No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China–Myanmar border중국-미얀마 국경 지역에서 아르테미시닌 내성 말라리아와 관련하여 증폭된 Plasmodium falciparum plasmepsin II 유전자 복제 수의 증거가 없음Research Published on 2020-09-142024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] Artemisinin resistance China–Myanmar border Piperaquine Plasmepsin II Plasmodium falciparum [DOI] 10.1186/s12936-020-03410-6 PMC 바로가기 [Article Type] Research
Are k13 and plasmepsin II genes, involved in Plasmodium falciparum resistance to artemisinin derivatives and piperaquine in Southeast Asia, reliable to monitor resistance surveillance in Africa?K13 및 플라스메프신 II 유전자가 동남아시아에서 아르테미시닌 유도체와 피페라퀸에 대한 플라스모디움 팔시파룸의 저항성과 관련이 있다면, 아프리카에서 저항성 감시를 모니터링하는 데 신뢰할 수 있는가?Opinion Published on 2019-08-232024-08-11 Journal: Malaria Journal [Category] 말라리아, [키워드] anti-malarial drug dihydroartemisinin in vitro K13 malaria Piperaquine Plasmepsin II Plasmodium falciparum resistance [DOI] 10.1186/s12936-019-2916-6 PMC 바로가기 [Article Type] Opinion
Baseline Ex Vivo and Molecular Responses of Plasmodium falciparum Isolates to Piperaquine before Implementation of Dihydroartemisinin-Piperaquine in SenegalArticle Published on 2019-04-252024-08-28 Journal: Med Instrum [Category] 말라리아, [키워드] antimalarial drug in vitro malaria Molecular marker Piperaquine Plasmepsin II Plasmodium falciparum resistance
Synthesis, characterization, molecular docking and in vitro antimalarial properties of new carboxamides bearing sulphonamidearticle Published on 2017-07-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] antimalarial antioxidant Carboxamides Plasmepsin II SAR Sulphonamides [Article Type] article
New paradigm of an old target: an update on structural biology and current progress in drug design towards plasmepsin IIarticle Published on 2015-05-312024-09-01 Journal: European Journal of Medicinal Chemistry [Category] 말라리아, [키워드] aspartic protease Drug discovery malaria peptidomimetics Plasmepsin II Protease inhibitor [Article Type] article
Malaria proteomics: insights into the parasite-host interactions in the pathogenic spacearticle Published on 2014-01-312024-09-01 Journal: Journal of Proteomics [Category] 말라리아, [키워드] 2-D Fluorescence Difference Gel Electrophoresis 2D-DIGE 2D-nanoflow high-performance liquid chromatography 2D-nanoLC 2D-PAGE 4-HNE 4-hydroxy-2-nonenal Apical sushi protein ASP G6PD GBA glucose-6-phosphate dehydrogenase glycosylphosphatidylinositol GPF GPI Green-fluorescent protein Guilt by association heat shock protein Heat shock protein-70 HSP Hsp70 immunomics infected red blood cells iRBCs malaria Merozoite surface protein MSP MudPIT Multidimensional protein identification Pathogenic space PKA Plasmepsin Plasmepsin II PM PM-II post-translational modifications protein kinase A proteomics PTMs ramA RBC reactive oxygen species red blood cell Rhoptry-associated membrane antigen ROS sera Serine repeat antigen Subproteome two-dimensional gel electrophoresis [Article Type] article