Effectiveness of COVID-19 vaccination in healthcare workers in Shiga Prefecture, JapanArticle Published on 2022-10-212022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 진단, [키워드] Abbott analyzed antibody Cell cells Cellular immune response cellular immunity conducted coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccinations Delta effective evaluated HCW HCWs health condition healthcare worker Hospitalization humoral induce Japan Poor questionnaire repeated required Roche SARS-CoV-2 SARS-COV-2 infection serological seropositive Standard deviation vaccination Vaccine Wuhan-1 [DOI] 10.1038/s41598-022-22682-3 PMC 바로가기
Poor vaccine responsiveness towards third-dose mRNA vaccine of COVID-19 in Japanese older peopleArticle Published on 2022-10-012022-11-15 Journal: The Journal of Infection [Category] Fulltext, MERS, 진단, [키워드] Abstract acute respiratory syndrome antibody coronavirus Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 Japanese mRNA vaccine Older Poor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Vaccine vaccine booster Vaccine failure Vaccine failure. [DOI] 10.1016/j.jinf.2022.07.007 PMC 바로가기
Poor Antibody Response to BioNTech/Pfizer Coronavirus Disease 2019 Vaccination in Severe Acute Respiratory Syndrome Coronavirus 2-Naive Residents of Nursing HomesBioNTech/Pfizer 코로나바이러스 질병 2019 중증 급성 호흡기 증후군 코로나바이러스 백신 접종에 대한 항체 반응 불량Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus administration age antibody Antibody Response B.1.351 B.1.351 variant Belgium binding antibodies binding antibody BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination Breakthrough infection cluster analysis comorbid conditions comparable coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death detectable disease domain domains dose General population heterogeneity high risk home immunization Immunoglobulin immunosenescence IMPROVE in some Infection involved Messenger RNA mRNA mRNA vaccination mRNA vaccine Neutralizing Nursing nursing homes nursing homes. old age Poor RBD RBD IgG recruited related disease resident respiratory respond poorly Responder response S1 and S2 SARS-CoV-2 severe acute respiratory syndrome Coronavirus Support the vaccine These data vaccination Vaccine vaccine strain variants variants of concern were assessed wild type [DOI] 10.1093/cid/ciab998 PMC 바로가기 [Article Type] Article
Poor Response to Inactivated SARS-CoV-2 Vaccine in Patients With Chronic Liver Disease만성 간 질환 환자에서 비활성화된 SARS-CoV-2 백신에 대한 낮은 반응Comment Published on 2022-08-012022-09-12 Journal: Clinical gastroenterology and hepatology : the off [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] chronic Poor response SARS-CoV-2 [DOI] 10.1016/j.cgh.2022.01.029 PMC 바로가기 [Article Type] Comment
Defining Clinical and Immunological Predictors of Poor Immune Responses to COVID-19 mRNA Vaccines in Patients with Primary Antibody DeficiencyArticle Published on 2022-08-012022-11-15 Journal: Journal of Clinical Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] anti-S IgG antibody association Autoimmunity B-cells baseline CD19 CD4 CD8 Cellular immune response clinical Cohort common common variable immune deficiency coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 mRNA vaccines criteria CVID deficiency develop Diagnosis disease dose expression Frequency HCs humoral IgA IgG IgG deficiency IgG subclasse immune Immune profile immunological characteristics impairment investigated memory Moderna Moderna mRNA vaccine mRNA mRNA vaccine naïve neutralization activity OX40 Patient Pfizer-BioNTech Pfizer-BioNTech mRNA vaccine Poor predicted primary antibody primary antibody deficiency response responses SARS-CoV-2 spike protein Selective IgG subclass deficiency significantly lower Specific Specific antibody deficiency. subset T-cell T-cell Response T-cells vaccination Vaccine vaccine response [DOI] 10.1007/s10875-022-01296-4 PMC 바로가기
COVID-19 Severity and Mortality in Two Pandemic Waves in Poland and Predictors of Poor Outcomes of SARS-CoV-2 Infection in Hospitalized Young Adults폴란드의 두 가지 유행성 전염병의 COVID-19 심각도 및 사망률과 입원한 젊은 성인의 SARS-CoV-2 감염의 나쁜 결과 예측Article Published on 2022-07-312022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] addition Adults adults hospitalized albumin Alpha Alpha variant analyzed blood cell blood cell counts C-reactive protein calcium Characteristics Clinical characteristics Comorbidities COVID-19 COVID-19 severity creatine creatine kinase creatinine D-dimer debatable decrease disease severity Factors filtration rate global public health glomerular filtration rate had no hematocrit hemoglobin Hospitalization identify increase in intensive care intensive care unit treatment interleukin interleukin-6 investigated Laboratory Lactate lactate dehydrogenase Leukocytosis Logistic regression lung involvement lymphocyte lymphopenia mechanical ventilation Mortality Myoglobin neutrophil Neutrophil-to-lymphocyte ratio neutrophilia no increase non-survivor obesity outcome pandemic Patient peptide performed Poland Poor predictor predictors procalcitonin red blood cell Retrospective study risk of death SARS-CoV-2 SARS-CoV-2 variants second wave severe COVID-19 severity survivor Treatment troponin I urea variant Vitamin Vitamin D3 Wave with COVID-19 Young adults. [DOI] 10.3390/v14081700 PMC 바로가기 [Article Type] Article
Multiplex protein profiling of bronchial aspirates reveals disease-, mortality- and respiratory sequelae-associated signatures in critically ill patients with ARDS secondary to SARS-CoV-2 infection기관지 흡인물의 다중 단백질 프로파일링은 SARS-CoV-2 감염에 이차적으로 ARDS가 있는 중환자에서 질병, 사망률 및 호흡기 후유증과 관련된 징후를 나타냅니다.Multicenter Study Published on 2022-07-292022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome adverse outcomes AGR2 all-cause mortality ARDS association BAS bronchial bronchial aspirate confounding factors correlated COVID-19 COVID-19 patients Cox regression model Cox regression models Critically ill Critically ill patient critically ill patients CST5 Decision making determinant disease pathogenesis DPP7 ENTPD2 expressed Factor FCRL1 highest hospital discharge host response ICU ICU – intensive care unit identify IL-1α immune IMV intensive care Invasive mechanical ventilation Kaplan-Meier curve Kaplan-Meier curves KYAT1 lung cells Lung function mechanism molecular Mortality mortality risk multicenter study NADK Non-COVID-19 Non-COVID-19 patients nonsurvivor nonsurvivors NQO2 NTF4 OSM outcomes Pathogenesis pathology Poor Protein proteomic proteomics proteomics. proximity extension assay PTN quantified radiological feature radiological features random Random forest reduced respiratory respiratory distress Respiratory distress syndrome reveal risk Risk assessment SARS-COV-2 infection SRPK2 subgroup subgroups supported Survivors the disease the strongest THOP1 TRAIL TSS TYMP Viral viral infectivity were used with COVID-19 [DOI] 10.3389/fimmu.2022.942443 PMC 바로가기 [Article Type] Multicenter Study
Occupational safety of janitors in Ethiopian University during COVID-19 pandemic: Results from observational studyObservational Study Published on 2022-07-292022-10-04 Journal: Frontiers in Public Health [Category] 임상, [키워드] addition AOR conducted contribute COVID-19 COVID-19 infection COVID-19 transmission cross-sectional Ethiopia Ethiopian Factor Follow-up high risk identify independent involved janitor likelihood measure mechanisms multivariable logistic regression observation occupational occupational safety. Poor PPE Prevent previous study proportion protocol questionnaire Result significantly training university was used [DOI] 10.3389/fpubh.2022.895977 PMC 바로가기 [Article Type] Observational Study
COVID-19 Experiences and Health-Related Implications: Results From a Mixed-Method Longitudinal Study of Urban Poor Adolescents in ShanghaiResearch article Published on 2022-07-012022-10-05 Journal: The Journal of adolescent health : official public [Category] 진단, [키워드] Adolescent adolescent health Analysis analyzed Anxiety Boy change collected consequence COVID-19 COVID-19 impacts COVID-19 pandemic experience expressed Gender Gender inequality greater Health impacts implication improvement longitudinal mental health outcome pandemic Poor reported Result SARS-CoV-2 Sex Shanghai urban were assessed [DOI] 10.1016/j.jadohealth.2022.03.016 [Article Type] Research article
Usefulness of real-time RT-PCR to understand the kinetics of SARS-CoV-2 in blood: A prospective study혈액 내 SARS-CoV-2의 동역학 이해를 위한 실시간 RT-PCR의 유용성: 전향적 연구Observational Study Published on 2022-07-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Admission approved blood sample Blood samples Care case sery clinical Clinical outcome collected conducted death defined detection diagnosis of SARS-CoV-2 discharge expressed hospitalisation hospitalised COVID-19 patient hospitalised COVID-19 patients intensive care unit intensive care unit admission Kinetics median time Mortality occurred outcome Patient patients persistent plasma Plasma viral-load Poor progressed Prospective Study Quantitative Range real time real-time RT-PCR risk RT-PCR RT-PCR assay SARS-CoV-2 SARS-CoV-2 viral SARS-CoV-2 viral load serum sample serum samples significantly higher Viral load Viremia Viremia-kinetics. was determined [DOI] 10.1016/j.jcv.2022.105166 PMC 바로가기 [Article Type] Observational Study