In Vivo Immune-Modulatory Activity of Lefamulin in an Influenza Virus A (H1N1) Infection Model in MiceArticle Published on 2024-05-152024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] acute lung injury (ALI) acute respiratory distress syndrome (ARDS) Anti-inflammatory Antiviral Azithromycin community-acquired pneumonia Cytokines lefamulin Lung histopathology oseltamivir [DOI] 10.3390/ijms25105401 PMC 바로가기 [Article Type] Article
Pneumococcal sialidase promotes bacterial survival by fine-tuning of pneumolysin-mediated membrane disruption폐렴구균 시알리다아제가 폐렴리신 매개 막 파괴의 미세 조정을 통해 세균 생존을 촉진한다.Article Published on 2024-03-262024-08-24 Journal: Cell Reports [Category] 폐렴구균 감염증, [키워드] CP: Cell biology CP: Microbiology cytotoxicity endosome disrupture NanA NanoBiT nanobody oseltamivir Pneumolysin sialic acid Streptococcus pneumoinae Xenophagy
Pre-Clinical Evaluation of the Antiviral Activity of Epigalocatechin-3-Gallate, a Component of Green Tea, against Influenza A(H1N1)pdm VirusesArticle Published on 2023-12-162024-09-05 Journal: Viruses [Category] update2024, [키워드] Combinational therapy Epigalocatechin-3-gallate ferret model influenza antiviral treatment influenza viruses oseltamivir polyphenol [DOI] 10.3390/v15122447 PMC 바로가기 [Article Type] Article
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like propertiesArticle Published on 2023-04-052023-06-24 Journal: European journal of medicinal chemistry [Category] 신종인플루엔자, [키워드] 150-cavity drug resistance Influenza virus neuraminidase inhibitors oseltamivir [DOI] 10.1016/j.ejmech.2023.115275
Development of a Corticosteroid-Immunosuppressed Mouse Model to Study the Pathogenesis and Therapy of Influenza-Associated Pulmonary AspergillosisBrief Report Published on 2023-04-012024-09-05 Journal: Nanoscale [Category] update2024, [키워드] amphotericin B aspergillosis Corticosteroids Influenza mouse model oseltamivir Pneumonia [DOI] 10.1093/infdis/jiad001 PMC 바로가기 [Article Type] Brief Report
An oseltamivir-resistant avian H1N1 influenza A virus can transmit from mallards to chickens similarly to a wild-type strain: implications for the risk of resistance transmission to humans오셀타미비르 내성 조류 H1N1 인플루엔자 A 바이러스는 야생형 균주와 유사하게 청둥오리에서 닭으로 전파될 수 있으며, 이는 인간에게 내성 전파의 위험에 대한 함의를 가진다.Article Published on 2023-04-012023-05-31 Journal: The Journal of General Virology [Category] 신종인플루엔자, 조류인플루엔자, [키워드] antiviral resistance Avian Influenza chicken neuraminidase inhibitor oseltamivir pandemic preparedness [DOI] 10.1099/jgv.0.001835
Counterintuitive effect of antiviral therapy on influenza A-SARS-CoV-2 coinfection due to viral interferenceArticle Published on 2023-02-082024-09-05 Journal: bioRxiv [Category] update2024, [키워드] Coinfection COVID-19 Influenza virus interferon response interferon stimulated genes oseltamivir respiratory virus SARS-CoV-2 Tamiflu viral interference [DOI] 10.1101/2023.02.07.527372 PMC 바로가기 [Article Type] Article
Population analysis of oseltamivir-resistant variants for the rapid prediction of drug susceptibility by real-time reverse transcription polymerase chain reactionArticle Published on 2022-12-212023-06-23 Journal: Fukushima journal of medical science [Category] 신종인플루엔자, [키워드] Influenza neuraminidase inhibitor oseltamivir polymerase chain reaction resistant virus. [DOI] 10.5387/fms.2022-15 PMC 바로가기
Low prevalence of influenza A strains with resistance markers in Brazil during 2017-2019 seasonsArticle Published on 2022-09-142023-06-23 Journal: Frontiers in Public Health [Category] 신종인플루엔자, [키워드] adamantane baloxavir marboxil influenza A virus Neuraminidase (NA) inhibitors oseltamivir resistance [DOI] 10.3389/fpubh.2022.944277 PMC 바로가기
Predicting Permissive Mutations That Improve the Fitness of A(H1N1)pdm09 Viruses Bearing the H275Y Neuraminidase SubstitutionArticle Published on 2022-08-102023-06-14 Journal: Journal of Virology [Category] Fulltext, 신종인플루엔자, [키워드] antivirals Influenza oseltamivir resistance [DOI] 10.1128/jvi.00918-22 PMC 바로가기