Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiologyArticle Published on 2024-01-162024-08-29 Journal: mBio [Category] 말라리아, [키워드] drug resistance evolution fitness malaria Pfcrt Plasmodium falciparum
Epitope specific antibodies to N- and C cytoplasmic domains of the Plasmodium falciparum chloroquine resistance transporter (PfCRT) differentiate native and post-translationally modified variantarticle Published on 2023-08-312024-09-01 Journal: Biochemical and Biophysical Research Communications [Category] 말라리아, [키워드] epitope mapping malaria Pfcrt Phosphorylation-specific antibody Plasmodium falciparum [Article Type] article
Current status of 4-aminoquinoline resistance markers 18 years after cessation of chloroquine use for the treatment of uncomplicated falciparum malaria in the littoral coastline region of Cameroonarticle Published on 2022-12-312024-09-01 Journal: Pathogens and Global Health [Category] 말라리아, [키워드] 4-aminoquinoline alleles buea drug resistance Pfcrt Pfmdr1 Plasmodium falciparum [Article Type] article
Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfcrt and pfmdr1 genes in isolates from Honduras and Nicaragua, 2018–2021온두라스와 니카라과에서 2018-2021년 동안 분리된 Plasmodium falciparum 항말라리아 약물 저항성 마커의 pfcrt 및 pfmdr1 유전자 평가Research Published on 2021-12-142024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] drug resistance honduras Nicaragua Pfcrt Pfmdr1 Plasmodium falciparum Surveillance [DOI] 10.1186/s12936-021-03977-8 PMC 바로가기 [Article Type] Research
Mutations in Pfcrt and Pfmdr1 genes of Plasmodium falciparum isolates from two sites in Northcentral and Southwest Nigeriaarticle Published on 2021-11-302024-09-01 Journal: Infection, Genetics and Evolution [Category] 말라리아, [키워드] mutations Nigeria Northcentral Pfcrt Pfmdr1 Plasmodium falciparum Southwest [Article Type] article
The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan region, southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt genearticle Published on 2021-11-302024-09-01 Journal: Parasitology Research [Category] 말라리아, [키워드] Chloroquine drug resistance Infectious diseases malaria Pfcrt Plasmodium falciparum Saudi Arabia [Article Type] article
Pyronaridine-Artesunate (Pyramax) for Treatment of Artemisinin- and Piperaquine-Resistant Plasmodium falciparum in the Central Highlands of VietnamArticle Published on 2021-11-172024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] antimalarial drug resistance Central Highlands dihydroartemisinin exo-E415G Pfcrt pfkelch13 Pfmdr1 Piperaquine plasmepsin 2/3 Plasmodium falciparum Pyramax pyronaridine Pyronaridine-artesunate Vietnam
SELECTION OF PFCRT 76T AND PFMDR1 86Y MUTANT PLASMODIUM FALCIPARUM AFTER TREATMENT OF UNCOMPLICATED MALARIA WITH ARTESUNATE-AMODIAQUINE IN REPUBLIC OF GUINEAArticle Published on 2021-09-012024-08-28 Journal: J Parasitol [Category] 말라리아, [키워드] drug resistance Guinea malaria Pfcrt Pfmdr1 Plasmodium falciparum
Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlookarticle Published on 2021-08-312024-09-01 Journal: International Journal for Parasitology: Drugs and Drug Resistance [Category] 말라리아, [키워드] Artemisinin drug resistance hemoglobin digestion K13 molecular surveillance Pfcrt Pfmdr1 Piperaquine Plasmodium falciparum stress response [Article Type] article
Selection of pfcrt K76 and pfmdr1 N86 Coding Alleles after Uncomplicated Malaria Treatment by Artemether-Lumefantrine in Mali말리에서 아르테메터-루메판트린으로 간단한 말라리아 치료 후 pfcrt K76 및 pfmdr1 N86 코딩 대립유전자 선택Article Published on 2021-06-032024-08-08 Journal: International Journal of Molecular Sciences [Category] 말라리아, [키워드] artemether-lumefantrine Mali Pfcrt Pfmdr1 Plasmodium falciparum [DOI] 10.3390/ijms22116057 PMC 바로가기 [Article Type] Article