Inhibition of SARS-CoV-2 Nsp9 ssDNA-Binding Activity and Cytotoxic Effects on H838, H1975, and A549 Human Non-Small Cell Lung Cancer Cells: Exploring the Potential of Nepenthes miranda Leaf Extract for Pulmonary Disease TreatmentArticle Published on 2024-06-012024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] anticancer AntoDock lupenone Nepenthes NSCLC Nsp9 Plumbagin SARS-CoV-2 stigmast-5-en-3-ol [DOI] 10.3390/ijms25116120 PMC 바로가기 [Article Type] Article
Medical Significance of Uterine Corpus Endometrial Carcinoma Patients Infected With SARS-CoV-2 and Pharmacological Characteristics of PlumbaginSARS-CoV-2에 감염된 자궁체부 자궁내막암 환자의 의학적 의의 및 Plumbagin의 약리학적 특성Endocrinology Published on 2021-10-122022-09-11 Journal: Frontiers in Endocrinology [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis Anti-inflammation Anti-inflammatory Apoptosis bioinformatics Cancer candidate clinical Clinical characteristics conducted coronavirus coronavirus disease corpus COVID-19 COVID-19 in patient cytotoxicity disease Effect Endometrial Carcinoma Evidence functions Genes Health identify immunomodulating immunomodulation in silico in silico analysis In silico method infected with SARS-CoV-2 inhibitor MAPK3 mechanism mechanism and characterization mitogen mitogen-activated protein kinase modulation molecular molecular docking molecular docking analysis Necrosis network network pharmacology pathway Patient pharmacologic (drug) therapy pharmacological PLAU Plumbagin Potential treatment prognostic proliferation Protein protein kinase respiratory Result risk SARS-CoV-2 Screen severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Significance survival rate target targets TNF Treatment Tumor tumor necrosis tumor necrosis factor Urokinase-Type Plasminogen Activator uterine [DOI] 10.3389/fendo.2021.714909 PMC 바로가기 [Article Type] Endocrinology
Perspectives on mechanistic implications of ROS inducers for targeting viral infections바이러스 감염을 표적으로 하는 ROS 유도제의 기계론적 의미에 대한 관점Article Published on 2021-01-052022-09-11 Journal: European journal of pharmacology [Category] SARS, 치료제, [키워드] antioxidant Antiviral antiviral drug antiviral drugs Corona Corona virus COVID-19 Degradation determine drug candidates exhibit experimental validation faster global pandemic Host host cells Hypothesis impair implication induce inducer lead macromolecules oxidants oxygen pandemic Perspective Plumbagin reactive oxygen species reactive oxygen specy redox potential Replication reported respiratory RNA RNA degradation RNAs ROS ROS inducers SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome corona virus-2 shifting therapeutic therapeutic strategy Treatment Viral viral entry viral infection viral infections Viral RNA Virus Disease Virus Disease - [DOI] 10.1016/j.ejphar.2020.173621 PMC 바로가기 [Article Type] Article
Plumbagin, a vitamin K3 analogue ameliorate malaria pathogenesis by inhibiting oxidative stress and inflammationarticle Published on 2018-08-312024-09-01 Journal: InflammoPharmacology [Category] 말라리아, [키워드] Inflammation malaria mice oxidative stress Plumbagin [Article Type] article
Potential mode of action of a novel plumbagin as a mosquito repellent against the malarial vector Anopheles stephensi, (Culicidae: Diptera)article Published on 2016-11-302024-09-01 Journal: Hospitals [Category] 말라리아, [키워드] enzyme FT-IR histology Malarial vector NMR Plumbagin [Article Type] article
Application of SPECT/CT imaging system and radiochemical analysis for investigation of blood kinetics and tissue distribution of radiolabeled plumbagin in healthy and Plasmodium berghei-infected micearticle Published on 2016-02-282024-09-01 Journal: Endocrine [Category] 말라리아, [키워드] biodistribution Plumbagin SPECT/CT imaging system Technetium-99m [Article Type] article
Antimalarial activity of plumbagin in vitro and in animal models플럼바진의 항말라리아 활성 in vitro 및 동물 모델에서Research Article Published on 2014-01-122024-08-13 Journal: BMC Complementary and Alternative Medicine [Category] 말라리아, [키워드] antimalarial Plasmodium berghei Plasmodium falciparum Plumbagin [DOI] 10.1186/1472-6882-14-15 PMC 바로가기 [Article Type] Research Article