Combination therapy with remdesivir and immunomodulators improves respiratory status in COVID-19: A retrospective studyArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% confidence interval Analysis Baricitinib baseline benefit body mass index combination therapy Concomitant contributed control group coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Day Diabetes Mellitus examined faster greater hazard ratio immunomodulator immunomodulators IMPROVE in both group independent investigated median outcome Oxygen administration Patient patients Prognostic factors Remdesivir respiratory recovery retrospective Retrospective study severity single-center study standard treatment supplemental oxygen survival synergistic therapy Tocilizumab treated two group [DOI] 10.1002/jmv.28037 PMC 바로가기
Risk factors associated with hospitalization in patients with asymptomatic or mild COVID-19 in public accommodation facilities in TokyoObservational Study Published on 2022-10-012022-10-04 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age association Care conducted coronavirus disease COVID-19 COVID-19 patient Cox regression Cox regression analysis Cox regression model diabetes epidemiological data evaluated Factor Fever Gout groups hazard ratio high risk Hospitalization Hospitalized hospitalized patient Japan medical intervention medication Mild obesity Observational cohort study Oxygen administration Patient patients with asymptomatic patients with COVID-19 provided psychiatric disease Psychiatric medication Recovery accommodation facility. required risk factor sensitivity analysis severe respiratory symptoms significantly higher Symptom the median Tokyo underlying disease [DOI] 10.1016/j.jiac.2022.06.002 PMC 바로가기 [Article Type] Observational Study
Effects of mild obesity on outcomes in Japanese patients with COVID-19: a nationwide consortium to investigate COVID-19 host genetics Research Published on 2022-08-092022-10-05 Journal: Nutrition & Diabetes [Category] SARS, 바이오마커, 유전자 메커니즘, 치료법, [키워드] adjusted adjusted odds ratio Analysis analyzed benefit BMI body mass index class coronavirus disease COVID-19 COVID-19 patient Critical Critical case critical cases defined died disease severity Effect enrolled force host genetics independent risk factor indicated intensive care Invasive mechanical ventilation Japan Japanese Mild mortality rate multiple logistic regression no difference obesity Odds ratio outcome Oxygen administration Oxygenation Patient patients with COVID-19 reported required Respiratory failure Result risk risk factor severe COVID-19 severe disease severity of COVID-19 stratified the patient treated [DOI] 10.1038/s41387-022-00217-z [Article Type] Research
Closed-loop oxygen control improves oxygen therapy in acute hypoxemic respiratory failure patients under high flow nasal oxygen: a randomized cross-over study (the HILOOP study)Randomized Controlled Trial Published on 2022-04-142022-10-04 Journal: Critical Care [Category] 임상, [키워드] 95% confidence interval Acute respiratory failure AHRF assigned Automatic Automatic oxygen titration Closed-loop oxygen control COVID-19 pandemic Critically ill patient cross-over cut-off Efficacy event groups healthcare personnel HFNO High flow nasal cannula High-flow nasal oxygen hypoxemic IMPROVE less moderate nasal Nasal high-flow. nasal oxygen not significantly different oxygen Oxygen administration oxygen supply Oxygen therapy Oxygenation Patient patients with moderate Primary outcome Randomized Randomly Registered Respiratory failure therapy treated [DOI] 10.1186/s13054-022-03970-w PMC 바로가기 [Article Type] Randomized Controlled Trial
Severe Acute Respiratory Syndrome Coronavirus 2 RNAemia and Clinical Outcomes in Children With Coronavirus Disease 2019Article Published on 2022-01-182022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 치료기술, [키워드] acute respiratory syndrome Admission children clinical clinical manifestations Cohort coronavirus coronavirus 2 coronavirus disease COVID-19 disease disease severity fraction Hospitalization Hospitalized Infants intensive care interquartile range median outcomes Oxygen administration plasma respiratory risk RNA RNAemia SARS-CoV-2 severe disease subset Viremia with COVID-19 [DOI] 10.1093/infdis/jiab491 PMC 바로가기
Clinical characteristics of pregnant women with COVID-19 in Japan: a nationwide questionnaire surveyResearch Published on 2021-09-182022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, [키워드] acute respiratory syndrome Asymptomatic caesarean sections Characteristics clinical Clinical characteristics collected conducted coronavirus coronavirus disease country COVID-19 COVID-19 infection COVID‐19 death delivery diagnosed with COVID-19 died epidemiological examined FIVE gestation period incidence Infection Infection prevention Infection route Japan National outcome outcome measure Oxygen administration Pneumonia positive rate Pregnancy pregnant women questionnaire reported respiratory symptoms response Result risk factor route of infection SARS-CoV-2 SARS-CoV-2 transmission screening test severe cases Severe infection Symptom symptomatic Symptoms Transmission Treatment were assessed with COVID-19 women [DOI] 10.1186/s12884-021-04113-9 PMC 바로가기 [Article Type] Research
Investigation of the optimal method of oxygen administration with simultaneous use of a surgical mask: a randomized control studyRandomized Controlled Trial Published on 2021-09-072022-10-04 Journal: Journal of anesthesia [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] administer Administered administration anesthesiologist Compliance Concentration Coronavirus disease 2019 COVID-19 dispersal end-tidal group healthy volunteers help Infection prevention investigated investigation Mask median value nasal Operating room oxygen Oxygen administration Oxygen reserve index Oxygenation pandemic Patient patients Perspective Prevent random randomized control study Result same order statistically significant difference subject supplementary material surgical surgical mask the patient wearing [DOI] 10.1007/s00540-021-02998-6 PMC 바로가기 [Article Type] Randomized Controlled Trial
High-flow Nasal Cannula therapy: A feasible treatment for vulnerable elderly COVID-19 patients in the wardsResearch article Published on 2021-09-012022-10-05 Journal: Heart & lung : the journal of critical care [Category] SARS, 치료법, [키워드] cannula clinical COVID-19 COVID-19 patient COVID-19 patients eligible feasible frailty HFNC HFNC therapy High-flow nasal cannula hospital hospital discharge Hypoxemia hypoxemic intensive care unit Invasive mechanical ventilation mechanical ventilation median age nasal objective Oxygen administration Patient patients persists primary endpoint reported Respiratory failure Result retrospective cohort study score survival rate therapy Tolerability Treatment [DOI] 10.1016/j.hrtlng.2021.04.008 [Article Type] Research article
Epidemiology of Coronavirus Disease Outbreak among Crewmembers on Cruise Ship, Nagasaki City, Japan, April 2020Synopsis Published on 2021-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] acute respiratory syndrome age Atlantica city coronavirus coronavirus disease COVID-19 COVID-19 outbreak Cruise ship death Epidemiology health monitoring Health status Hospitalized Infection Isolation Japan laboratory-confirmed men Nagasaki occurred outbreak Oxygen administration peaked Pneumonia quarantine required respiratory infections resulting SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Spread supported Surveillance virus viruses zoonoses [DOI] 10.3201/eid2709.204596 PMC 바로가기 [Article Type] Synopsis
CBmeter study: protocol for assessing the predictive value of peripheral chemoreceptor overactivation for metabolic diseasesClinical Trial Published on 2021-08-262022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] Algorithms analysed Analysis approved asked carotid clinical study Clustering analysis coded contribute diabete diabetics Diagnosis disease early diagnosis ethics committee Glucose gold standard guidelines Health health informatics healthcare Healthcare systems ingestion interstitial Intervention metabolic disease metabolic disturbances Non-invasive Oxygen administration oxygen saturation participant Patient peer-reviewed peripheral chemoreceptor Physiology Predictive protocol protocols & quantification recent recruited respiratory rate response Result Stratification Therapeutic approach type 2 diabete ventilatory [DOI] 10.1136/bmjopen-2020-042825 PMC 바로가기 [Article Type] Clinical Trial