Expanded profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39스트렙토코쿠스 뉴모니아 D39에서 페니실린 결합 단백질에 대한 β-락탐 선택성의 확장된 프로파일링Article Published on 2022-02-282024-08-24 Journal: Biological Chemistry [Category] 폐렴구균 감염증, [키워드] activity-based probes Antibiotics penicillin-binding proteins β-lactams
Integrative Reverse Genetic Analysis Identifies Polymorphisms Contributing to Decreased Antimicrobial Agent Susceptibility in Streptococcus pyogenes통합 역유전 분석이 Streptococcus pyogenes에서 항균제 감수성 감소에 기여하는 다형성을 식별하다Research Article Published on 2022-01-182024-07-30 Journal: mBio [Category] 폐렴구균 감염증, [키워드] Antibiotic resistance beta-lactams molecular evolution penicillin-binding proteins population genomics Positive selection Streptococcus pyogenes whole-genome sequencing β-lactams [DOI] 10.1128/mbio.03618-21 PMC 바로가기 [Article Type] Research Article
Resistance to β-lactams in Streptococcus pneumoniaearticle Published on 2021-09-302024-09-01 Journal: Rev Argent Microbiol [Category] 폐렴구균 감염증, [키워드] penicillin-binding proteins Proteínas ligadoras de penicilina resistance Resistencia Streptococcus pneumoniae β-Lactámicos β-lactams [Article Type] article
Analysis of Amino Acid Sequences of Penicillin-Binding Proteins 1a, 2b, and 2x in Invasive Streptococcus pneumoniae Nonsusceptible to Penicillin Isolated from Children in Indiaarticle Published on 2021-03-312024-09-01 Journal: Microbial Drug Resistance [Category] 폐렴구균 감염증, [키워드] India invasive penicillin nonsusceptible S. pneumoniae penicillin-binding proteins [Article Type] article
Chemical tools for selective activity profiling of bacterial penicillin-binding proteinsarticle Published on 2020-12-312024-09-01 Journal: Membrane Proteins—Production and Functional Characterization [Category] 폐렴구균 감염증, [키워드] activity-based probes activity-based protein profiling Chemical microbiology Chemical probe design chemical probes Electrophilic center penicillin-binding proteins super-resolution fluorescence microscopy β-Lactones [Article Type] article
A CozE Homolog Contributes to Cell Size Homeostasis of Streptococcus pneumoniae코즈E 동종체가 폐렴구균의 세포 크기 항상성에 기여한다.Article Published on 2020-10-272024-07-30 Journal: mBio [Category] 폐렴구균 감염증, [키워드] cell division morphogenesis penicillin-binding proteins peptidoglycan [DOI] 10.1128/mBio.02461-20 PMC 바로가기
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery박테리아 세포 신장 기계에 의한 펩티도글리칸 중합의 활성화에서 PBP2의 중심 역할Research Article Published on 2018-10-182022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin activate activated Activation activation pathway activities activity Analysis antibiotic Author Bacteria bacterial cell biogenesis Cell Cell elongation cell wall cell wall synthesis changes in complex complexes component conserved Control control cell crosslinking cytokinesis cytoskeletal filament cytoskeletal filaments determine disrupt enzymatic activity enzyme Enzymes Escherichia coli Evidence exhibited Genetic genetic evidence glycan glycan polymerase glycan polymerases hyperactivate identify in vitro in vivo inactivated morphogenic MreB Mutation osmotic lysis pathway PBP PBP2 PBPs penicillin penicillin-binding protein penicillin-binding proteins polymerase Prevent promote PROTECT provide remained required Rod system RodA stimulate the cell uncrosslinked variant [DOI] 10.1371/journal.pgen.1007726 PMC 바로가기 [Article Type] Research Article
Analysis of amino acid motif of penicillin-binding proteins 1a, 2b, and 2x in invasive Streptococcus pneumoniae nonsusceptible to penicillin isolated from pediatric patients in Casablanca, Morocco소아 환자에게서 분리된 페니실린 비감수성 침습성 폐렴구균의 페니실린 결합 단백질 1a, 2b 및 2x의 아미노산 모티프 분석, 모로코 카사블랑카에서Research Note Published on 2018-08-312024-07-31 Journal: BMC Research Notes [Category] 폐렴구균 감염증, [키워드] pbp gene penicillin resistance penicillin-binding proteins serotypes Streptococcus pneumoniae β-lactams [DOI] 10.1186/s13104-018-3719-5 PMC 바로가기 [Article Type] Research Note
Comparative genomic analysis of ten clinical Streptococcus pneumoniae collected from a Malaysian hospital reveal 31 new unique drug-resistant SNPs using whole genome sequencing말레이시아 병원에서 수집된 10개의 임상 Streptococcus pneumoniae에 대한 비교 유전체 분석 결과, 전체 유전체 시퀀싱을 사용하여 31개의 새로운 고유 약물 내성 SNP가 발견되었습니다.Research Published on 2018-02-152024-08-01 Journal: Journal of Biomedical Science [Category] 폐렴구균 감염증, [키워드] Antibiotic-resistance penicillin-binding proteins Single nucleotide polymorphism Streptococcus pneumoniae Whole genome sequencing [DOI] 10.1186/s12929-018-0414-8 PMC 바로가기 [Article Type] Research
A Specialized Peptidoglycan Synthase Promotes Salmonella Cell Division inside Host Cells전문화된 펩타이드글리칸 합성효소가 숙주 세포 내에서 살모넬라 세포 분열을 촉진한다.Research Article Published on 2017-12-192024-07-29 Journal: mBio [Category] 살모넬라증, [키워드] cell division intracellular pathogens penicillin-binding proteins peptidoglycan Salmonella [DOI] 10.1128/mBio.01685-17 PMC 바로가기 [Article Type] Research Article