Antimalarials Targeting the Malaria Parasite Cation ATPase P. falciparum ATP4 (PfATP4)article Published on 2023-12-312024-09-01 Journal: Current Topics in Medicinal Chemistry [Category] 말라리아, [키워드] Antimalarial drugs Clinical and pre-clinical development drug resistance malaria Malaria clinical trials parasite plasma membrane PfATP4 Plasmodium falciparum [Article Type] article
Pf ATP4 inhibitors in the Medicines for Malaria Venture Malaria Box and Pathogen Box block the schizont-to-ring transition by inhibiting egress rather than invasionarticle Published on 2022-11-302024-09-01 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] egress Invasion malaria malaria box Pathogen Box PfATP4 Plasmodium falciparum sodium ions [Article Type] article
Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum IsolatesArticle Published on 2021-09-172024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] Cipargamin drug resistance KAE609 malaria PA92 PfATP4 Plasmodium falciparum SJ733 Uganda
Indole: The After Next Scaffold of Antiplasmodial Agents?article Published on 2020-11-302024-09-01 Journal: Drug Design, Development and Therapy [Category] 말라리아, [키워드] antimalarial agents hemozoin inhibition indole multi-target approach PfATP4 [Article Type] article
Biochemical characterization and chemical inhibition of PfATP4-associated Na+-ATPase activity in Plasmodium falciparum membranesArticle Published on 2018-08-242024-08-28 Journal: Brain stimulation [Category] 말라리아, [키워드] antiplasmodial drug ATPase Cipargamin drug action drug resistance malaria membrane transport PfATP4 Plasmodium falciparum sodium transporter.
Cell Swelling Induced by the Antimalarial KAE609 (Cipargamin) and Other PfATP4-Associated AntimalarialsArticle Published on 2018-05-252024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] antimalarial agents KAE609 PfATP4 transporters.
Spiroindolone NITD609 is a novel antimalarial drug that targets the P-type ATPase PfATP4article Published on 2016-12-312024-09-01 Journal: Future Med Chem [Category] 말라리아, [키워드] Cipargamin KAE609 malaria NIDT609 PfATP4 Plasmodium Spiroindolone [Article Type] article
The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugsArticle Published on 2015-08-272024-08-29 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] antimalarial Cipargamin Drug discovery PfATP4 Plasmodium Resistance selection.
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of PlasmodiumArticle Published on 2014-12-162024-08-29 Journal: Microbial Cell Factories [Category] 말라리아, [키워드] Drug discovery malaria PfATP4