Reliability and clinical correlations of semi-quantitative lung ultrasound on BLUE points in COVID-19 mechanically ventilated patients: The ‘BLUE-LUSS’-A feasibility clinical studyArticle Published on 2022-10-142022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 치료기술, [키워드] clinical study correlated correlation COVID-19 COVID-19 pandemic Critically ill Critically ill patient critically ill patients diagnostic feasibility ICUs independent indicated information intensive care intensive care unit Intervention lung Lung pathology mechanically ventilated P/F P/F ratio positive reduce Region reliability risk of infection RT-PCR SARS-CoV2 semi-quantitative significantly single-center the patient Treatment university Variability ventilated patient was performed were recorded [DOI] 10.1371/journal.pone.0276213 PMC 바로가기
Increased respiratory dead space could associate with coagulation activation and poor outcomes in COVID-19 ARDSResearch article Published on 2022-10-012022-10-05 Journal: Journal of critical care [Category] 바이오마커, [키워드] Activation APACHE II ARDS Coagulation correlated COVID-19 COVID-19 patients Critically ill D-dimer D-dimer level determine discharge discharged enrolled help identify Increased Invasive mechanical ventilation less likelihood material measurement mechanical ventilation outcome outcomes P/F ratio Patient patients with COVID-19 performed Pneumonia primary endpoint Respiratory dead space Respiratory system Result static compliance subgroup of patient supported volumetric Volumetric capnography [DOI] 10.1016/j.jcrc.2022.154095 [Article Type] Research article
Soluble urokinase Plasminogen Activator Receptor (suPAR) levels are predictive of COVID-19 severity: an Italian experienceResearch article Published on 2022-09-012022-10-05 Journal: Clinical immunology (Orlando, Fla.) [Category] 바이오마커, 진단, [키워드] activator BPAP calprotectin cannula Chorus circulating Concentration correlation COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity CPAP disease severity evaluate expressed helping IL-1β IL-6 Inflammatory inflammatory markers IQR Italian Italy lymphocyte counts marker Mask mortality rate neutrophil neutrophil count NLR P/F ratio plasminogen positive correlation Predictive prognostic biomarker Ratio representing respiratory Respiratory Support Result risk Risk assessment shown suPAR survival rate tested the disease therapy TNF-α were used [DOI] 10.1016/j.clim.2022.109091 [Article Type] Research article
Capnodynamic monitoring of lung volume and blood flow in response to increased positive end-expiratory pressure in moderate to severe COVID-19 pneumonia: an observational studyObservational Study Published on 2022-07-312022-10-05 Journal: Critical Care [Category] 임상, [키워드] ANOVA arterial oxygen tension baseline blood flow breath changes in Confidence intervals correlated correlation correlation coefficient COVID-19 dead decrease Decreased demonstrated effective End-Expiratory Pressure facilitate feasibility fraction group increase in instantaneous less lung Lung perfusion Lung volume mean difference Mechanical mechanical ventilation mechanically ventilated patient moderate monitoring negative correlation non-responder non-responders outcome oxygen Oxygenation P/F P/F ratio Patient Pearson PEEP physiological physiological response Pneumonia Positive end-expiratory pressure positively correlated Primary outcome pulmonary blood flow recruited reported Respiratory failure Responder responders response secondary severe COVID-19 severe respiratory failure statistically to define Ventilation Volume was increased [DOI] 10.1186/s13054-022-04110-0 PMC 바로가기 [Article Type] Observational Study
Glycaemic variability is associated with all-cause mortality in COVID-19 patients with ARDS, a retrospective subcohort study Research Published on 2022-06-142022-10-05 Journal: Scientific Reports [Category] 바이오마커, 임상, 치료법, [키워드] Aachen acute respiratory distress adjusted all-cause mortality ARDS caused clinically cohort study confounders Continuous coronavirus disease COVID-19 COVID-19 mortality COVID-19 patient death diabete diabetes elevated Factor Germany Glucose high mortality ICU ICU admission increase in intensive care Kaplan–Meier estimator likelihood mechanical ventilation median Metrics moderate Mortality mortality risk P/F ratio Patient patients with COVID-19 plasma procalcitonin retrospective severe ARDS significant increase statistically significant difference survival syndrome university Variability with COVID-19 [DOI] 10.1038/s41598-022-13816-8 [Article Type] Research
Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations심각한 COVID-19 3개월 후 호흡기 기능 장애는 장내 미생물 변화와 관련이 있습니다Article Published on 2022-06-012022-09-11 Journal: Journal of internal medicine [Category] COVID19(2023년), SARS, 임상, [키워드] 16S rRNA 16S rRNA gene alteration Analysis analyzed Bacterial carbon monoxide collected coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 patient defined diffusing diffusing capacity disease severity dysfunction elevated Evidence fibrosis FIVE Follow-up gastrointestinal tract Gut gut microbiota gut microbiota composition gut-lung axis Hospital admission Hospitalization Hypothesis Inflammation investigated involved kPa LBP limit lipopolysaccharide low-grade inflammation lung Lungs marker Microbiome microbiota P/F ratio Patient plasma Protein pulmonary dysfunction Pulmonary function Rectal swabs reduced remained respiratory Respiratory failure respiratory infection rRNA SARS-CoV-2 Sequencing severe COVID-19 Swab the disease Trial was collected was reduced [DOI] 10.1111/joim.13458 PMC 바로가기 [Article Type] Article
Low testosterone predicts hypoxemic respiratory insufficiency and mortality in patients with COVID-19 disease: another piece in the COVID puzzle낮은 테스토스테론은 COVID-19 질병 환자의 저산소성 호흡 부전 및 사망률을 예측합니다: COVID 퍼즐의 또 다른 조각Article Published on 2022-04-012022-09-11 Journal: Journal of Endocrinological Investigation [Category] 바이오마커, [키워드] 95% CI 95% confidence interval acute illness acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age association C-reactive protein clinical impact Comorbidities coronavirus coronavirus disease COVID COVID-19 described evaluate evaluated ferritin fraction Hospital stay Hospitalized hypogonadism hypoxemic in-hospital mortality Infection Inflammation inflammatory parameter inflammatory parameters interleukin-6 investigated IRCCS Italy Lactate lactate dehydrogenase male male subject male subjects Mortality mortality rate multivariable Odds ratio Older outcome oxygen P/F ratio PaO partial pressure patients with COVID-19 Pneumonia predict Prevalence Prospective Regression analyses respiratory respiratory insufficiency SARS-CoV-2 SARS-COV-2 infection serum severe acute respiratory syndrome Coronavirus significantly subject syndrome Testosterone thyroid function Ventilation [DOI] 10.1007/s40618-021-01700-7 PMC 바로가기 [Article Type] Article
Comparison between methylprednisolone infusion and dexamethasone in COVID-19 ARDS mechanically ventilated patientsResearch Published on 2022-02-152022-10-31 Journal: The Egyptian Journal of Internal Medicine [Category] COVID-19, [키워드] acute respiratory distress Analysis ARDS Berlin both group caused Chest Clinical outcome coronavirus Coronavirus disease 2019 Corticosteroid Course COVID-19 COVID-19 pneumonia CRP Cytokine storm D-dimer decrease Dexamethasone diagnosed discharge dose effective effective therapy evaluated ferritin fraction Ground glass opacity ICU inclusion criteria Inflammatory marker intensive care intensive care patient invasive mechanical laboratory result LDH less lymphocyte marker material mechanical ventilation mechanically ventilated mechanically ventilated patient Methylprednisolone methylprednisolone group Mortality neutrophil optimal dose overall mortality oxygen oxygen supplementation P/F ratio Patient patients treated Pneumonia polymerase chain Previous studies prospective cohort study Protein radiological radiological finding required Result SARS-CoV-2 SARS-CoV-2 pneumonia Severe COVID-19 pneumonia severity statistically significant Steroids survival syndrome the patient tomography treated Treatment university were given [DOI] 10.1186/s43162-022-00113-z PMC 바로가기 [Article Type] Research
Correlation of non-invasive oxygenation parameters with paO2/FiO2 ratio in patients with COVID-19 associated ARDSArticle Published on 2022-02-012023-07-07 Journal: European journal of internal medicine [Category] COVID19(2023년), [키워드] ARDS COVID-19 P/F ratio ROX index S/F ratio. [DOI] 10.1016/j.ejim.2021.12.015 PMC 바로가기
Is There a Crucial Link Between Vitamin D Status and Inflammatory Response in Patients With COVID-19?COVID-19 환자의 비타민 D 상태와 염증 반응 사이에 중요한 연관성이 있습니까?Clinical Trial Published on 2022-01-242022-09-12 Journal: Frontiers in Immunology [Category] 임상, 진단, [키워드] 25OHD 25OHD level 25OHD levels adjusted age and sex biochemical Clinical data cohort of patient Complete consecutive patient coronavirus disease correlation COVID-19 CRP Cytokine storm D-dimer Effect evaluate evaluated group hospital Hospitalization hypovitaminosis Hypovitaminosis D IL-10 IL-6 Infection Inflammatory marker inflammatory markers inverse correlation management marker non-survivor P/F ratio Patient patients Pneumonia poor prognosis prevalent response Result risk factor SARS-CoV-2 secondary endpoint severe ARDS severity significantly higher status suggested the disease TNF-α Vitamin D Vitamin D status with COVID-19 [DOI] 10.3389/fimmu.2021.745713 PMC 바로가기 [Article Type] Clinical Trial