Natural SARS-CoV-2 Infection in a Free-Ranging Black-Tailed Marmoset (Mico melanurus) from an Urban Area in Mid-West Brazil브라질 중서부 도시 지역의 자유 범위 검은꼬리 마모셋(Mico melanurus)에서 자연적인 SARS-CoV-2 감염Article Published on 2022-06-012022-09-11 Journal: Journal of comparative pathology [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] alveolar septa animal Antigen Area Black-Tailed Marmoset Brazil clinical history COVID-19 female Hepatitis Host human populations immunohistochemistry Interstitial nephritis intestine large intestine liver lung lung tissue Lymph node Lymphocytes lymphoid marmoset Mild motor vehicle nasopharyngeal natural natural infection necropsy New World New World monkey nodule one health oropharyngeal swab pathogen Pathogens peribronchial periportal platyrrhines. Polytrauma pool Protein risk SARS-CoV-2 SARS-COV-2 infection Spike protein spleen state the viral nucleocapsid urban urban area viral nucleocapsid protein Viral RNA viral RNA detection [DOI] 10.1016/j.jcpa.2022.03.005 PMC 바로가기 [Article Type] Article
SARS CoV-2 (Delta Variant) Infection Kinetics and Immunopathogenesis in Domestic CatsSARS CoV-2(Delta Variant) 감염 역학 및 국내 고양이의 면역 병인 발생Article Published on 2022-06-012022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2-expressing cell ACE2-expressing cells acute COVID-19 acute infection animal model animal models B.1.617.2 chemokine chemokine signaling circulating Clinical sign Cluster correlated correlation COVID-19 disease COVID-19 disease course Critical cytokine receptor Delta delta variant develop differentially expressed gene Differentially expressed genes disease Disease progression disease transmission Divergence domestic cats dose downstream dysregulated evaluate feline ferrets flexible genetic modification help highlight Host hub genes identify immunopathology include Infection Infectious virus Inflammatory inflammatory pathways inoculated Interaction interactions intranasally Kinetics lesion lesions limitation lung lung tissue Lungs Mild nasal network analysis non-human primates pathology pathway peribronchial Pneumocytes Post-infection Prevent progression pulmonary inflammation pulmonary lesion pulmonary lesions Respiratory disease RNA sequencing SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants secretion significantly Spread target therapeutic timepoints transgenic mice translational upregulation variant Vascular endothelium Vasculitis Viral antigen Viral protein virus WGCNA wild-type SARS-CoV-2 [DOI] 10.3390/v14061207 PMC 바로가기 [Article Type] Article
Vascular Damage, Thromboinflammation, Plasmablast Activation, T-Cell Dysregulation and Pathological Histiocytic Response in Pulmonary Draining Lymph Nodes of COVID-19COVID-19의 폐 배수 림프절에서 혈관 손상, 혈전 염증, 원형질모세포 활성화, T-세포 조절 장애 및 병리학적 조직구 반응Immunology Published on 2021-12-132022-09-11 Journal: Frontiers in Immunology [Category] SARS, 치료기술, [키워드] accumulation Activation alveolar damage Analysis Autopsy bronchoalveolar lavage sample bronchoalveolar lavage samples CD105 CD36 collected Control COVID-19 COVID-19 case DAD damage demonstrated Depletion Diffuse alveolar damage downregulation Draining draining lymph node dysfunction dysregulated immune response dysregulation EBV enrolled Epstein Barr virus evidence of evidenced expression profiling FIBRIN FLT1 follicular follicular hyperplasia FOXP3 Gene expression profiling germinal centers herpes Herpes virus herpes viruses histology HLH immunohistochemical staining immunological immunopathology incidence infectious mononucleosis initial LEF1 lymph Lymph node lymph nodes Macrophage macrophage activation marker maturation Microarray microthrombi Migration mounted node Panel pathological pathway peribronchial Peripheral blood phenotype plasmablast plasmablasts positive PROCR provided pulmonary Reactivation response responsible Sample SARS-CoV-2 selected severe COVID-19 staining T-cell T-cell dysregulation T-cells TEK Thromboinflammation thrombosis tissue tracheal upregulation viruses vWF was performed widespread [DOI] 10.3389/fimmu.2021.763098 PMC 바로가기 [Article Type] Immunology
Vaccine-Associated Disease Enhancement (VADE): Considerations in Postvaccination COVID-19Case Report Published on 2021-10-292022-10-31 Journal: Case Reports in Medicine [Category] COVID-19, [키워드] accelerated Affect Asymptomatic COVID-19 Clinicians CoronaVac Course COVID-19 COVID-19 pandemic disease dose enhancement hospital illustration immunization incidence individual induce Infection infiltration inflammatory process manifestation neutralizing antibody Neutralizing antibody titer observation Occurrence Patient peribronchial Pneumonia produced proinflammatory pulmonary symptom Respiratory disease Symptom the disease understanding vaccinated individual vaccination Vaccination strategy Vaccine [DOI] 10.1155/2021/9673453 PMC 바로가기 [Article Type] Case Report
Vaping, SARS-CoV-2, and Multisystem Inflammatory Syndrome: A Perfect StormPediatrics Published on 2021-05-122022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] ACE ACE2 ACE2 receptors acute respiratory distress alteration ARDS association characterized children clearance consequence COVID-19 Defense develop disease Electronic cigarette EVALI fibrosis Health highlight immune system Impact Inflammation Inflammatory MIS-C morbidities Multisystem inflammatory syndrome oxidative stress pandemic peribronchial plethora Protective receptor respiratory symptom resulting risk SARS-CoV-2 shown storm syndrome target unique upregulation vaping vaping-associated lung injury virus [DOI] 10.3389/fped.2021.647925 PMC 바로가기 [Article Type] Pediatrics