressure the disease the patient the study group TnI [DOI] 10.3390/medicina58101436 PMC 바로가기
Molnupiravir When Used Alone Seems to Be Safe and Effective as Outpatient COVID-19 Therapy for Hemodialyzed Patients and Kidney Transplant RecipientsArticle Published on 2022-10-092022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 치료제, [키워드] Acute kidney injury antiviral activity automated Comorbidity concerning cough COVID-19 COVID-19 therapy demonstrated diagnosed with COVID-19 dose Efficacy ESKD ESRD Fever Hemodialysis Immunosuppressive medication in vitro Interaction joint kidney Kidney disease kidney transplant kidney transplant recipient kidney transplant recipients Kidney transplantation knowledge molnupiravir Nasopharyngeal swab specimens nucleic acid amplification Observational cohort study Outpatient Pain Patient performed Poland positive-sense recipient resolved retrospective RNA viruses SARS-CoV-2 SARS-COV-2 infection serum creatinine Side effect therapy Transplant Treatment weakness [DOI] 10.3390/v14102224 PMC 바로가기
Impact of variant of concern and vaccination status on COVID-19 infection virological dynamics in end stage kidney disease patients receiving haemodialysisArticle Published on 2022-10-012022-11-16 Journal: Nephrology (Carlton, Vic.) [Category] COVID19(2023년), SARS, 변종, [키워드] Affect Cohort COVID-19 COVID-19 illness COVID-19 infection De-isolation dialysis Haemodialysis Impact inactive individual Infection Kidney disease Negative PCR Observational cohort study Patient PCR cycle PCR-confirmed COVID-19 performed polymerase chain prolonged viral shedding protocol receiving required retrospective subject Swab threshold value time vaccination variant variant of concern variants Viral load Virological virus Virus shedding [DOI] 10.1111/nep.14084 PMC 바로가기
Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccinationArticle Published on 2022-10-012022-11-16 Journal: RMD Open [Category] COVID19(2023년), SARS, 변종, [키워드] administration Arthritis booster booster vaccination control group COVID-19 COVID-19 vaccination demonstrated Epidemiology impairment medication methotrexate mRNA MTX neutralisation neutralising Observational cohort study occur omicron Patient Prevent pseudovirus neutralisation assay reached receiving SARS-CoV-2 serum significantly higher significantly lower therapy Treatment vaccination vaccine response variant variants were assessed while wild-type [DOI] 10.1136/rmdopen-2022-002639 PMC 바로가기
Risk factors associated with hospitalization in patients with asymptomatic or mild COVID-19 in public accommodation facilities in TokyoObservational Study Published on 2022-10-012022-10-04 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age association Care conducted coronavirus disease COVID-19 COVID-19 patient Cox regression Cox regression analysis Cox regression model diabetes epidemiological data evaluated Factor Fever Gout groups hazard ratio high risk Hospitalization Hospitalized hospitalized patient Japan medical intervention medication Mild obesity Observational cohort study Oxygen administration Patient patients with asymptomatic patients with COVID-19 provided psychiatric disease Psychiatric medication Recovery accommodation facility. required risk factor sensitivity analysis severe respiratory symptoms significantly higher Symptom the median Tokyo underlying disease [DOI] 10.1016/j.jiac.2022.06.002 PMC 바로가기 [Article Type] Observational Study
Immunogenicity of two COVID-19 vaccines used in India: An observational cohort study in health care workers from a tertiary care hospitalArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] adenoviral-vectored vaccine antibodies blood sample booster Care Cell collected Covaxin COVID-19 COVID-19 case COVID-19 vaccine Covishield diminished dose elicited ELISA full-length Health care worker hospital immune response Immunity immunization immunogenicity independent India initiated IQR long-term follow up median Neutralizing Neutralizing antibody titer Observational cohort study pandemic PBMC pre-vaccination progression recipient recipients remained SARS CoV-2 Seroconversion T cell T cell response T-cell Response tested Vaccine Vaccines were recorded were used [DOI] 10.3389/fimmu.2022.928501 PMC 바로가기
Safety, immunogenicity, and immune persistence of two inactivated COVID-19 vaccines replacement vaccination in China: An observational cohort studyArticle Published on 2022-09-162022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] administration Adverse reaction All participant anti-SARS-CoV-2 approved BBIBP-CorV can be used China Complete control group COVID-19 COVID-19 vaccine Cytopathic effect dose doses first dose geometric mean concentration geometric mean titer GMCs GMTs healthy immune persistence immunogenicity Immunoglobulin inactivated Inactivated vaccine Mild mitigate moderate NAb National not different not significantly different observation Observational cohort study Pragmatic regimens replacement Replacement vaccine Safety safety profile SARS-CoV-2 strain second dose sera severity Standard subject vaccination WHO [DOI] 10.1016/j.vaccine.2022.08.037 PMC 바로가기