Leprosy case series in the emergency room: A warning sign for a challenging diagnosisarticle Published on 2021-10-312024-09-01 Journal: The Brazilian Journal of Infectious Diseases [Category] 한센병, [키워드] emergency medicine leprosy Neuritis peripheral nerves [Article Type] article
Bioinformatic analyses hinted at augmented T helper 17 cell differentiation and cytokine response as the central mechanism of COVID‐19–associated Guillain‐Barré syndrome생물정보학 분석은 COVID-19 관련 길랑-바레 증후군의 중심 기전으로서 증강된 T 헬퍼 17 세포 분화 및 사이토카인 반응을 암시Original Article Published on 2021-03-102022-09-10 Journal: Cell Proliferation [Category] SARS, 유전자 메커니즘, [키워드] Abnormalities Activation Algorithm Analysis analyzed association autoimmune attack autonomic Bioinformatic CD86 cell differentiation Cluster Clustering conditions COVID‐19 COVID‐19 CSF2 cytokine cytokine response databases demonstrated disease disease entity DisGeNET Evidence Genes Genetic Guillain‐Barré syndrome IL10 IL1B IL23A IL27 IL2RA IL4 IL6 Interaction ISG20 ITGAM knowledge Macrophage Markov material mechanism mononuclear cell mononuclear cells network analysis objective parameter pathophysiological mechanism pathway Patient PBMC performed Peripheral blood Peripheral blood mononuclear cells peripheral nerves platform PTGS2 Regulatory regulatory genes required Result retrieved risk SARS‐CoV‐2 shown STRING subset suggested syndrome T helper Th17 TNF Transcriptome transcriptome analysis Version was used [DOI] 10.1111/cpr.13024 PMC 바로가기 [Article Type] Original Article
SARS-CoV-2 Dissemination Through Peripheral Nerves Explains Multiple Organ InjuryNeuroscience Published on 2020-08-052022-10-31 Journal: Frontiers in Cellular Neuroscience [Category] COVID-19, [키워드] acute respiratory distress Asymptomatic axonal transport Blood blood vessels Brain caused characterized Clinical presentations clinically coronavirus Coronaviruses Course detectable develop diffusion disease disseminate distress exaggerated immune response eyes infect infected cells infected individual Infection Injury intestines Invasion kidneys less liver Lung pathology Lungs macrophages membrane mild respiratory symptoms mucosa Multiple multiple organ failure nerve nerve terminal Neurological involvement Neurological symptom Neurological symptoms neurotropic infection olfactory neuroepithelium organ organ injury Patient patients peripheral peripheral nerves question raising recovered patients reported Research respiratory infection SARS-CoV-2 Severe case severe pneumonia severely ill patient subcellular syndrome T lymphocytes the disease Transport virus virus spread while [DOI] 10.3389/fncel.2020.00229 PMC 바로가기 [Article Type] Neuroscience
Pathological, ultrasonographic, and electrophysiological characterization of clinically diagnosed cases of pure neuritic leprosyarticle Published on 2020-06-302024-09-01 Journal: Journal of the Peripheral Nervous System [Category] 한센병, [키워드] leprosy Mycobacterium leprae Nerve Thickening peripheral nerves Polyneuropathy pure neuritic leprosy [Article Type] article
Mapping of PARK2 and PACRG Overlapping Regulatory Region Reveals LD Structure and Functional Variants in Association with Leprosy in Unrelated Indian Population GroupsPARK2 및 PACRG 겹치는 규제 영역의 매핑은 관련 없는 인도 인구 그룹의 나병과 관련된 LD 구조 및 기능적 변이를 나타냅니다.Research Article Published on 2013-07-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 한센병, [키워드] a major Affect assay association Author caused China clinical forms compared declined different disease disease pathogenesis Frequency Gene Gene Expression genetic background Genome genomic region granulomatous infection groups health problem heterogeneity Host human gene human genes impairment India Infection Infectious disease leprosy mapping Mycobacterium Mycobacterium leprae North organism other variant other variants PACRG Pathogenesis peripheral nerves Population population group population groups populations Prevalence provide public health reason for Region regulatory region replicated Replication reported reporter saturated several gene several genes significantly skin SNP SNPs Structure structures susceptibility the disease therapy upstream [DOI] 10.1371/journal.pgen.1003578 PMC 바로가기 [Article Type] Research Article