Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoesArticle Published on 2023-02-142024-08-27 Journal: Immunity [Category] 말라리아, [키워드] Crystallography human monoclonal antibodies malaria Pfs48/45 Plasmodium falciparum transmission-blocking vaccine transmission-reducing activity.
Structural vaccinology of malaria transmission-blocking vaccinesarticle Published on 2021-02-282024-09-01 Journal: Expert review of vaccines [Category] 말라리아, [키워드] fertilization Gamete gametocyte malaria monoclonal antibodies Ookinete pfhap2 Pfs230 Pfs25 Pfs47 Pfs48/45 Plasmodium falciparum Standard membrane feeding assay structural vaccinology Transmission blocking vaccine Vaccine design Zygote [Article Type] article
A Reproducible and Scalable Process for Manufacturing a Pfs48/45 Based Plasmodium falciparum Transmission-Blocking VaccinePfs48/45 기반 말라리아 감염 차단 백신 제조를 위한 재현 가능하고 확장 가능한 프로세스Original Research Published on 2021-01-112024-08-11 Journal: Frontiers in immunology [Category] 말라리아, [키워드] current Good Manufacturing Practices Lactococcus lactis malaria Pfs48/45 R0.6C transmission-blocking Vaccine [DOI] 10.3389/fimmu.2020.606266 PMC 바로가기 [Article Type] Original Research
Immune Responses to Gametocyte Antigens in a Malaria Endemic Population—The African falciparum Context: A Systematic Review and Meta-Analysis말라리아 풍토병 인구에서 생식세포 항원에 대한 면역 반응—아프리카 파르바룸 맥락: 체계적 검토 및 메타 분석Article Published on 2019-10-222024-08-11 Journal: Frontiers in immunology [Category] 말라리아, [키워드] Gametocytes Immunity Pfs230 Pfs48/45 Plasmodium falciparum [DOI] 10.3389/fimmu.2019.02480 PMC 바로가기
Expression of full-length Plasmodium falciparum P48/45 in P. berghei blood stages: A method to express and evaluate vaccine antigensarticle Published on 2018-09-302024-09-01 Journal: Molecular and Biochemical Parasitology [Category] 말라리아, [키워드] immunization Pfs48/45 Plasmodium Standard membrane feeding Transgene-expression transmission blocking [Article Type] article
Antibody responses to two new Lactococcus lactis -produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of Ghana말라리아 환자가 가나 중앙 지역에 거주할 때, 두 가지 새로운 Lactococcus lactis에서 생산된 재조합 Pfs48/45 및 Pfs230 단백질에 대한 항체 반응은 나이에 따라 증가합니다.Research Published on 2017-08-012024-08-12 Journal: Malaria Journal [Category] 말라리아, [키워드] Lactococcus lactis malaria Pfs230 Pfs48/45 seropositive transmission-blocking [DOI] 10.1186/s12936-017-1955-0 PMC 바로가기 [Article Type] Research
Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like displayArticle Published on 2017-06-272024-08-27 Journal: Vaccine [Category] 말라리아, [키워드] Acinetobacter phage AP205, virus-like-particles Pfs48/45 Plasmodium falciparum SMFA transmission-blocking [DOI] 10.1016/j.vaccine.2017.05.054
Towards clinical development of a Pfs48/45-based transmission blocking malaria vaccinearticle Published on 2017-04-302024-09-01 Journal: Expert review of vaccines [Category] 말라리아, [키워드] Gametocytes malaria Pfs48/45 Plasmodium falciparum Subunit vaccine Transmission blocking vaccine (TBV) [Article Type] article
Reduced immunogenicity of Plasmodium falciparum gamete surface antigen (Pfs48/45) in mice after disruption of disulphide bonds – evaluating effect of interferon-γ-inducible lysosomal thiol reductasearticle Published on 2016-08-312024-09-01 Journal: Immunology [Category] 말라리아, [키워드] antigen processing antigen structure interferon-γ-inducible lysosomal thiol reductase malaria Pfs48/45 Vaccine [Article Type] article
Synthetic TLR4 agonists enhance functional antibodies and CD4+ T-cell responses against the Plasmodium falciparum GMZ2.6C multi-stage vaccine antigenArticle Published on 2016-04-272024-08-27 Journal: Vaccine [Category] 말라리아, [키워드] CD4 T-helper cells GLA GMZ2 Pfs48/45 Plasmodium falciparum SLA transmission blocking [DOI] 10.1016/j.vaccine.2016.03.016