PD‐1 – Communicable Diseases Research

TIM‐3 as a potential exhaustion marker in CD4 + T cells of COVID‐19 patients

COVID-19 환자의 CD4 + T 세포에서 잠재적인 피로 마커로서의 TIM-3

Original Article

Published on 2021-09-092022-09-10
Journal: Immunity, Inflammation and Disease
[Category] SARS, 치료기술,

[키워드] Blood Blood urea nitrogen C‐reactive protein calculated cause CD39 CD4 clinical information clinical symptom Clinical symptoms collected COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 creatinine Critical critical patients deaths disease erythrocyte sedimentation erythrocyte sedimentation rate evaluate evaluated Exhausted cell flow cytometry group groups healthy individuals in healthy individual laboratory data lymphocyte Lymphocytes lymphopenia marker Mild mononuclear cell mononuclear cells neutrophil neutrophil count nitrogen occur overexpression Patient patient groups PBMCs PD‐1 PD‐1 peripheral Peripheral blood Peripheral blood mononuclear cells Result sedimentation rate significant difference significantly higher subjects subpopulation T cell T cells TIM‐3 urea
[DOI] 10.1002/iid3.526 PMC 바로가기 [Article Type] Original Article

COVID‐19, varying genetic resistance to viral disease and immune tolerance checkpoints

코로나19, 바이러스성 질병에 대한 다양한 유전적 저항성과 면역관용 체크포인트

Review

Published on 2020-11-232022-09-10
Journal: Immunology and Cell Biology
[Category] Fulltext, MERS, SARS, 유전자 메커니즘, 조류인플루엔자, 진단,

[키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive adaptive immune responses America antibody Antibody responses Asymptomatic CD8 T cell CD8 T cells cGAS colonization core coronavirus coronavirus disease Coronavirus disease 2019 COVID‐19 cowpox crisis CTLA‐4 difference Genes Genetic genetic mechanism genetic resistance genomic technology Human immunodeficiency virus immune immune responses immune tolerance Infection Influenza interferon knowledge lethal limit MARK mechanism myxoma neutralizing antibody responses outcome pandemic parameter pathology PD‐1 plague problem problems pyroptosis respiratory responsible SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus smallpox T cells threshold TNFAIP3 Tolerance Vaccine Viral viral disease virus virus virus transmission viruses zoonose zoonoses zoonosis
[DOI] 10.1111/imcb.12419 PMC 바로가기 [Article Type] Review