Thromboses and Hemostasis Disorders Associated with COVID-19: The Possible Causal Role of Cross-Reactivity and Immunological ImprintingOriginal Article Published on 2021-12-262022-10-31 Journal: Global Medical Genetics [Category] COVID-19, [키워드] adverse event bleeding Causal Coagulopathies commonality COVID-19 cross-reaction cross-reactive cross-reactivity Diseases disorder Epitopes extreme Hemostasis human protein human proteins immune system immunization immunological immunological imprinting Immunological memory Imprinting individual mutated natural infection pathogen pentapeptide peptide response role SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike glycoprotein SARS-CoV-2 spike gp sequence thromboembolic thromboembolic complications thromboses thromboses-related proteins vaccinal Vascular vascular diseases Venous thrombosis [DOI] 10.1055/s-0041-1731068 PMC 바로가기 [Article Type] Original Article
From Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Immune Response to Cancer Onset via Molecular Mimicry and Cross-ReactivityOriginal Article Published on 2021-12-072022-10-31 Journal: Global Medical Genetics [Category] COVID-19, [키워드] acute respiratory syndrome analyzed Antigen Autoimmune Cancer cancer epidemic coronavirus coronavirus 2 cross-reactive cross-reactivity database described Epitopes individual Long COVID material mimicry molecular molecular mimicry objective Onset overlap pandemic pathogen pentapeptide peptide potential mechanism Protein Proteins question respiratory response Result retrieved risk SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike glycoprotein SARS-CoV-2 spike gp Support Surveillance tumor-suppressor proteins tumors UniProt Viral antigen virus [DOI] 10.1055/s-0041-1735590 PMC 바로가기 [Article Type] Original Article
From Anti-SARS-CoV-2 Immune Response to the Cytokine Storm via Molecular MimicryArticle Published on 2021-09-242022-10-27 Journal: Antibodies [Category] COVID-19, [키워드] acute respiratory syndrome analyzed Anti-inflammatory anti-inflammatory activity anti-inflammatory proteins anti-SARS-CoV-2 vaccines Autoimmune characterized coronavirus cross-reaction cross-reactive cross-reactivity Cytokine storm Cytokine storms disorder Endothelial dysfunction epitope ferritinemia highlight Human hyperinflammation immune system immunologic imprinting immunological individual Infection Innate immunity macrophage activation syndrome memory mimicry molecular molecular mimicry Multiorgan occur pathogen pathogenic pentapeptide peptide potential mechanism Protein response responses SARS-CoV-2 SARS-CoV-2 spike gp spike glycoprotein storm Support the cytokine storm the SARS-CoV-2 vaccinal [DOI] 10.3390/antib10040036 PMC 바로가기 [Article Type] Article
Virtual screening of peptides with high affinity for SARS-CoV-2 main proteaseSARS-CoV-2 주요 프로테아제에 대한 높은 친화도를 갖는 펩타이드의 가상 스크리닝Article Published on 2021-06-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Algorithm API applied caused coronavirus COVID-19 COVID-19 treatment death docking docking score drug Drug repurposing Genetic Genetic algorithm high affinity higher affinity identify M pro molecular docking over pandemic pentapeptide peptide peptide-based peptides Proteases redundancy RESTful API. SARS-CoV-2 SARS-CoV-2 main protease screened selected severe acute respiratory syndrome Coronavirus solution treat Treatment Vaccine development Virtual screening [DOI] 10.1016/j.compbiomed.2021.104363 PMC 바로가기 [Article Type] Article
Vaccine design based on 16 epitopes of SARS‐CoV‐2 spike proteinResearch Article Published on 2020-11-012022-11-01 Journal: Journal of medical virology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Amino acid Analysis antigenic biological activity coronavirus Coverage Cytokines database effective epitope Epitopes GPGPG HLA molecule IEDB immunoinformatics immunological in silico induce isolates linker mutated Mutation non‐synonymous mutation nontoxic outbreak pentapeptide peptide polymorphism populations predicted Protein provided recognize Research SARS‐CoV‐2 SARS‐CoV‐2 screened secretion sequence Spike protein suggested T‐cell the spike protein translated Vaccine vaccine candidate [DOI] 10.1002/jmv.26596 PMC 바로가기 [Article Type] Research Article