Integrative analyses of genes about venous thromboembolism: An umbrella review of systematic reviews and meta-analysesArticle Published on 2022-10-282022-11-16 Journal: Medicine [Category] meta-analysis, 변종, [키워드] activating analysis Analysis appraisal checklist conducted COVID-19 vaccination criteria Critical cumulative database Effect effect size eligible endothelial environmental risk factor Epidemiology estimates etiology Evidence Genetic genetic risk factor Genetic variant Genetic variations had more heterogeneity Human identify Intervention meta-analyses meta-analysis MTHFR network p values performed polymorphism protease Protein prothrombin provided receptor respond review risk Risk factors Sample size selected surgical systematic review variable variant Venice venous Venous Thromboembolism VTE was performed were used [DOI] 10.1097/MD.0000000000031162 PMC 바로가기
Who is hesitant about Covid-19 vaccines? The profiling of participants in a French online cohort누가 Covid-19 백신에 대해 주저합니까? 프랑스 온라인 코호트 참가자 프로파일링Article Published on 2022-06-012022-09-11 Journal: Revue d'épidémiologie et de santé publique [Category] COVID19(2023년), SARS, 치료기술, [키워드] analysis carried Characteristics Cohort Cohorte continuum COVID-19 Descriptive statistics detect English fake news female flu French grippe groups Health Hesitancy Hésitation vaccinale identify Inclusion individual less multinomial regression multivariate analyses multivariate analysis Odds ratio Odds ratios p values pandemic participant Participants predictor predictors presenting Profil Profiling proportion public health authorities public health authority SARS-CoV-2 SARS-CoV-2 pandemic the SARS-CoV-2 Treatment undergo vaccination Vaccine Vaccine hesitancy vaccine hesitancy. vaccine-hesitant Vaccines variable variant while women [DOI] 10.1016/j.respe.2022.02.004 PMC 바로가기 [Article Type] Article
GraphOmics: an interactive platform to explore and integrate multi-omics data그래픽학 : 다중 생물 데이터를 탐색하고 통합하는 대화식 플랫폼Software Published on 2021-12-182022-09-10 Journal: BMC Bioinformatics [Category] 유전자 메커니즘, [키워드] Analysis biochemical can be used case study Clustering common reaction complex complexity computational method Data exploration dataset demonstrated difficulty examined filtered Fold changes heatmap hypothese Hypothesis information mapped metabolomics Omics integration p values pathway Pathway analysis Pathways performed platform proteomics reaction Reactions Reactome Result selected statistical significance Support transcriptomics user Visualisation was used while [DOI] 10.1186/s12859-021-04500-1 PMC 바로가기 [Article Type] Software
Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strainSARS-CoV-2 게놈에서 COVID-19 사망률 위험에 대한 게놈 차원의 연관성 분석은 브라질 균주의 P.1과 함께 국소화되는 SARS-CoV-2 스파이크 단백질의 돌연변이를 식별합니다Article Published on 2021-10-012022-09-11 Journal: Genetic epidemiology [Category] SARS, 변종, 치료기술, 치료제, [키워드] Affect Alter Amino acid analyses Analysis analyzed approach association Brazil can not center change coding sequences Containment Control COVID-19 mortality COVID-19 patient database databases defined disease control driven by ENhance Follow-up Frequency Genome-wide association studies Genome-wide association study genome-wide significance geographical regions GISAID GISAID database GWAS highly pathogenic host susceptibility identify improvement Improvements in viral information loci locus Logistic Logistic regression methodology Mortality Mutation occur p value p values P.1 pathogenic pathogenicity remained risk S2 subunit SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 spike protein sequence variation sequenced single-stranded Spike protein starting strain submitted symptom severity target host cells the SARS-CoV-2 the SARS-CoV-2 genome variant viral entry viral genome viral infectivity viral strain virus WGS whole-genome sequencing Whole-genome sequencing. [DOI] 10.1002/gepi.22421 PMC 바로가기 [Article Type] Article
Development of in-house, indirect ELISAs for the detection of SARS-CoV-2 spike protein-associated serology in COVID-19 patients in Panama파나마의 COVID-19 환자에서 SARS-COV-2 스파이크 단백질 관련 혈청학의 검출을위한 사내, 간접 ELISA의 개발Research Article Published on 2021-09-142022-09-10 Journal: PLoS ONE [Category] 진단, 치료기술, [키워드] acute respiratory disease Analysis analyzed antibodies Antigen antigens AUC caused comparison confirmation Contact contact with coronavirus COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients Cross reactivity Cutoff Definition detect development diagnostic diagnostic test effective ELISA ELISA assay estimation evaluate fragment health authorities Health authority Human IgG IgG and IgM IgM IgM antibodies IMPROVE MERS morbidity Mortality Multiple multiple comparisons name New coronavirus new coronavirus SARS-CoV-2 no significant difference OD values outbreak p values parameter PCR produced Protein reactivity real time real time PCR receiver operating characteristic Receptor binding domain Respiratory disease reverse transcriptase RT-PCR RT-PCR test SARS-CoV-2 SARS-CoV-2 spike sensitivity serology Seroprevalence serum sample specificity spike Spike protein Strong symptomatic individual symptomatic individuals the antibody Viral viral antigens Viral RNA viral spike protein virus [DOI] 10.1371/journal.pone.0257351 PMC 바로가기 [Article Type] Research Article
Impact of delay in cystoscopic surveillance on recurrence and progression rates in patients with non-muscle-invasive bladder cancer during the COVID-19 pandemicCOVID-19 대유행 기간 동안 비근육 침습성 방광암 환자의 재발 및 진행률에 대한 방광경 감시 지연의 영향Article Published on 2021-09-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 치료기술, [키워드] 105 patient 105 patients analysis Analysis applied bladder Bladder cancer Characteristics COVID-19 pandemic cystoscopy demographics Disease progression evaluate Factor fold Follow-up GRADE Impact increase Logistic regression analysis material multivariate Multivariate analysis multivariate logistic regression analysis p values pathology Patient Primary outcome Probability progression recurrence risk risk factor schedule Stage Surveillance transurethral resection was performed were recorded [DOI] 10.1111/ijcp.14490 PMC 바로가기 [Article Type] Article
Leveraging Transfer Learning to Analyze Opinions, Attitudes, and Behavioral Intentions Toward COVID-19 Vaccines: Social Media Content and Temporal Analysis전이 학습을 활용하여 COVID-19 백신에 대한 의견, 태도 및 행동 의도 분석: 소셜 미디어 콘텐츠 및 시간 분석Original Paper Published on 2021-08-102022-09-10 Journal: Journal of Medical Internet Research [Category] MERS, SARS, 치료기술, [키워드] 95% CI acceptance addition alleviate Analysis approach automatically can be used changed collected content content analysis COVID-19 COVID-19 vaccine COVID-19 vaccines dataset detect educational programs effective followed by infodemiology infoveillance Intention Intervention latent Dirichlet allocation learning leveraging transfer learning Logistic regression machine learning machine learning model machine learning models media objective online health p value p values pandemic positive Prevalence Primary outcome promote provided public health random Random forest Result selected significantly social media statistical Support support vector machine Temporal Temporal analysis Topic transfer unique Vaccine were used [DOI] 10.2196/30251 PMC 바로가기 [Article Type] Original Paper
COVID-19 Cases from the First Local Outbreak of the SARS-CoV-2 B.1.1.7 Variant in China May Present More Serious Clinical Features: A Prospective, Comparative Cohort StudySARS-CoV-2 B.1.1.7 변종 중국의 첫 번째 지역 발병으로 인한 COVID-19 사례가 더 심각한 임상 특징을 나타낼 수 있음: 전향적, 비교 코호트 연구Research Article Published on 2021-08-042022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 치료기술, 치료제, [키워드] acute response age amyloid A B.1.1.7 B.1.1.7 variant Beijing C-reactive protein caused CD4 China clinical Clinical characteristics clinical feature Clinical features Clinical tests Comparative conducted contagious COVID-19 COVID-19 case COVID-19 cases COVID-19 outbreak COVID-19 patient COVID-19 patients creatine creatine kinase CRP d -dimer database diagnoses dimer District elevated Epidemics Features Fever GGO ground-glass opacity Infection Inflammatory response knowledge lead lung Lymphocytes median N gene occurred outbreak p value p values pathogenicity Pneumonia present proportion Prospective quantitative PCR reported reverse transcriptase risk factor RT-qPCR SAA SARS-CoV-2 SARS-CoV-2 B.1.1.7 SARS-CoV-2 strain serum amyloid severe pneumonia significantly higher significantly lower T lymphocyte T lymphocytes The B.1.1.7 the SARS-CoV-2 threshold transcriptase Transmission triggered United Kingdom variant Viral Viral load viral loads whole-genome analysis [DOI] 10.1128/Spectrum.00273-21 PMC 바로가기 [Article Type] Research Article
Effects of different types of written vaccination information on COVID-19 vaccine hesitancy in the UK (OCEANS-III): a single-blind, parallel-group, randomised controlled trial영국(OCEANS-III)의 COVID-19 백신 주저에 대한 다양한 유형의 서면 예방 접종 정보의 영향: 단일 맹검, 병렬 그룹, 무작위 대조 시험Articles Published on 2021-05-132022-08-13 Journal: The Lancet. Public Health [Category] 임상, [키워드] 95% CI addition addressed adjusted Adults Alter analysed assigned benefit Combination condition confidence control condition Controlled trial COVID-19 COVID-19 vaccination COVID-19 vaccination programme COVID-19 vaccine COVID-19 vaccines Decision making Effect effective Effectiveness Efficacy and safety engage Ethnicity finding funding Gender greater group Health health campaigns Hesitancy highlight information ISRCTN less mean difference moderate multiple comparisons National Health Service NIHR NIHR Oxford Health Biomedical Research Centre outcome outcome measure outcomes Oxford Oxford Biomedical Research Centre Oxford COVID-19 Vaccine Hesitancy Scale Oxford Vaccine Confidence and Complacency Scale p values pandemic parallel-group participant Perception Primary outcome public health communications randomised controlled trial Randomly recruit recruited recruitment reduce reduced Registered risk scale seriousness single-blind speed stratified terrain vaccination Vaccine Vaccine hesitancy vaccine hesitancy scale vaccine-hesitant virus was reduced [DOI] 10.1016/S2468-2667(21)00096-7 PMC 바로가기 [Article Type] Articles
Single-cell analysis of angiotensin-converting enzyme II expression in human kidneys and bladders reveals a potential route of 2019 novel coronavirus infection인간의 신장과 방광에서 안지오텐신 전환 효소 II 발현의 단일 세포 분석은 2019년 신종 코로나바이러스 감염의 잠재적 경로를 보여줍니다Article Published on 2021-04-202022-09-11 Journal: Chinese medical journal [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] 2019 novel coronavirus 2019-nCoV 2019-nCoV infection ACE2 ACE2 expression ACE2 gene Acute kidney injury acute respiratory syndrome addition Analysis angiotensin Angiotensin-converting enzyme bioinformatics bladder Cell cell type cells co-expression coronavirus disease Coronavirus disease 2019 datasets detectable enzyme II epithelial cells evaluate Evidence evidence of expression Fever healthy house human kidney in urine independent Infection intermediate cell kidney kidney damage nCoV Novel coronavirus p value p values Patient Pearson correlation Pearson correlation coefficient provided proximal proximal convoluted tubule proximal tubule recent findings receptor Respiratory complications reveal SAME AS sequencing data Severe acute respiratory syndrome single-cell analysis Single-cell RNA sequencing subtype urinary system Urine virus [DOI] 10.1097/CM9.0000000000001439 PMC 바로가기 [Article Type] Article