SARS-CoV-2 Vaccination Responses in Anti-CD20-Treated Progressive Multiple Sclerosis Patients Show Immunosenescence in Antigen-Specific B and T CellsArticle Published on 2024-08-172024-09-05 Journal: Vaccines [Category] update2024, [키워드] Biomarkers flow cytometry immune response immunosenescence multiple sclerosis Phenotyping Vaccines [DOI] 10.3390/vaccines12080924 PMC 바로가기 [Article Type] Article
Delineation of chicken immune markers in the era of omics and multicolor flow cytometryVeterinary Science Review Published on 2024-05-232024-09-05 Journal: Frontiers in Veterinary Science [Category] update2024, [키워드] chicken flow cytometry leukocytes lineages Phenotyping single-cell biology [DOI] 10.3389/fvets.2024.1385400 PMC 바로가기 [Article Type] Veterinary Science Review
No Remdesivir Resistance Observed in the Phase 3 Severe and Moderate COVID-19 SIMPLE TrialsArticle Published on 2024-03-312024-09-05 Journal: Viruses [Category] update2024, [키워드] genotyping Nsp12 Phenotyping Remdesivir resistance SARS-CoV-2 [DOI] 10.3390/v16040546 PMC 바로가기 [Article Type] Article
Digital analysis of the prostate tumor microenvironment with high-order chromogenic multiplexingOriginal Research Article Published on 2023-11-212024-09-05 Journal: Journal of Pathology Informatics [Category] update2024, [키워드] artificial intelligence Cancer imaging immunofluorescence immunohistochemistry Immunotherapy Phenotyping Spectroscopy Tumor immune microenvironment UMAP [DOI] 10.1016/j.jpi.2023.100352 PMC 바로가기 [Article Type] Original Research Article
Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVIDArticle Published on 2023-10-262024-09-05 Journal: Cell Reports Medicine [Category] update2024, [키워드] Biomarkers COVID-19 Long COVID machine learning metabolomics outcomes Phenotyping post-acute sequelae of COVID-19 proteomics SARS-CoV-2 [DOI] 10.1016/j.xcrm.2023.101254 PMC 바로가기 [Article Type] Article
Evaluating construct validity of computable acute respiratory distress syndrome definitions in adults hospitalized with COVID-19: an electronic health records based approacharticle Published on 2023-08-092024-09-05 Journal: BMC Pulmonary Medicine [Category] update2024, [키워드] acute respiratory distress syndrome construct validity Coronavirus disease 2019 Electronic health records Phenotyping [DOI] 10.1186/s12890-023-02560-y PMC 바로가기 [Article Type] article
Characterizing subgroup performance of probabilistic phenotype algorithms within older adults: a case study for dementia, mild cognitive impairment, and Alzheimer’s and Parkinson’s diseasesResearch and Applications Published on 2023-07-282024-09-05 Journal: JAMIA Open [Category] update2024, [키워드] machine learning Phenotyping subgroup performance [DOI] 10.1093/jamiaopen/ooad043 PMC 바로가기 [Article Type] Research and Applications
Optical diffraction tomography and image reconstruction to measure host cell alterations caused by divergent Plasmodium speciesarticle Published on 2023-02-282024-09-01 Journal: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy [Category] 말라리아, [키워드] 3D-imaging Hemozoin malaria Optical diffraction tomography Phenotyping red blood cells [Article Type] article
Reactogenicity and immunogenicity of the second COVID-19 vaccination in patients with inborn errors of immunity or mannan-binding lectin deficiencyArticle Published on 2022-09-142022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] activity Adverse reaction analyzed Anti-SARS-CoV-2 S antibody Antibody Response Autoimmune Autoimmune diseases B-lymphocytes Cell Cohort cohort of patient comparable Course COVID-19 COVID-19 vaccination CVID deficiency detect Disease activity dysfunction effective Efficacy and safety Elecsy flow cytometry healthy control humoral humoral immune response Hypogammaglobulinemia IFN-gamma immune system Immunity immunization immunoassay immunodeficiency immunoglobulin replacement therapy in healthy individuals increased risk individual Interferon-gamma lymphocyte neutralization Patient Phenotyping pneumococcal provide reactogenicity receptor Safe SARS-COV-2 infection selective Seven subjects Support syndrome T cell response T-lymphocites the disease triggering underlying disease vaccination vaccine response Vero E6 Virus neutralization was performed well X-linked agammaglobulinemia XLA [DOI] 10.3389/fimmu.2022.974987 PMC 바로가기
Combining Deep Phenotyping of Serum Proteomics and Clinical Data via Machine Learning for COVID-19 Biomarker DiscoveryCOVID-19 바이오마커 발견을 위한 기계 학습을 통한 혈청 단백질체학 및 임상 데이터의 심층 표현형 결합Article Published on 2022-08-152022-09-11 Journal: International Journal of Molecular Sciences [Category] 바이오마커, 유전자 메커니즘, [키워드] analyzed Biomarker Biomarkers cardiometabolic CD200R1 Central nervous system clinical Clinical practice contributed COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 patient dataset deep disease disease severity Diseases downregulated enrolled Factors IL6 IMPROVE Inflammation KIT LTBP2 lymphocyte lymphocyte counts machine learning MATN3 MCP1 MOST MRAP natural history neurologic neurologic disease neutrophil nine outcome pathology persistence Phenotyping Protective Protein proximity extension assay sera serological data serum biomarker serum biomarkers severe cases small sample size statistical TRANCE unique variable [DOI] 10.3390/ijms23169161 PMC 바로가기 [Article Type] Article