In reference to Intranasal Corticosteroid Treatment on Recovery of Long-Term Olfactory Dysfunction Due to COVID-19Article Published on 2023-04-012023-07-11 Journal: The Laryngoscope [Category] COVID19(2023년), [키워드] Anosmia coronavirus Corticosteroids COVID-19 maxillofacial surgery olfactory dysfunction olfactory function SARS-CoV-2 Smell [DOI] 10.1002/lary.30505 PMC 바로가기
Prevalence of acute olfactory dysfunction differs between variants of SARS-CoV-2-results from chemosensitive testing in wild type, VOC alpha (B.1.1.7) and VOC delta (B.1617.2)Article Published on 2022-11-012022-11-16 Journal: European archives of oto-rhino-laryngology : offic [Category] COVID19(2023년), SARS, 변종, [키워드] acute SARS-CoV-2 infection Alpha B.1.1.7 blinded COVID-19 dysfunction Hyposmia impairment Next-generation sequencing Olfaction olfactory olfactory dysfunction olfactory function Patient Prevalence Prospective Study quantitative real-time PCR SARS-CoV-2 significant difference Smell subsequent symptoms of COVID-19 variant variants virus virus variant VoC wild type [DOI] 10.1007/s00405-022-07431-6 PMC 바로가기
Why Does the Omicron Variant Largely Spare Olfactory Function? Implications for the Pathogenesis of Anosmia in Coronavirus Disease 2019Article Published on 2022-10-172022-11-16 Journal: The Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 acute respiratory syndrome alkaline Anosmia cause Cell coronavirus COVID-19 D614G D614G mutation Efficiency Express expressing host cell hydrophobic less Loss of Smell Mucus Mutation olfactory dysfunction Olfactory epithelium olfactory function omicron Omicron variant penetration potential mechanism Prevalence Receptor binding reduce reduced SARS-CoV-2 Support target cell tissue tropism TMPRSS2 transmembrane serine protease variants [DOI] 10.1093/infdis/jiac113 PMC 바로가기
COCOS trial: CO rticosteroids for CO VID-19-induced loss of S mell-protocol for a single-centred, double-blind, randomised, placebo-controlled trialCOCOS 시험: 단일 중심, 이중 맹검, 무작위, 위약 대조 시험을 위한 CO VID-19 유발 S mell-protocol 손실에 대한 CO rticosteroidsArticle Published on 2022-08-102022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] addition Anosmia approved center Corticosteroids COVID-19 COVID-19 diagnosis determine disorder disorders double-blind early phase Efficacy Ethics gustatory function High-dose Hyposmia hypothesised IMPROVE include Inclusion induce Infectious diseases Inflammation institutional review board local inflammatory response Loss of Smell matching placebo Most patient Most patients nasal olfactory olfactory function olfactory nerve otolaryngology outcome pathway Patient peer-reviewed persist Placebo placebo-controlled trial positive Prednisolone Primary outcome Quality of life Questionnaires randomised receive reduce registration number Research protocol secondary Secondary outcomes stick Symptoms Treatment Trial university [DOI] 10.1136/bmjopen-2021-060416 PMC 바로가기 [Article Type] Article
Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology?정신 장애의 후각 장애: 비염이 질병 정신 생리학에 영향을 줍니까?Review Published on 2022-08-052022-09-11 Journal: Translational Psychiatry [Category] 유전자 메커니즘, [키워드] adverse effect Brain brain development cause Clinical studies clinical study contribute coronavirus disease Coronavirus disease 2019 COVID-19 Critical Depression disease environmental factor environmental factors Evidence followed by functions illness impairment Inflammation involved long-lasting Mental nasal Neuropsychiatric olfactory olfactory dysfunction olfactory function outbreak outcome pathophysiological mechanism pathophysiological mechanisms pathophysiology produced Psychiatric Psychiatric disorders Psychopathology recent Regulation Research respiratory viral infection respiratory viral infections risk Schizophrenia [DOI] 10.1038/s41398-022-02081-y PMC 바로가기 [Article Type] Review
Aromatherapy blend of thyme, orange, clove bud, and frankincense boosts energy levels in post-COVID-19 female patients: A randomized, double-blinded, placebo controlled clinical trialRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: Complementary therapies in medicine [Category] SARS, 임상, [키워드] acute COVID-19 acute infection Analysis aromatherapy assigned baseline BMI boost conducted Controlled clinical trial COVID-19 Diagnosis double blind double-blinded effect size employment Essential evaluate Evidence fatigue female FIVE group healthy IMPROVE individual Infection Inhaled Insomnia Intervention inventory lack Mental Oil olfactory function outcome Placebo placebo controlled trial proportion provide Quality of life Randomized recovering from COVID-19 secondary serious complication significantly significantly lower survivor Symptom the United State USA Utah were measured women [DOI] 10.1016/j.ctim.2022.102823 PMC 바로가기 [Article Type] Randomized Controlled Trial
In Response to Clinical Features of Parosmia Associated with COVID-19 InfectionComment Published on 2022-07-012023-07-08 Journal: The Laryngoscope [Category] COVID19(2023년), [키워드] Anosmia coronavirus COVID-19 olfactory dysfunction olfactory function parosmia SARS-CoV-2 Smell [DOI] 10.1002/lary.30134 PMC 바로가기 [Article Type] Comment
Cognitive dysfunction associated with COVID-19: A comprehensive neuropsychological studyShort communication Published on 2022-06-012022-10-05 Journal: Journal of psychiatric research [Category] 바이오마커, [키워드] acute infection age alteration Anxiety Characteristics cognitive Cognitive function cognitive performance correlated correlation COVID COVID-19 COVID-19 patient cross-sectional study Depression determine domains dysfunction evaluate evaluated Evidence executive fatigue Future healthy control intrinsic long-term COVID mechanism memory Neuropsychological assessment Normative objective olfactory dysfunction olfactory function olfactory test pathophysiology Patient patients with COVID-19 protocol recent reduced Result selective sleep quality Symptom syndrome were used with COVID-19 [DOI] 10.1016/j.jpsychires.2022.03.033 [Article Type] Short communication
Intranasal delivery of SARS-CoV-2 spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafishSARS-CoV-2 스파이크 단백질의 비강 내 전달은 제브라피쉬에서 후각 손상, 염증 및 후각 기능 장애를 유발하기에 충분합니다Article Published on 2022-05-012022-09-11 Journal: Brain, behavior, and immunity [Category] COVID19(2023년), SARS, 치료기술, [키워드] animal animal models animals Anosmia bind cause Cell characterized cilia Cluster Combined damage Danio direct infection driven by edema endothelial EOG explained expression fish food functional hemorrhage hemorrhages Histopathology implication indicated Infection Inflammation Inflammatory response Inflammatory responses intranasal intranasally Loss of Smell mechanism myeloid cell nasal epithelium non-neuronal cell non-neuronal cells olfactory Olfactory damage olfactory dysfunction olfactory function Olfactory organ olfactory receptor Olfactory receptor expression organ prevalent Protein RBD receptor reduced response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S SARS-CoV-2 spike SARS-CoV-2 spike protein sensory neuron spike Spike protein Symptom treated Vaccine Viral protein Viral proteins widespread zebrafish Zebrafish (Danio rerio). [DOI] 10.1016/j.bbi.2022.03.006 PMC 바로가기 [Article Type] Article
High prevalence of long-term olfactory dysfunction confirmed by olfactory testing after a community COVID-19 outbreakOriginalien Published on 2021-12-232022-11-01 Journal: Hno [Category] COVID-19, MERS, SARS, [키워드] Anosmia Ausbruch averaged chemosensory Community convalescent coronavirus coronavirus disease correlated COVID-19 COVID-19 outbreak determine dysfunction examined female Germany Geruch Gustatory gustatory function Hypogeusia Hyposmia Langzeitfolgen Long-term sequelae median nasal Olfaction olfactory olfactory dysfunction olfactory function outbreak participant population-based cohort Prevalence proportion reliability Result resulting SARS-CoV‑2 infection Schmecken Smell the study group threshold [DOI] 10.1007/s00106-021-01129-7 PMC 바로가기 [Article Type] Originalien