Pneumococcal sialidase promotes bacterial survival by fine-tuning of pneumolysin-mediated membrane disruption폐렴구균 시알리다아제가 폐렴리신 매개 막 파괴의 미세 조정을 통해 세균 생존을 촉진한다.Article Published on 2024-03-262024-08-24 Journal: Cell Reports [Category] 폐렴구균 감염증, [키워드] CP: Cell biology CP: Microbiology cytotoxicity endosome disrupture NanA NanoBiT nanobody oseltamivir Pneumolysin sialic acid Streptococcus pneumoinae Xenophagy
Estimates of differential toxin expression governing heterogeneous intracellular lifespans of Streptococcus pneumoniae스트렙토코쿠스 뉴모니아의 이질적인 세포 내 수명을 지배하는 차별적 독소 발현 추정치Article Published on 2024-02-152024-08-24 Journal: Journal of Cell Science [Category] 폐렴구균 감염증, [키워드] autophagy First-passage process galectin Pneumolysin Pore formation. Streptococcus pneumoniae
Isorhamnetin as a novel inhibitor of pneumolysin against Streptococcus pneumoniae infection in vivo/in vitroarticle Published on 2023-12-312024-09-01 Journal: Microbial Pathogenesis [Category] 폐렴구균 감염증, [키워드] anti-infection Anti-virulence isorhamnetin Pneumolysin Streptococcus pneumoniae [Article Type] article
Recent progress in pneumococcal protein vaccinesarticle Published on 2023-09-302024-09-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] pneumococcal histidine triad proteins Pneumococcal protein vaccine pneumococcal surface proteins Pneumolysin Streptococcus pneumoniae [Article Type] article
Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors혈액과 미세소포의 응고촉진 활성이 폐렴구균 폐렴용해소에 의해 방해받으며, 이는 응고 인자와 상호작용한다.Article Published on 2023-07-152024-08-23 Journal: Journal of Innate Immunity [Category] 폐렴구균 감염증, [키워드] Coagulation contact system Microvesicles Pneumolysin [DOI] 10.1159/000525479 PMC 바로가기
The Global Burden of Community-Acquired Pneumonia in Adults, Encompassing Invasive Pneumococcal Disease and the Prevalence of Its Associated Cardiovascular Events, with a Focus on Pneumolysin and Macrolide Antibiotics in Pathogenesis and Therapy성인에서의 지역사회 획득 폐렴의 세계적 부담, 침습성 폐렴구균 질환과 관련 심혈관 사건의 유병률을 포함하여, 병인 및 치료에서 폐렴독소와 마크로라이드 항생제에 초점을 맞춘 연구Article Published on 2023-07-032024-08-24 Journal: International Journal of Molecular Sciences [Category] 폐렴구균 감염증, [키워드] Cardiovascular events community-acquired pneumonia dendritic cells macrolides macrophages mannose receptor C-type1 Platelets Pneumolysin pro-inflammatory cytokines Streptococcus pneumoniae
Therapeutic potential of kaempferol on Streptococcus pneumoniae infection켐페롤의 폐렴구균 감염에 대한 치료 잠재력Article Published on 2023-03-012023-07-10 Journal: Microbes and infection [Category] COVID19(2023년), 폐렴구균 감염증, [키워드] Anti-virulence kaempferol Pneumolysin sortase A Streptococcus pneumoniae [DOI] 10.1016/j.micinf.2022.105058 PMC 바로가기
Construction and protective efficacy of a novel Streptococcus pneumoniae fusion protein vaccine NanAT1-TufT1-PlyD4article Published on 2022-10-312024-09-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] Bioinformatics analysis Elongation factor Tu fusion protein vaccine neuraminidase A Pneumolysin Streptococcus pneumoniae [Article Type] article
Corilagin: A Novel Antivirulence Strategy to Alleviate Streptococcus pneumoniae Infection by Diminishing Pneumolysin Oligomers코릴라진: 폐렴구균 감염을 완화하기 위한 새로운 항독소 전략으로, 폐렴용해소체 올리고머를 감소시킴.Article Published on 2022-08-092024-08-24 Journal: Molecules [Category] 폐렴구균 감염증, [키워드] antivirulence Corilagin molecular docking Pneumolysin Streptococcus pneumoniae
Protective role of Cav-1 in pneumolysin-induced endothelial barrier dysfunctionarticle Published on 2022-07-312024-09-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] barrier-function calcium-influx caveolin-1 endocytosis Pneumolysin [Article Type] article