Assessing pH-Dependent Conformational Changes in the Fusion Peptide Proximal Region of the SARS-CoV-2 Spike GlycoproteinArticle Published on 2024-07-022024-09-05 Journal: Viruses [Category] update2024, [키워드] coronavirus membrane fusion pH spike viral entry [DOI] 10.3390/v16071066 PMC 바로가기 [Article Type] Article
Effects of Raman Labeling Compounds on the Stability and Surface-Enhanced Raman Spectroscopy Performance of Ag Nanoparticle-Embedded Silica Nanoparticles as Tagging MaterialsArticle Published on 2024-05-262024-09-05 Journal: Biosensors [Category] update2024, [키워드] Ag NPs Period pH Raman labeling compound SERS tags stability Surface-enhanced Raman spectroscopy temperature [DOI] 10.3390/bios14060272 PMC 바로가기 [Article Type] Article
Comparison of Salivary Secretion, pH, and Buffer Capacity Between COVID-19 Vaccinated and Unvaccinated Child Patients Visiting Dental Clinics of University Hospitals in Riyadh City, Saudi ArabiaOriginal Research Published on 2023-12-252024-09-05 Journal: International Journal of General Medicine [Category] update2024, [키워드] buffer COVID-19 patients pediatric pH salivary secretion Vaccine [DOI] 10.2147/IJGM.S437563 PMC 바로가기 [Article Type] Original Research
Total Antioxidant Capacity of Saliva and Its Correlation with pH Levels among Dental Students under Different Stressful ConditionsArticle Published on 2023-12-122024-09-05 Journal: Diagnostics [Category] update2024, [키워드] pH Saliva STAI test stressful condition total antioxidant capacity [DOI] 10.3390/diagnostics13243648 PMC 바로가기 [Article Type] Article
Virucidal Activities of Acidic Electrolyzed Water Solutions with Different pH Values against Multiple Strains of SARS-CoV-2Article Published on 2023-01-312023-07-11 Journal: Applied and Environmental Microbiology [Category] COVID19(2023년), [키워드] acidic electrolyzed water disinfectant pH SARS-CoV-2 variant strain [DOI] 10.1128/aem.01699-22 PMC 바로가기
The pH Robustness of Bacterial SensingArticle Published on 2022-10-262022-11-16 Journal: mBio [Category] 유전자 메커니즘, [키워드] analyzed appear Bacteria Bacterial bacterial adaptation binding can be used change chaperone chemoreceptor chemotaxis condition conditions COVID-19 pandemic cytosolic demonstrated demonstration determine dimeric domain eight energy Escherichia coli extreme facilitate form Hormones in vivo include information intrinsic isothermal titration calorimetry Ligand ligands mechanism MONITOR Neurotransmitters nine pathway periplasmic pH pH robustness pH value progression Protein Proteins Pseudomonas aeruginosa quorum-sensing receptors recognize reported Research resonance respond response reveal robustness sensing sensor domains signal Signal transduction Signaling TAR tested ultracentrifugation was obtained [DOI] 10.1128/mbio.01650-22 PMC 바로가기
Unveiling the Effect of Low pH on the SARS-CoV-2 Main Protease by Molecular Dynamics SimulationsArticle Published on 2021-11-052022-10-28 Journal: The British journal of oral & maxillofacial surger [Category] COVID-19, [키워드] acidic pH Affect analysed catalytic change changes conditions coronavirus Cys145 distribution docking docking analysis Dynamics Effect evaluated His41 inhibitor Interaction mechanism molecular dynamics MPro not affected PF-00835231 Pfizer pH Replication residue SARS-CoV-2 Mpro Simulation solvent stability the SARS-CoV-2 therapeutic target Transcription Volume was performed [DOI] 10.3390/polym13213823 PMC 바로가기 [Article Type] Article
The Role of Acidosis in the Pathogenesis of Severe Forms of COVID-19Review Published on 2021-08-312022-10-28 Journal: Biology [Category] COVID-19, [키워드] “cytokine storm” acidosis Anti-inflammatory approach Blood Blood pH Bohr effect Characteristics Clinical outcome conformational change consequence contribute Covid patients COVID-19 COVID-19 patients decrease Deterioration disease dysregulation early stage Effect effort form Gas exchange highlight homeostasis hypoxia immune system infections Inflammation involved Lactate lactic acid less lung mechanism oxygen saturation Pathogenesis pH positive protective antibodies Reactions resulting role S-protein SARS-CoV-2 saturation severe COVID-19 shown simple the disease therapy threshold value thrombosis tissues vicious cycle virus [DOI] 10.3390/biology10090852 PMC 바로가기 [Article Type] Review
Acid pH Increases SARS-CoV-2 Infection and the Risk of Death by COVID-19Medicine Published on 2021-08-202022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 ACE2 expression acid acute respiratory syndrome angiotensin-converting enzyme 2 Barrett's esophagus cell stress Cohort Comorbidities Comorbidity condition coronavirus COVID-19 COVID-19 patient COVID-19 severity death drugs elevated expression Glucose higher risk host receptor Human human tissue hypoxia increase increase in independent individual infect inhibitor lung monocyte Patient pH Proton Pump Inhibitors reduced SARS-CoV-2 SARS-COV-2 infection severe COVID-19 tissue Viral load [DOI] 10.3389/fmed.2021.637885 PMC 바로가기 [Article Type] Medicine
In vitro Dissolution Profile at Different Biological pH Conditions of Hydroxychloroquine Sulfate Tablets Is Available for the Treatment of COVID-19Molecular Biosciences Published on 2021-01-142022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] absorbance Acetate Agilent antimalarial applied Autoimmune diseases Biological buffer Concentration condition coronavirus Coronavirus disease 2019 COVID-19 DAD detection dissolution evaluate experiments globe harmonization HCl HCQ Hydroxychloroquine hydroxychloroquine sulfate ICH in vitro injection International Conference linear methanol parameter pH phosphate buffer Precision profile purified R 2 rheumatoid arthritis specificity Standard deviation sulfate sulfonic acid tablets Treatment validation Volume [DOI] 10.3389/fmolb.2020.613393 PMC 바로가기 [Article Type] Molecular Biosciences