Selection of vaccine-candidate peptides from Mycobacterium avium subsp. paratuberculosis by in silico prediction, in vitro T-cell line proliferation, and in vivo immunogenicityImmunology Original Research Published on 2024-01-302024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] CD4+ T-cell lines IFN-γ in silico analysis MHC binding prediction Paratuberculosis peptide vaccine test interference [DOI] 10.3389/fimmu.2024.1297955 PMC 바로가기 [Article Type] Immunology Original Research
Harnessing immunoinformatics for developing a multiple-epitope peptide-based vaccination approach against SARS-CoV-2 spike proteinOriginal Article Published on 2023-04-282024-09-05 Journal: Saudi Journal of Biological Sciences [Category] update2024, [키워드] B-epitopes immunoinformatics peptide vaccine SARS-CoV-2 T-epitopes [DOI] 10.1016/j.sjbs.2023.103661 PMC 바로가기 [Article Type] Original Article
A Synthetic SARS-CoV-2-Derived T-Cell and B-Cell Peptide Cocktail Elicits Full Protection against Lethal Omicron BA.1 Infection in H11-K18-hACE2 Micearticle Published on 2023-03-132024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] COVID-19 Omicron variant peptide vaccine SARS-CoV-2 synthetic peptides T-cell epitope [DOI] 10.1128/spectrum.04194-22 PMC 바로가기 [Article Type] article
Recent trends in next generation immunoinformatics harnessed for universal coronavirus vaccine designReview Published on 2023-03-012023-07-09 Journal: Pathogens and global health [Category] COVID19(2023년), [키워드] characterization database Epitope prediction human coronavirus immunoinformatics peptide vaccine vaccine target. [DOI] 10.1080/20477724.2022.2072456 PMC 바로가기 [Article Type] Review
SARS-CoV-2 Vaccines: Types, Working Principle, and Its Impact on Thrombosis and Gastrointestinal DisordersReview Published on 2023-02-012023-07-10 Journal: Applied biochemistry and biotechnology [Category] COVID19(2023년), [키워드] Gastrointestinal disorders nucleic acid vaccine peptide vaccine SARS-CoV-2 thrombosis Viral vector vaccine Virus vaccine. [DOI] 10.1007/s12010-022-04181-3 PMC 바로가기 [Article Type] Review
Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodiesarticle Published on 2023-01-242024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] conserved regions cross-recognizing antibodies Omicron variant peptide vaccine SARS-CoV-2 [DOI] 10.3389/fimmu.2022.1044025 PMC 바로가기 [Article Type] article
Immuno-informatics profiling of monkeypox virus cell surface binding protein for designing a next generation multi-valent peptide-based vaccineArticle Published on 2022-11-022023-06-09 Journal: Frontiers in Immunology [Category] Fulltext, 원숭이두창, [키워드] molecular docking molecular dynamic simulation assay Monkeypox virus next generation multi-valent vaccine peptide vaccine [DOI] 10.3389/fimmu.2022.1035924 PMC 바로가기
The potential of developing a protective peptide-based vaccines against SARS-CoV-2Article Published on 2022-09-012022-11-15 Journal: Drug development research [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antigens approved B-cell cellular COVID-19 COVID-19 vaccine CTL effective Efficacy Genetic genetic material genetic vaccines host cell humoral humoral immune response infectious disease outbreak investigated kill less lineages neutralize Neutralizing antibodies occur opsonize overcome pandemic peptide peptide epitope peptide vaccine Peptide vaccines peptide-based vaccine Protective Protein Reinfection Replication response Safe Safety SARS-CoV-2 SARS-CoV-2-specific antibody Spanish flu T-cell Vaccine Vaccines variant virus [DOI] 10.1002/ddr.21969 PMC 바로가기
Identification of promising CD8 and CD4 T cell epitopes for peptide vaccine formulation against SARS-CoV-2Article Published on 2022-04-052023-07-08 Journal: Archives of Microbiology [Category] COVID19(2023년), [키워드] peptide vaccine SARS-CoV-2 T cell epitopes [DOI] 10.1007/s00203-022-02845-6 PMC 바로가기
A Next-Generation Vaccine Candidate Using Alternative Epitopes to Protect against Wuhan and All Significant Mutant Variants of SARS-CoV-2: An Immunoinformatics ApproachOriginal Article Published on 2021-12-012022-10-28 Journal: Aging and Disease [Category] COVID-19, [키워드] added antigenic epitope applied approach B cell B.1.1.28 B.1.1.7 B.1.351 bioinformatics boost immunity candidate codon optimization computational tools country demonstrated develop epitope expression flexible host immune system identify immunoinformatics In silico cloning Interaction linker molecular molecular docking analysis multi-epitopes mutagenic mutant mutant variants N-terminal next-generation vaccine parameter peptide peptide vaccine peptide-based physicochemical property Region SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants second wave Significant stability T cell epitopes the vaccine Vaccine vaccine candidate vaccine construct variant variants variants of SARS-CoV-2 VoC were assessed were used Wuhan [DOI] 10.14336/AD.2021.0518 PMC 바로가기 [Article Type] Original Article