Quantitative analysis of favipiravir and hydroxychloroquine as FDA-approved drugs for treatment of COVID-19 using synchronous spectrofluorimetry: application to pharmaceutical formulations and biological fluids동시 분광형광법을 사용한 COVID-19 치료를 위한 FDA 승인 약물인 favipiravir 및 hydroxychloroquine의 정량 분석: 제약 제제 및 생물학적 유체에 적용Article Published on 2022-06-012022-09-11 Journal: Luminescence : the journal of biological and chemi [Category] COVID19(2023년), SARS, 치료기술, [키워드] Acetate acute respiratory syndrome Analysis applied approach biological fluid biological fluids buffer cause caused condition contagious coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 country COVID-19 Detection limit diluent drug Drug administration Ethanol exhibited Favipiravir FDA-approved drug fluorescence intensity food harmonization Healthcare systems human plasma sample human plasma samples Hydroxychloroquine identify information Interference International Conference investigated limit limits medications Pharmaceutical Preparation pharmaceutical preparations quantitation SARS-CoV-2 sensitivity Severe acute respiratory syndrome synchronous synchronous fluorimetry. Treatment United State United States United States Food and Drug Administration viral infection were measured [DOI] 10.1002/bio.4240 PMC 바로가기 [Article Type] Article
Potential anti-COVID-19 agents, cepharanthine and nelfinavir, and their usage for combination treatmentArticle Published on 2021-03-262022-10-04 Journal: iScience [Category] 비임상, 치료제, [키워드] acute respiratory syndrome anti-inflammatory drug Anti-SARS-CoV-2 Activity Antiviral antiviral activity approved drug binding calculated Cell culture combination treatment combined treatment coronavirus coronavirus disease dose drug candidate drug concentration Efficacy Human immunodeficiency virus inhibit inhibited limit lung Medical Substance nelfinavir pharmaceutical Pharmaceutical Preparation Potential predict predicted proliferation protease inhibition Protease inhibitor Remdesivir required SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 replication screened suppressed synergistic target cell target cells Treatment viral clearance viral replication Virology [DOI] 10.1016/j.isci.2021.102367 PMC 바로가기 [Article Type] Article