Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and PangolinArticle Published on 2023-04-252023-06-22 Journal: mBio [Category] 조류인플루엔자, [키워드] bat pangolin Risk assessment Severe acute respiratory syndrome-related coronavirus zoonosis. [DOI] 10.1128/mbio.03285-22 PMC 바로가기
Human parainfluenza 3 and respiratory syncytial viruses detected in pangolins천산갑에서 검출된 인간 파라인플루엔자 3 및 호흡기 세포융합 바이러스Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 치료기술, [키워드] approaches died Diseases eight Evidence Host hRSV Human human parainfluenza virus human respiratory diseases identity Infection investigated metagenomic metagenomic sequencing nucleotide Other respiratory viruses pangolin pangolins parainfluenza parainfluenza virus Paramyxoviridae pathogen Pathogens Phylogenetic tree Pneumonia Prevent public health related viruses respiratory diseases respiratory syncytial virus respiratory syncytial virus B respiratory viruses sequence susceptible Symptom Viral transmission virus virus virus transmission virus transmission vector whole-genome zoonotic zoonotic diseases. [DOI] 10.1080/22221751.2022.2086071 PMC 바로가기 [Article Type] Article
Insertion/deletion hotspots in the Nsp2, Nsp3, S1, and ORF8 genes of SARS-related coronavirusesArticle Published on 2022-10-282022-11-16 Journal: BMC Ecology and Evolution [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome animal hosts base bases bat bat coronavirus benefit Characteristics classical complex coronavirus determine Frame Future Genome genomic region hotspot Human human SARS-CoV-2 human SARS-CoV-2 strain INDEL Indel hotspot indels insertion/deletion insertion/deletion (indel). mechanism Multiple sequence alignment Mutation N-terminal domain Neutral non-structural protein Occurrence offer ORF8 ORF8 gene pangolin Pangolin coronavirus (PCoV) Point mutation RaTG13 Region reported RNA sequence S1 domain SARS-CoV SARS-CoV-2 SARS-related coronavirus SARS-related coronaviruses severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) survival the spike protein viral evolution virus virus viruses [DOI] 10.1186/s12862-022-02078-7 PMC 바로가기
SARS-COV-2/COVID-19: scenario, epidemiology, adaptive mutations, and environmental factorsArticle Published on 2022-10-012022-11-16 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), SARS, 변종, [키워드] adaptive bat contaminated surface coronavirus COVID-19 droplet environmental factor environmental factors Epidemiology Evolution explain Genetic globe Health threat human infection human-to-human transmission humans involved key factor mortality rate mutations origin overcome pandemic pangolin pathogen predicted SARS-CoV-2 SARS-CoV-2 variant Transmission variants. virus while worldwide pandemic [DOI] 10.1007/s11356-022-22333-0 PMC 바로가기
A Study on the Nature of SARS-CoV-2 Using the Shell Disorder Models: Reproducibility, Evolution, Spread, and AttenuationArticle Published on 2022-09-232022-11-16 Journal: Biomolecules [Category] SARS, 변종, [키워드] applied attenuation bat-CoV contagiousness coronavirus Coronaviruses correlated CoV COVID COVID-19 demonstrated disorder enzyme greater Hard immune system implication intrinsic Long COVID lung membrane protein Nature nucleocapsid protein nucleoprotein observation omicron pangolin Particle PID predicted PROTECT Replication Saliva SARS-CoV-2 shell supported tissues transmissions variant Viral load virion virulence virulence. virus [DOI] 10.3390/biom12101353 PMC 바로가기
Genomic and Epidemiological Features of COVID-19 in the Novosibirsk Region during the Beginning of the PandemicArticle Published on 2022-09-142022-11-16 Journal: Viruses [Category] SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] Analysis Asymptomatic B.1 B.1.1 center children conducted Contact COVID-19 D614G substitution diagnostic tests Epidemiology First wave Genome sequences had no highest individual isolate Lineage Medicine Mutation pandemic pangolin patients with COVID-19 Phylogenetic Phylogeny phylogeny. positive positive sample Protein Region retrospective Russia SARS-CoV-2 SARS-CoV-2 sequencing single-center study tested the SARS-CoV-2 the Spike variant [DOI] 10.3390/v14092036 PMC 바로가기
Whole-genome sequencing of SARS-CoV-2 reveals diverse mutations in circulating Alpha and Delta variants during the first, second, and third waves of COVID-19 in South Kivu, east of the Democratic Republic of the CongoResearch article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] A.23.1 Analysis B.1.351 B.1.617.2 circulating circulation coding sequence consensus genome COVID-19 D614G Delta delta variant Diagnosis disease severity dominant Genes Genetic evolution Genetic variation genome coverage genomic global pandemic highlight identify include information isolate Lineage management mapped molecular MOST Mutation nucleocapsid protein objective ORF1ab ORF3 outbreak Oxford P.1 pandemic pangolin Phylogenetic analysis Point mutation processed reference genome responsible Result reveal SARS-CoV-2 SARS-CoV-2 isolate sequence sequenced Sequencing Seven South South Kivu subsequent Surveillance synonymous the SARS-CoV-2 genome Treatment variant variants were used whole-genome sequencing Wuhan [DOI] 10.1016/j.ijid.2022.05.041 [Article Type] Research article
Origin of novel coronavirus causing COVID-19: A computational biology study using artificial intelligenceResearch article Published on 2022-09-012022-10-05 Journal: Machine Learning with Applications [Category] 변종, [키워드] AI Algorithm analysed Analysis artificial intelligence bat caused Cluster Clustering collected coronavirus genomes country COVID-19 COVID-19 virus death disease Evidence examined experiment genome sequence genomic genomic sequence global pandemic Host hypothese infected case machine learning Novel coronavirus origin pandemic pangolin pangolins provide recent Research SARS-CoV-2 SARS-CoV-2 genome Scientific community the SARS-CoV-2 virus whole genome [DOI] 10.1016/j.mlwa.2022.100328 [Article Type] Research article
Cross-Neutralization of SARS-CoV-2-Specific Antibodies in Convalescent and Immunized Human Sera against the Bat and Pangolin Coronaviruses박쥐 및 천산갑 코로나바이러스에 대한 회복기 및 면역화된 인간 혈청에서 SARS-CoV-2-특이적 항체의 교차 중화Article Published on 2022-08-162022-09-12 Journal: Viruses [Category] SARS, 진단, [키워드] ACE2 analyzed appear bat bat coronavirus binding Cell cell-cell fusion chimeric chimeric proteins contribute coronavirus COVID-19 COVID-19 patient cross-neutralize highest Human human ACE2 receptor human host immunized inactivated induce less neutralization neutralization activity neutralized Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody overexpressing pandemic pangolin pangolin coronavirus pangolins pre-existing immunity promote Protein pseudo-virus pseudo-virus. RaTG13 RBD replaced sarbecovirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine serum sample significantly significantly higher spike the RBD the receptor-binding domain thought transmitted vaccination VeroE6 cells while widespread [DOI] 10.3390/v14081793 PMC 바로가기 [Article Type] Article
Variation in synonymous nucleotide composition among genomes of sarbecoviruses and consequences for the origin of COVID-19사베코바이러스 게놈 간 동의 염기 조성의 변이와 코로나19의 기원에 대한 영향Article Published on 2022-08-152022-09-11 Journal: Gene [Category] COVID19(2023년), SARS, 치료기술, [키워드] analysed bat bat virus Bulgaria China Codons consequence coronavirus COVID-19 COVID-19 pandemic cytosine degenerate diagnosed dinucleotides distribution eight Evidence evidence of explain feature FIVE Genome genomes group horseshoe bat Host host cell host cells include independent intermediate intermediate host Japan Kenya less Manis javanica mutations nucleotide pangolin pangolins RdRP RdRp selection Recombination reservoir Reservoir host responsible sarbecovirus sarbecovirus Sarbecoviruses SARS epidemic SARS-CoV SARS-CoV-2 subgenus synonymous Synonymous mutations. the SARS epidemic uracil viral replication viruses [DOI] 10.1016/j.gene.2022.146641 PMC 바로가기 [Article Type] Article