In silico validation of novel inhibitors of malarial aspartyl protease, plasmepsin V and antimalarial efficacy predictionArticle Published on 2022-11-302024-09-10 Journal: J Biomol Struct Dyn [Category] 말라리아, [키워드] antimalarial drug design in silico Plasmepsin PMC 바로가기
Bridging the Gap in Malaria Parasite Resistance, Current Interventions, and the Way Forward from in Silico Perspective: A ReviewArticle Published on 2022-11-162024-08-29 Journal: Molecules [Category] 말라리아, [키워드] computer-aided drug design (CADD) malaria Parasite resistance Plasmepsin Plasmodium falciparum
Exploration of copy number variation in genes related to anti-malarial drug resistance in Plasmodium falciparumarticle Published on 2020-04-302024-09-01 Journal: Gene [Category] 말라리아, [키워드] adaptation Anti-malarial drug resistance copy number variation P. falciparum Plasmepsin [Article Type] article
Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle이중 플라스메프신 표적 항말라리아 제제가 말라리아 기생충 생애 주기의 여러 단계를 방해합니다.Article Published on 2020-04-082024-08-26 Journal: Cell Host & Microbe [Category] 말라리아, [키워드] antimalarial humanized mouse malaria Merozoite Plasmepsin plasmepsin IX plasmepsin X Plasmodium [DOI] 10.1016/j.chom.2020.02.005 PMC 바로가기 [Article Type] Article
Antimalarials: Review of Plasmepsins as Drug Targets and HIV Protease Inhibitors Interactionsarticle Published on 2019-12-312024-09-01 Journal: Current Topics in Medicinal Chemistry [Category] 말라리아, [키워드] Antimalarials HIV protease inhibitors malaria P. falciparum P. vivax drug targets Plasmepsin [Article Type] article
Plerixafor and related macrocyclic amines are potential drug candidates in treatment of malaria by “filling the flap” region of plasmepsin enzymesarticle Published on 2018-09-302024-09-01 Journal: Med Hypotheses [Category] 말라리아, [키워드] heme hemoglobin macrocycle malaria Plasmepsin Plerixafor [Article Type] article
Plasmodium berghei plasmepsin VIII is essential for sporozoite gliding motilityarticle Published on 2017-04-302024-09-01 Journal: International Journal for Parasitology [Category] 말라리아, [키워드] Gliding motility Invasion malaria oocyst Plasmepsin Plasmodium [Article Type] article
Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X말라리아 원충 파르시파룸의 우키네트에서 플라스메프신 VII 및 플라스메프신 X의 발현Research Published on 2016-02-242024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] aspartic protease Biochemistry Cell Biology Gene Expression Plasmepsin Plasmodium falciparum transcriptomics transmission-blocking [DOI] 10.1186/s12936-016-1161-5 PMC 바로가기 [Article Type] Research
Malaria proteomics: insights into the parasite-host interactions in the pathogenic spacearticle Published on 2014-01-312024-09-01 Journal: Journal of Proteomics [Category] 말라리아, [키워드] 2-D Fluorescence Difference Gel Electrophoresis 2D-DIGE 2D-nanoflow high-performance liquid chromatography 2D-nanoLC 2D-PAGE 4-HNE 4-hydroxy-2-nonenal Apical sushi protein ASP G6PD GBA glucose-6-phosphate dehydrogenase glycosylphosphatidylinositol GPF GPI Green-fluorescent protein Guilt by association heat shock protein Heat shock protein-70 HSP Hsp70 immunomics infected red blood cells iRBCs malaria Merozoite surface protein MSP MudPIT Multidimensional protein identification Pathogenic space PKA Plasmepsin Plasmepsin II PM PM-II post-translational modifications protein kinase A proteomics PTMs ramA RBC reactive oxygen species red blood cell Rhoptry-associated membrane antigen ROS sera Serine repeat antigen Subproteome two-dimensional gel electrophoresis [Article Type] article