Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activitiesarticle Published on 2024-03-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] P. falciparum PfDHODH Pyrazolopyrimidine quinoline Transmission blockers triazolopyrimidine [Article Type] article
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitorsarticle Published on 2021-01-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] malaria P. falciparum PfDHODH Pyrazolopyrimidine quinoline triazolopyrimidine [Article Type] article
Plasmodium falciparum dihydroorotate dehydrogenase: a drug target against malariaArticle Published on 2018-08-012024-08-28 Journal: Future Med Chem [Category] 말라리아, [키워드] antimalarial dihydroorotate dehydrogenase malaria PfDHODH Plasmodium falciparum