peripheral – Communicable Diseases Research

The Peripheral Immune Landscape in a Patient with Myocarditis after the Administration of BNT162b2 mRNA Vaccine

Article

Published on 2022-10-312022-11-15
Journal: Molecules and cells [Category] COVID19(2023년), SARS, 진단, 치료기술,

Reconstructed Genome-Scale Metabolic Model Characterizes Adaptive Metabolic Flux Changes in Peripheral Blood Mononuclear Cells in Severe COVID-19 Patients

Article

Published on 2022-10-172022-11-15
Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료제,

[키워드] acute respiratory syndrome adaptive aerobic Analysis anti-inflammatory effect antiviral drugs biogenesis caused change changes in Coronavirus disease 2019 Coronavirus-2 COVID-19 differentially expressed enzyme FASN fatty flux Glycolysis Health Immune cell Inflammation Inflammatory lipids mechanism metabolic metabolic model metabolism metabolism-directed therapy. metabolites Model mononuclear cell nucleotide oxidative phosphorylation pathogenic PBMC PBMCs peripheral Peripheral blood potential therapeutic targets provide reaction reconstructed Regulation responsible retinol SARS-CoV-2 severe COVID-19 patients SLC2A3 therapy Transcriptome Treatment Vitamin
[DOI] 10.3390/ijms232012400 PMC 바로가기

COVID-19 and Peripheral Artery Thrombosis: A Mini Review

Review article

Published on 2022-10-012022-10-05
Journal: Current problems in cardiology [Category] COVID19(2023년), SARS, 변종, 진단,

Neuroinflammation in Dementia-Therapeutic Directions in a COVID-19 Pandemic Setting

Article

Published on 2022-09-222022-11-15
Journal: Cells [Category] SARS, 진단,

Immune response to SARS-CoV-2 vaccination in relation to peripheral immune cell profiles among patients with multiple sclerosis receiving ocrelizumab

오크렐리주맙을 투여받는 다발성 경화증 환자의 말초 면역 세포 프로필과 관련된 SARS-CoV-2 백신 접종에 대한 면역 반응

Article

Published on 2022-09-012022-09-12
Journal: Journal of neurology, neurosurgery, and psychiatry [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] adverse event analysed antibodies antibody B cell B cell subset baseline Blood Cell-mediated immunity Clinical data Clinical effect clinical trial correlated courses effective facilitate Follow-up humoral immune response identify IFN-γ IgM Immune cell immune response Immunocompromised patient Immunomodulatory therapies interferon long-lasting median multiple sclerosis parameter Patient patients performed peripheral peripheral lymphocyte Plasma cell positive correlation positively correlated preserved profile receiving required Retrospective study SARS-CoV-2 transmission SARS-CoV-2 vaccination SARS-CoV-2 vaccine severe disease T cell response titre titres treatment regimen vaccinate vaccination vaccine dose were assessed were measured
[DOI] 10.1136/jnnp-2021-328197 PMC 바로가기 [Article Type] Article

Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination

Article

Published on 2022-08-292022-11-16
Journal: Medical science monitor : international medical jo [Category] 유전자 메커니즘,

[키워드] Analysis ASB16 biological process Cell Characteristics Cluster conducted core gene COVID-19 COVID-19 pandemic DEGs detect differentially expressed gene enrichment evaluate expressed facilitate FBXO11 FOXA1 FOXC1 functional GATA2 Gene expression analysis Genes healthy controls hsa-miR-1-3p identify Interaction ITCH macrophages miRNA molecular mononuclear cell Patient performed peripheral Peripheral blood platform progression protein ubiquitination protein-protein interaction regulate Regulating Regulatory response RNA sequencing RNF130 severe COVID-19 signaling pathways single-cell transcription factors Transcriptome TRIM21 UBE2J1 was used were expressed YY1
[DOI] 10.12659/MSM.937532 PMC 바로가기

Specific CD4+ T Cell Responses to Ancestral SARS-CoV-2 in Children Increase With Age and Show Cross-Reactivity to Beta Variant

어린이의 조상 SARS-CoV-2에 대한 특정 CD4+ T 세포 반응은 나이가 들어감에 따라 증가하고 베타 변이체에 대한 교차 반응성을 나타냅니다

Article

Published on 2022-07-152022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] accompanied Activation activation induced marker (AIM) activation-induced marker activation-induced markers age ancestral Antiviral average Beta Beta variant beta variants Blood CD4+ CD4+ T cell children Control convalescent coronavirus COVID-19 cross-reactivity Cytokines cytometric disease course Effective vaccines Flow global health granzyme granzyme B HCoV Health human coronavirus human coronavirus (HCoV) IFN-γ immune response increase Infection infection rate infection rates marker Mild mononuclear cell PBMC pediatric peptide peripheral Peripheral blood Peripheral blood mononuclear cells reduced reduction response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant secreted cytokine secretion seronegative show social distancing measures Specific stimulated T cell T cell responses T cells the SARS-CoV-2 vaccination variant variant of concern (VOC) viral variant VoC was reduced were used
[DOI] 10.3389/fimmu.2022.867577 PMC 바로가기 [Article Type] Article

Immune Cells Profiles In The Peripheral Blood Of Patients With Moderate To Severe COVID-19 And Healthy Subjects With and Without Vaccination With The Pfizer-BioNTech mRNA Vaccine

Pfizer-BioNTech mRNA 백신 접종 여부에 관계없이 중등도에서 중증 COVID-19 환자 및 건강한 피험자의 말초혈 면역 세포 프로필

Article

Published on 2022-07-112022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술,

[키워드] acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptive analyzed B cell B cells Blood causative agent caused CD14 CD16 CD19 CD19+ CD3+ CD4+ CD4+ T cells CD4+ T lymphocyte CD56 CD56+ CD8+ T cell CD8+ T cells clinical manifestations coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients detectable determine dysregulated flow cytometry Frequency group healthy control healthy subject healthy subjects HLA-DR host response immune Immune cell immune cells immune response Inflammatory Kuwait lymphocyte Lymphocyte subset Lymphocyte subsets Lymphocytes moderate moderate to severe monocyte monocyte subsets Monocytes mRNA mRNA vaccine NK cell NK cells no symptom no symptoms percentage percentages peripheral Peripheral blood Perturbation perturbations Pfizer Pfizer-BioNTech profile profiles PROTECT required respiratory SARS-CoV-2 Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe disease significantly higher significantly lower subjects subset T cells T lymphocytes the patient three group three groups vaccination was performed with COVID-19
[DOI] 10.3389/fimmu.2022.851765 PMC 바로가기 [Article Type] Article

A Path-Based Analysis of Infected Cell Line and COVID-19 Patient Transcriptome Reveals Novel Potential Targets and Drugs Against SARS-CoV-2

감염된 세포주 및 COVID-19 환자 전사체의 경로 기반 분석을 통해 SARS-CoV-2에 대한 새로운 잠재적 표적 및 약물 공개

Article

Published on 2022-07-012022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] ADCY2 ADSL Against anti-SARS-CoV-2 ATP bemcentinib biological network BUB1 Cell cell line cell lines central gene central genes changes Concordance conivaptan COVID-19 COVID-19 severity curated DEGs DEGs (Differentially Expressed Genes) Differentially expressed genes drug drugs targeting dysregulated e genes G1/S transition Genes greater identify Infection leukocyte leukocyte activation LINE metabolic process Migration MOST network analysis novel OCRL PBK PBMC PBMCs PBMCs (Peripheral Blood Mononuclear Cells) peripheral Peripheral blood Peripheral blood mononuclear cells phthalocyanine Potential reveal SARS-C0V-2 SARS-CoV-2 SARS-COV-2 infection severity target target gene TIAM1 Transcriptome transcriptomic viruses with COVID-19
[DOI] 10.3389/fimmu.2022.918817 PMC 바로가기 [Article Type] Article

Peripheral lymphocyte subset counts predict antibody response after SARS-CoV-2 mRNA-BNT162b2 vaccine in cancer patients: Results from the Vax-On-Profile study

말초 림프구 하위 집합 수는 암 환자에서 SARS-CoV-2 mRNA-BNT162b2 백신 후 항체 반응을 예측합니다: Vax-On-Profile 연구 결과

Article

Published on 2022-07-012022-09-11
Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] Adaptive immune response Analysis anti-RBD Antibody Response Antibody titer Antibody titers B cell B cells Cancer cancer patient Cancer patients Chemotherapy circulating collected correlation Corticosteroid corticosteroid therapy COVID-19 COVID-19 vaccination Cytotoxic chemotherapy defined Flow cytometry analysis helper cell humoral humoral immunogenicity Humoral response IgG IgG antibodies IgG antibody IgG titer immunosuppressive indicated interactions linear correlation lymphocyte Lymphocyte subset Lymphocyte subsets mRNA Multivariate analysis Negative predictive value Occurrence Patient peripheral Peripheral blood positive positive linear correlation predict Predictive Predictive value Protein Quantitative RBD receiving Receptor-binding domain Result ROC Curve SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccine seroconversion rate seroconversion rates seroconversion response serologic testing Serologically shown significantly spike Spike protein subgroups subpopulations subset symptomatic infections T helper T helper cell T helper cell. tested the receptor-binding domain the SARS-CoV-2 treated Univariate analysis vaccination efficacy Vaccine
[DOI] 10.1016/j.intimp.2022.108774 PMC 바로가기 [Article Type] Article