Chemical Adjustment of FibrinolysisOpinion Published on 2024-01-102024-09-05 Journal: Pharmaceuticals [Category] update2024, [키워드] FIBRIN Ischemic Stroke plasmin Thrombolysis tissue plasminogen activator [DOI] 10.3390/ph17010092 PMC 바로가기 [Article Type] Opinion
Plasmodium falciparum Gametes and Sporozoites Hijack Plasmin and Factor H To Evade Host Complement KillingArticle Published on 2023-06-152024-08-28 Journal: Microbiol Spectr [Category] 말라리아, [키워드] complement complement evasion Gamete malaria plasmin sporozoite Transmission
Pneumococcal proteins ClpC and UvrC as novel host plasminogen binding factorsarticle Published on 2023-02-282024-09-01 Journal: Microbiology and Immunology [Category] 폐렴구균 감염증, [키워드] Autolysin ClpC plasmin plasminogen Streptococcus pneumoniae UvrC virulence strategy [Article Type] article
Competitive cleavage of SARS-CoV-2 spike protein and epithelial sodium channel by plasmin as a potential mechanism for COVID-19 infectionArticle Published on 2022-11-012023-07-10 Journal: American journal of physiology. Lung cellular and [Category] COVID19(2023년), [키워드] COVID-19 Epithelial sodium channels furin site plasmin SARS-CoV-2 Spike protein [DOI] 10.1152/ajplung.00152.2022 PMC 바로가기
Insight towards the effect of the multi basic cleavage site of SARS-CoV-2 spike protein on cellular proteasesArticle Published on 2022-06-062022-11-01 Journal: Virus research [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] acute respiratory syndrome Amino acid amino acid substitution Analysis analyzed Antiviral approach binding cathepsin B cell receptor cellular cellular protease cellular proteases cleavage site cleaving coronavirus coronavirus pathogenesis develop domain functional furin furin cleavage site generate Health help Host host cell protease host protease host range incorporation indicated Infection inhibitor insight Interaction involved maturation MD simulation MD simulations molecular molecular docking multi Mutation plasmin polybasic primary determinant protease Protein proteolytic activation Receptor binding S protein S1 and S2 SARS-CoV-2 SARS-CoV-2 spike protein shown spike Spike protein Spread subunits the S protein tissue tropism [DOI] 10.1016/j.virusres.2022.198845 PMC 바로가기 [Article Type] Article
Associations between hemostatic markers and mortality in COVID-19 – Compounding effects of D-dimer, antithrombin and PAP complexCOVID-19에서 지혈 마커와 사망률 사이의 연관성 - D-dimer, antithrombin 및 PAP 복합체의 복합 효과Article Published on 2022-05-012022-09-11 Journal: Thrombosis research [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] 95% confidence interval Antithrombin applied Coagulation cohort study complex compounding consecutive patient COVID-19 cumulative D-dimer death dimer Effect elevated excess mortality FIBRIN fibrinogen fibrinolysis fibrinolytic fraction hemostatic function incidence increases in Laboratory Linköping marker Mortality Odds ratio Odds ratios Patient patients plasma Plasma levels plasmin Plasmin-antiplasmin complex. positive SARS-CoV-2 single-center tested university Venous Thromboembolism von Willebrand factor [DOI] 10.1016/j.thromres.2022.03.013 PMC 바로가기 [Article Type] Article
Beyond cuts and scrapes: plasmin in malaria and other vector-borne diseasesarticle Published on 2022-02-282024-09-01 Journal: Trends in Parasitology [Category] 말라리아, [키워드] fibrinolysis malaria plasmin vector-borne diseases [Article Type] article
The Impact of Age and BMI on the VWF/ADAMTS13 Axis and Simultaneous Thrombin and Plasmin Generation in Hospitalized COVID-19 PatientsMedicine Published on 2022-01-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ADAMTS13 addition age aging Analysis analyzed Antigen axis binding activity BMI body mass index Coagulation Coagulopathy collagen collected conditions contribute contributed Corona COVID-19 COVID-19 negative cross-sectional elevated endothelial Endothelial dysfunction factor VIII Generation Health hospital Impact increases in increasing age individual obesity Older parameter Patient plasma plasmin populations positive reduced risk severity Simultaneous thrombin von Willebrand factor vWF [DOI] 10.3389/fmed.2021.817305 PMC 바로가기 [Article Type] Medicine
Thromboplasminflammation in COVID-19 Coagulopathy: Three Viewpoints for Diagnostic and Therapeutic StrategiesImmunology Published on 2021-06-112022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] activate activated acute respiratory syndrome Ang II angiotensin-converting enzyme 2 anticoagulation bleeding candidate cause circulation Coagulation Coagulopathy complement pathways condition coronavirus coronavirus disease COVID-19 critically ill patients death disseminate Disseminated intravascular coagulation DNA downregulate drug endothelial injury Endothelium exacerbate expression immunothrombosis include increase in induce Infection Inflammation Inflammatory cytokines Lungs Microvascular thrombosis molecular mechanism multiple organ dysfunction NET Neutrophil extracellular trap pathology plasmin platelet activation Prognosis receptor required resulting robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA serine protease Strategy systemic inflammation target thrombin thrombosis Treatment [DOI] 10.3389/fimmu.2021.649122 PMC 바로가기 [Article Type] Immunology
COVID-19 and sepsis are associated with different abnormalities in plasma procoagulant and fibrinolytic activityArticle Published on 2021-02-122023-06-16 Journal: Arteriosclerosis, Thrombosis, and Vascular Biology [Category] MERS, SARS, [키워드] COVID-19 fibrinogen plasmin Sepsis thrombin [DOI] 10.1161/ATVBAHA.120.315338 PMC 바로가기 [Article Type] Article