Racial and Ethnic Disparities in Outpatient Treatment of COVID-19 – United States, January-July 2022Article Published on 2022-10-282022-11-15 Journal: Morbidity and Mortality Weekly Report [Category] 치료제, [키워드] African American Alaska Antiviral Antiviral treatment antivirals Asian black booster doses Care COVID-19 COVID-19 in patient COVID-19 patient COVID-19 treatments COVID-19 vaccination disparity drug EHR Emergency use authorization EUA facilitate food Health help high risk highest Hispanic patient Immunocompromised less mAb medication Mild-to-moderate molnupiravir monoclonal antibody Native outcomes Outpatient Patient patient groups patients Paxlovid PROTECT Racial Remdesivir report risk seeking severe COVID-19 treated Treatment United States were used White patients [DOI] 10.15585/mmwr.mm7143a2 PMC 바로가기
Self-collection of capillary blood and saliva to determine COVID-19 vaccine immunogenicity in patients with immune-mediated inflammatory diseases and health professionalsArticle Published on 2022-10-142022-11-15 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 진단, [키워드] Accuracy analyzed antibodies Antibody Response being Blood blood collection both group capillary capillary blood Clinical practice collected correlation coefficient COVID-19 COVID-19 vaccine criteria determine dose effective evaluate feasibility feasible flexible Health Immune-mediated inflammatory disease less majority NPs participant Patient patient groups professional promoter protocol recorded Remote care reported Safe Saliva SARS-CoV-2 antibody response SARS-CoV-2 vaccines self-collection Self-sampling significantly significantly higher Spearman SUS telehealth Usability vaccination Vaccination strategy Vaccine venous Wilcoxon signed-rank test [DOI] 10.3389/fpubh.2022.994770 PMC 바로가기
Serum of Post-COVID-19 Syndrome Patients with or without ME/CFS Differentially Affects Endothelial Cell Function In VitroME/CFS가 있거나 없는 포스트 코로나19 증후군 환자의 혈청은 체외 내피 세포 기능에 차등적으로 영향을 미칩니다Article Published on 2022-08-022022-09-11 Journal: Cells [Category] 바이오마커, [키워드] Activation analysed Angiogenesis autoantibodies autoantibody binding Cell chronic fatigue syndrome compensatory mechanism COVID-19 Cytokines demonstrated develop Diagnostic Criteria dysregulated Effect Encephalomyelitis endothelial endothelial cells Endothelial dysfunction fatigue fatigue syndrome flow cytometry function functional groups healthy control healthy controls hypothesise in vitro investigated involved marker mechanism molecules Myalgic encephalomyelitis/chronic fatigue syndrome nitric oxide Patient patient cohort patient group patient groups patients post-COVID syndrome profile promoted proportion reduced screened secretion sera serum serum cytokines significantly significantly increased small molecule Small molecules syndrome vascular remodelling was measured while [DOI] 10.3390/cells11152376 PMC 바로가기 [Article Type] Article
Circulating B10 regulatory cells are decreased in severe and critical COVID-19심각하고 치명적인 COVID-19에서 순환하는 B10 조절 세포가 감소합니다Article Published on 2022-08-012022-09-11 Journal: Journal of leukocyte biology [Category] COVID19(2023년), SARS, 치료기술, [키워드] B cell B cells B10 Bregs Cell cells clinical and laboratory parameters correlated COVID-19 COVID-19 pathogenesis Critical critical COVID-19 patient determine disease severity evaluate Evidence explained Frequency functional healthy individuals IL-10 immune response immune responses include inflammatory parameter Laboratory parameters mechanisms multiparametric flow cytometry patient groups PBMC PBMCs reduction in Regulatory regulatory cell SARS-CoV-2 severity specific antibodies specific antibody Stimulation subset the disease [DOI] 10.1002/JLB.5COVCRA0721-387RR PMC 바로가기 [Article Type] Article
Cellular and humoral immune response to SARS-CoV-2 vaccination and booster dose in immunosuppressed patients: An observational cohort study면역억제 환자에서 SARS-CoV-2 예방접종 및 추가 용량에 대한 세포 및 체액 면역 반응: 관찰 코호트 연구Observational Study Published on 2022-08-012022-09-12 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Ad26.COV2.S anti-CD20 anti-SARS-CoV-2 S1 IgG B cell BNT162b2 booster booster dose booster vaccination Cellular immune response cellular immunity cellular response clinical COVID-19 defined ELISA Factor Healthcare system humoral humoral immune response IgG IGRA Immunosuppressed immunosuppressed patient Immunosuppression individual interferon gamma lymphoma median age monoclonal antibody mRNA-1273 Observational cohort study Patient patient groups performed populations positive receptor retrospective SARS-CoV-2 SARS-CoV-2 vaccination serology significantly higher sphingosine vaccination vaccine response variable were measured [DOI] 10.1016/j.jcv.2022.105217 PMC 바로가기 [Article Type] Observational Study
Low tidal volume ventilation is associated with mortality in COVID-19 patients-Insights from the PRoVENT-COVID studyObservational Study Published on 2022-08-012022-10-04 Journal: Journal of critical care [Category] 임상, [키워드] 28-day mortality acute respiratory distress addition Analysis ARDS association clinician Cohort Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients defined disease Factor First wave help initial investigated median Mortality National not different pandemic paralysis Patient patient groups patients predicted primary endpoint receive receiving recognize reduced risk secondary Severity Score syndrome Tidal volume Ventilated Ventilation Volume [DOI] 10.1016/j.jcrc.2022.154047 PMC 바로가기 [Article Type] Observational Study
Neurological long-COVID in the outpatient clinic: Two subtypes, two coursesResearch article Published on 2022-08-012022-10-05 Journal: Journal of the neurological sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute COVID-19 acute infection acute phase Ageusia Analysis analyzed Anosmia average BMI Characteristics Clinical data Cluster Clustering analysis collected Complication Course COVID 19 COVID-19 COVID-19 infection COVID-19 symptoms evaluated Evidence Follow-up headache Hospitalization identify impairment Infection Intervention Linear regression analysis Logistic long-COVID memory nervous system neurological Neurological involvement Neurological symptom nine number of comorbidity outpatient clinic Patient patient group patient groups performed Post-COVID neurological symptoms Psychological reported symptom Result returned Risk factors severity subject subtype Subtypes Symptom Treatment variable [DOI] 10.1016/j.jns.2022.120315 [Article Type] Research article
Association Between SARS-CoV-2 Messenger RNA Vaccines and Lower Infection Rates in Kidney Transplant Recipients : A Registry-Based ReportObservational Study Published on 2022-07-012022-10-04 Journal: Annals of internal medicine [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI adjusted association Characteristics clinical Czech Republic Department Follow-up incidence rate kidney transplant recipient Lower lower risk Medicine messenger Messenger RNA Ministry of Health mRNA mRNA vaccination multivariable Nephrology Observational cohort study patient groups polymerase chain provided Rate recipient remains uncertain report risk RNA SARS-CoV-2 SARS-COV-2 infection Transplant vaccination Vaccine [DOI] 10.7326/M21-2973 PMC 바로가기 [Article Type] Observational Study
Digital medical history implementation to triage orthopaedic patients during COVID-19: Findings from a rapid cycle, semi-randomised A/B testing quality improvement projectCOVID-19 동안 심각한 정형 외과 환자에게 디지털 병력 구현 : 빠른주기, 반 랜가이션 A/B 테스트 품질 개선 프로젝트에서 결과Randomized Controlled Trial Published on 2022-06-012022-08-31 Journal: Musculoskeletal care [Category] MERS, 임상, 치료제, [키워드] A/B testing age analysed approach Care clinic clinic visit collected completion rate conducted COVID-19 COVID-19 pandemic crisis Descriptive statistics determine Digital digital medical history finding FIVE Health Health care health care transformation health information helping highest impacted implementation improvement increasing age Injury Intensive Intervention Logistic regression medical history multivariable logistic regression Musculoskeletal musculoskeletal care notable Odds ratio Patient patient groups patients Quality Quality improvement randomised resource the patient unique utilised value-based health care. was used were used [DOI] 10.1002/msc.1605 PMC 바로가기 [Article Type] Randomized Controlled Trial
Viral Antigen and Inflammatory Biomarkers in Cerebrospinal Fluid in Patients With COVID-19 Infection and Neurologic Symptoms Compared With Control Participants Without Infection or Neurologic Symptoms감염 또는 신경학적 증상이 없는 대조군과 비교하여 COVID-19 감염 및 신경학적 증상이 있는 환자의 뇌척수액에서 바이러스 항원 및 염증성 바이오마커Article Published on 2022-05-022022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, 치료법, [키워드] 95% CI age Antigen Biomarker capture Central nervous system cerebrospinal fluid clinical CNS component Concentration contribute Control control group controls correlated COVID COVID-19 COVID-19 infection COVID-19 severity cross-sectional cross-sectional study CSF Cytokines detectable disease severity Encephalopathy Evidence evidence of Gothenburg Health Organization healthy control highlight IL-10 IL-6 immune activation immune response immune responses immunoassay Infection Inflammatory Inflammatory biomarker inflammatory biomarkers Injury interferon interferon γ interleukin IQR male median microglobulin moderate Moderate COVID-19 Necrosis neurologic neuronal no differences nucleocapsid antigen Older outcome participant Participants Pathogenesis Patient patient groups platform Principal component principal component analysis Protein Sahlgrenska University Hospital SARS-COV-2 infection SARS-CoV-2 nucleocapsid scale severe COVID-19 severe disease significantly significantly higher Study protocol Swedish Symptom Symptoms test results Tumor tumor necrosis tumor necrosis factor tumor necrosis factor α Viral Viral antigen viral invasion Viral RNA was performed with COVID-19 World Health Organization β2-microglobulin [DOI] 10.1001/jamanetworkopen.2022.13253 PMC 바로가기 [Article Type] Article