A Systematic Review and Meta-Analysis of Serotype Distribution of Streptococcus Pneumoniae in Iran: Practical Evidence to Optimizing Local Vaccination Protocolsarticle Published on 2021-12-312024-09-01 Journal: Infectious Disorders - Drug Targets [Category] 폐렴구균 감염증, [키워드] invasive diseases pneumococcal polysaccharide capsule serotype Streptococcus pneumoniae Vaccine [Article Type] article
Examining the Distribution and Impact of Single-Nucleotide Polymorphisms in the Capsular Locus of Streptococcus pneumoniae Serotype 19A폐렴구균 19A형의 캡슐 유전자 위치에서 단일 뉴클레오타이드 다형성의 분포 및 영향 조사Article Published on 2021-07-122024-07-30 Journal: Infection and Immunity [Category] 폐렴구균 감염증, [키워드] capsule shedding Dutch cohort polysaccharide capsule serotype 19A Streptococcus pneumoniae whole-genome sequencing [DOI] 10.1128/IAI.00246-21 PMC 바로가기
Pleiotropy and epistasis within and between signaling pathways defines the genetic architecture of fungal virulence신호 전달 경로 내 및 사이의 다면발광 및 상위성은 진균 독성의 유전적 구조를 정의합니다Research Article Published on 2021-01-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affect amphotericin B Analysis antifungal drug resistance approach Author avirulent body temperature CAMP cascade Cell Cell signaling cellular cellular response Cellular responses characterization Combination complex component contribute cross Cryptococcal disease Cryptococcus cyclic AMP disease drug susceptibility drugs ENCODE epistatic interaction Europe Extracellular fungal Genes Genetic genetic architecture genetic difference genetic differences Genetic variation glycerol growth highlight human body Infection information isolate kinase Lineage locus make up mapping microbial modify molecular nucleotide osmolarity osmotic oxidative oxidative stress oxidative stress resistance pathogen pathogenicity Pathogens pathway phenotypic phenotypic variation physiological response pleiotropic polysaccharide capsule progeny promote protein kinase QTL Quantitative quantitative trait locus regulate regulator sensitivity Signal transduction Signaling signaling pathway strain Strains Stress temperate climates thought Tolerance traits underlie Variation virulence virulent [DOI] 10.1371/journal.pgen.1009313 PMC 바로가기 [Article Type] Research Article
Putative novel cps loci in a large global collection of pneumococci대규모 전 세계 폐렴구균 집합체에서의 가설적 새로운 cps 유전자 좌위Article Published on 2019-07-112024-07-31 Journal: Microbial Genomics [Category] 폐렴구균 감염증, [키워드] cps locus pneumococcus polysaccharide capsule serotype Streptococcus pneumoniae [DOI] 10.1099/mgen.0.000274 PMC 바로가기
Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes모든 90개의 폐렴구균 혈청형에서 피막 생합성 유전자좌의 유전적 분석Research Article Published on 2006-03-102022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 폐렴구균 감염증, [키워드] Analysis antigenic variation Antisera bacterial pathogen bacterial polysaccharide bacterial polysaccharide biosynthesis system bacterial polysaccharide diversity Bentley Blood capsular biosynthesis capsular biosynthesis gene capsular biosynthesis genes capsular biosynthetic gene capsular biosynthetic genes capsular gene capsular polysaccharide capsular polysaccharide structures capsular polysaccharides capsular serotype Capsule children chromosomal coated coding complement Complete determined different disease DNA DNA sequence effective protein-conjugated Effective vaccines evade Evolution Express genetics host antibodies host antibody human immune response immunochemically immunogenic immunological reactivity introduced invasive bacterial pathogen knowledge locus mechanism molecular Pathogens pneumococcal disease pneumococcus polysaccharide capsule polysaccharide structure polysaccharide vaccine PROTECT S. pneumoniae selected sequence sequences sera serological profile serological profiles serotype serotypes Seven Streptococcus pneumoniae survival target The United States total size United States virulence [DOI] 10.1371/journal.pgen.0020031 PMC 바로가기 [Article Type] Research Article