Generation of human TMEM16F-specific affibodies using purified TMEM16FMolecular Biosciences Original Research Published on 2024-01-112024-09-05 Journal: Frontiers in Molecular Biosciences [Category] update2024, [키워드] affibody Biopanning Phospholipids scramblase TMEM16 [DOI] 10.3389/fmolb.2023.1319251 PMC 바로가기 [Article Type] Molecular Biosciences Original Research
MBOAT7 expression is associated with disease progression in COVID-19 patientsOriginal Article Published on 2024-01-062024-09-05 Journal: Molecular biology reports [Category] update2024, [키워드] COVID-19 Inflammation MBOAT7 Phospholipids SARS-CoV-2 [DOI] 10.1007/s11033-023-09009-9 PMC 바로가기 [Article Type] Original Article
Lipidomics Revealed Plasma Phospholipid Profile Differences between Deceased and Recovered COVID-19 PatientsArticle Published on 2022-10-152022-11-15 Journal: Biomolecules [Category] 진단, [키워드] abnormality addition analyzed Anemia appear autoantibody changes characterized control group coronavirus COVID-19 COVID-19 patients CRP level Deceased decrease difference disorder disorders FIVE healthy immune system increase in Increased LDH Lipidomics Liver damage low-density Low-density lipoprotein majority Modification oxidative oxidative stress pathophysiological Patient patients Phosphatidylcholine Phosphatidylserine phospholipid Phospholipids plasma profile profiles Prognostic value recovered recovered patient recovered patients reported Revealed SARS-CoV-2 significantly two subgroup [DOI] 10.3390/biom12101488 PMC 바로가기
Cytidine 5′-Diphosphocholine Corrects Alveolar Type II Cell Mitochondrial Dysfunction in Influenza-infected MiceArticle Published on 2022-06-012023-06-23 Journal: American Journal of Respiratory Cell and Molecular [Category] 신종인플루엔자, [키워드] cardiolipin Glycolysis oxidative phosphorylation Phospholipids [DOI] 10.1165/rcmb.2021-0512OC PMC 바로가기
The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinsesResearch Article Published on 2022-04-152023-06-16 Journal: Journal of Lipid Research [Category] COVID19(2023년), MERS, SARS, [키워드] ACE2, angiotensin-converting enzyme 2 aminophospholipids aPL, aminophospholipid CE, cholesteryl ester Cer, ceramide cetylpyridinium chloride clinical trials CMC, critical micelle concentration Coagulation COVID-19, Coronavirus disease 2019 CPC CPC, cetylpyridinium chloride CUR, curtain gas DHCer, dihydroceramide ER, endoplasmic reticulum GS1, source gas 1 GS2, source gas 2 HILIC, hydrophilic interaction liquid chromatography HSV, Herpes simplex virus Inflammation IPM, isopropyl myristate IS, ionization voltage LAE, ethyl lauroyl arginate Lipidomics LMSD, LIPID MAPS Structure Database Mouthwash MRM, multiple reaction monitoring PC, Phosphatidylcholine PE, Phosphatidylethanolamine PFU, plaque-forming unit PG, phosphatidylglycerol Phospholipids PI, phosphatidylinositol PL, phospholipid PS, phosphatidylserine PVP-I, Povidone-iodine SARS-CoV2, severe acute respiratory syndrome coronavirus 2 SEC, size-exclusion chromatography SL, sphingolipid TAG, triacylglyceride TEM, temperature TG, triglyceride TMPRSS2, Transmembrane serine protease 2 Virology [DOI] 10.1016/j.jlr.2022.100208 PMC 바로가기 [Article Type] Research Article
Lipid biophysics and/or soft matter-inspired approach for controlling enveloped virus infectivityArticle Published on 2022-04-132023-06-23 Journal: Journal of the Royal Society Interface [Category] 신종인플루엔자, [키워드] influenza viruses Membrane biophysics Phospholipids Pulmonary Surfactant soft matter physics [DOI] 10.1098/rsif.2021.0943 PMC 바로가기
PI4-kinase and PfCDPK7 signaling regulate phospholipid biosynthesis in Plasmodium falciparumArticle Published on 2022-02-032024-08-28 Journal: EMBO Reports [Category] 말라리아, [키워드] CDPK kinase malaria Phospholipids Phosphoproteomics Signaling
The roles of lipids in SARS-CoV-2 viral replication and the host immune responseReview Published on 2021-09-292022-10-29 Journal: Journal of Lipid Research [Category] COVID-19, [키워드] AA, arachidonic acid ACE2, angiotensin-converting enzyme 2 acute respiratory syndrome affecting Antiviral strategies ARDS, acute respiratory distress syndrome cell membrane cellular metabolism cholesterol coronavirus COVID-19 cysLT, cysteinyl leukotriene DC, dendritic cell eicosanoid Eicosanoids EPA, eicosapentaenoic acid Host immune response IAV, influenza A virus identify Infection IPr, IP receptor knowledge LA, linoleic acid Lipid lipid composition lipid mediator lipid metabolism Lipidomics LOX, lipoxygenase LPL, lysophospholipid mechanism membrane MERS-CoV, Middle East respiratory syndrome related coronavirus morbidity and mortality NPC1, NPC intracellular cholesterol transporter 1 offer PG, prostaglandin PGI2, prostacyclin Phospholipids receptor regulate RO, replication organelle RSV, respiratory syncytial virus S, spike S1P, sphingosine-1-phosphate SARS-CoV-2 SARS-CoV-2 viral replication SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 SK, sphingosine kinase sphingolipids SR-B1, scavenger receptor B type 1 therapeutic Tx, thromboxane viral burden viral entry viral infection viral life cycle virions virus [DOI] 10.1016/j.jlr.2021.100129 PMC 바로가기 [Article Type] Review
Streptococcus pneumoniae, S. pyogenes and S. agalactiae membrane phospholipid remodelling in response to human serumarticle Published on 2021-05-312024-09-01 Journal: Microbiology [Category] 폐렴구균 감염증, [키워드] cellular membrane Lipidomics Phosphatidylcholine Phospholipids plasmalogen Streptococcus [Article Type] article
Alteration in the Lipid Profile and the Desaturases Activity in Patients With Severe Pneumonia by SARS-CoV-2Physiology Published on 2021-05-112022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] activity acute respiratory syndrome Alter alteration Apoptosis arachidonic acid caused Cell cell membranes change changes in characterized cholesterol COVID-19 COVID-19 patients cytokine release decrease Defense elevated EPA evaluated fatty Fatty acid fatty acids favor HDL Host host cell metabolism host’s cell include increase in inflammatory process LDL Lipid lipid metabolism membrane metabolism mitochondrial membrane modulate Necrosis NEFA NEFAs oxidative stress participated Patient phospholipid Phospholipids plasma Pneumonia profile profiles provided Replication SARS-CoV-2 severe pneumonia Triglyceride Variation viral membrane virus [DOI] 10.3389/fphys.2021.667024 PMC 바로가기 [Article Type] Physiology