A review post-vaccination SARS-CoV-2 serological test: Method and antibody titer responseArticle Published on 2022-12-012022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 진단, [키워드] Antibody titer chemiluminescent immunoassay CLIA CMIA Convalescent plasma therapy Coronavirus disease 2019 COVID-19 Efficacy effort ELISA human donor identify immune response Immune titer immunoassay Lateral LFIA pandemic plaque PRNT reactive SARS-CoV-2 serological serological test Serologist Serologist method serology test Test Vaccine Vaccines [DOI] 10.1016/j.ab.2022.114902 PMC 바로가기
Central nervous system (CNS) inflammatory demyelinating diseases (IDDs) associated with COVID-19: A case series and reviewReview Published on 2022-10-012022-10-05 Journal: Journal of neuroimmunology [Category] COVID19(2023년), SARS, 바이오마커, 진단, 치료기술, [키워드] age Atypical case sery CNS CNS IDD complications condition conducted COVID-19 COVID-19 symptom Descriptive analysis disease disorder female full recovery glycoprotein Google Scholar independent Infection Inflammatory male median MOGAD MS multiple sclerosis nervous system neurological neurological manifestation Neurological symptom NMOSD Optic neuritis; over pathophysiology Patient physician plaque Result SARS-CoV-2 treating COVID-19 patient Treatment Virus-induced demyelination weakness with COVID-19 [DOI] 10.1016/j.jneuroim.2022.577939 [Article Type] Review
Red blood cell distribution width is associated with increased interactions of blood cells with vascular wall Research Published on 2022-08-112022-10-05 Journal: Scientific Reports [Category] 유전자 메커니즘, [키워드] accelerated Affect analyzed animal model applied Artery association Atherosclerosis atherosclerotic lesion Blood blood cell carotid change circulating circulating cell contribute dependent on disease distribution element elevated Flow Hypothesis imaging increased expression Inflammation Interaction Local marker mechanism mouse model pathology Patient plaque poor prognosis Protein red blood cell Red cell researcher resonance subject Variation variety Vascular vessel wall [DOI] 10.1038/s41598-022-17847-z [Article Type] Research
Safety and immunogenicity of intramuscular, single-dose V590 (rVSV-SARS-CoV-2 Vaccine) in healthy adults: Results from a phase 1 randomised, double-blind, placebo-controlled, dose-ranging trial건강한 성인을 대상으로 한 단일 용량 V590(rVSV-SARS-CoV-2 Vaccine)의 근육 내 안전성 및 면역원성: 1상 무작위 배정, 이중 맹검, 위약 대조, 용량 범위 시험 결과Clinical Trial Published on 2022-08-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료법, [키워드] Administered administration Adults adverse event adverse events AEs anti-SARS-CoV-2 Antibody responses comparable COVID-19 COVID-19 vaccine Day dose double-blind Endpoint fatigue global pandemic headache healthy highest dose immunogenicity Inc. Injection-site pain intramuscular lower dose neutralisation neutralising antibody response Older overcome Part participant pfu Phase 1 phase 1 study Placebo placebo-controlled plaque plaque-forming unit plaque-forming units primary endpoints PRNT50 randomised receive reduction Registration reported Result Safety SARS-CoV-2 SARS-CoV-2 nucleocapsid seronegative seronegative participant seronegative participants seropositive serum Sharp spike-specific antibody response stomatitis subsidiary Trial USA V590 Vaccine vesicular stomatitis vesicular stomatitis virus vesicular stomatitis virus (VSV) virus VSV [DOI] 10.1016/j.ebiom.2022.104138 PMC 바로가기 [Article Type] Clinical Trial
A randomized, placebo-controlled clinical trial evaluating of a mouthwash containing Sambucus williamsii var. coreana extract for prevention of gingivitits Research Published on 2022-07-182022-10-05 Journal: Scientific Reports [Category] 임상, [키워드] applicability assigned Bacteria Care carried conducted Day disease double-blind effective experiment Health healthy homogeneity IBM inhibiting maintain participant patients placebo-controlled clinical trial placebo-controlled study plaque plaques progression Randomized saline solution Sambucus shown significant difference SPSS 24.0 study period two groups USA using a mouthwash VAR was used window [DOI] 10.1038/s41598-022-15445-7 [Article Type] Research
Rapid self-test of unprocessed viruses of SARS-CoV-2 and its variants in saliva by portable wireless graphene biosensor휴대용 무선 그래핀 바이오센서를 통한 타액 내 처리되지 않은 SARS-CoV-2 바이러스 및 그 변이체의 신속한 자가 테스트Article Published on 2022-07-122022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus aptamer biosensor clinically Cognate Concentration coronavirus COVID-19 D614G detect determined by diagnostic DNA domain early phase environmental monitoring epidemiological epidemiologically field-effect transistor Graphene limit limit of detection LoQ MERS Middle East Middle East respiratory syndrome N protein N501Y nucleocapsid omicron pandemic plaque plaque-forming unit platform positive Precision Protein Proteins public health quantitation Rapid RBD Receptor-binding domain respiratory RT-PCR S protein Saliva saliva samples SARS-CoV-2 SARS-CoV-2 variant sensitivity sensor severe acute respiratory syndrome coronavirus 2 significantly lower specificity Spike protein statistically variant variants of concern viral particle Viral particles Viral proteins virus Y453F [DOI] 10.1073/pnas.2206521119 PMC 바로가기 [Article Type] Article
RBD decorated PLA nanoparticle admixture with aluminum hydroxide elicit robust and long lasting immune response against SARS-CoV-2수산화알루미늄이 포함된 RBD 장식 PLA 나노입자 혼합물은 SARS-CoV-2에 대한 강력하고 오래 지속되는 면역 반응을 이끌어냅니다.Article Published on 2022-07-012022-09-12 Journal: European journal of pharmaceutics and biopharmaceu [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome aluminum antibody Antibody Response Antigen binding caused Characteristics circumvent Combination coronavirus COVID-19 COVID-19 vaccine develop E. coli elicit elicited expressed expression generate global pandemic hydroxide immune response immunization lactic acid limitations long-lasting mammalian memory Memory antibody response mimicking neutralization neutralize plaque Polymeric nanoparticles Protein-subunit vaccine provided RBD Receptor binding domain Result robust SARS-CoV-2 SARS-CoV-2 vaccine secondary antibody subunit Subunit vaccine Th1 Th2 Vaccine vaccine production virus infection Virus neutralization [DOI] 10.1016/j.ejpb.2022.05.008 PMC 바로가기 [Article Type] Article
Influence of SARS-CoV-2 inactivation by different chemical reagents on the humoral response evaluated in a murine model쥐 모델에서 평가된 체액 반응에 대한 다양한 화학 시약에 의한 SARS-CoV-2 비활성화의 영향Article Published on 2022-07-012022-09-12 Journal: Molecular immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition Administered anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Antigen antigenic biosafety Brazil cell culture supernatant Cytopathic effect ELISA ELISA assay evaluate evaluated expressive formaldehyde glutaraldehyde highest humoral IgG immunization immunized immunogen inactivated Inactivated virus inactivation influence mice murine model Neutralizing neutralizing antibody observation pandemic plaque polymerase chain PRNT PRNT(50) protocol purified quantification reagent real time risk RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 viral subsequent Test the SARS-CoV-2 Toxicity Treatment verification Vero cells Viral antigen viral inactivation Viral protein virus was performed [DOI] 10.1016/j.molimm.2022.05.012 PMC 바로가기 [Article Type] Article
Worsening hearing was associated with higher β-amyloid and tau burden in age-related hearing loss Research Published on 2022-06-212022-10-05 Journal: Scientific Reports [Category] 바이오마커, 진단, [키워드] 95% CI adjusted Affect age Alzheimer’s disease association Brain calculated cardiovascular disease cohort study confidence interval covariate covariates cross-sectional Dementia Evidence exhibited Gender hallmark hearing loss Linear regression pathologic pathologic hallmark Patient performed pet plaque potential risk predict Research resulting the mean tomography was measured was related was used were measured worsening [DOI] 10.1038/s41598-022-14466-6 [Article Type] Research
Chemical profiling and unraveling of anti-COVID-19 biomarkers of red sage (Lantana camara L.) cultivars using UPLC-MS/MS coupled to chemometric analysis, in vitro study and molecular docking화학 측정 분석, 시험관 내 연구 및 분자 도킹과 결합된 UPLC-MS/MS를 사용하여 레드 세이지(Lantana camara L.) 품종의 항-COVID-19 바이오마커의 화학적 프로파일링 및 해명Article Published on 2022-06-122022-09-11 Journal: Journal of ethnopharmacology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술, 치료제, [키워드] (RdRp acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis anti-COVID-19 activity. antiviral activity approach Asia Biomarker Biomarkers Brazil Candidates Chain Reaction Chemical chemometrics Compound Concentration coronavirus COVID-19 cytotoxicity Data analysis detect determine docked docking docking score E-gene Effect Efficacy except for exhibited exhibiting expression expression levels flavonoids flower followed by highest in vitro study In-vitro India infections inhibitor inhibitory activity interaction pattern Kenya Lantana Lantana camara L. cultivars leprosy Luteolin material mechanism metabolites metabolomics molecular docking multivariate Multivariate analysis Nigeria PCA PCA plot PCA plots plaque polymerase chain polymerase chain reaction principle profile progressed RdRP RdRp gene real-time RT-PCR Red Remdesivir required respiratory respiratory diseases respiratory virus respiratory viruses reverse transcription polymerase chain reaction rheumatism RNA-dependent RNA polymerase RT-PCR SARS-CoV-2 selectivity indices severe acute respiratory syndrome Coronavirus Spread spreading Structure sunset TaqMan target tested Transcription UPLC UPLC-MS/MS Verbenaceae Viral [DOI] 10.1016/j.jep.2022.115038 PMC 바로가기 [Article Type] Article