Building-level wastewater surveillance of SARS-CoV-2 is associated with transmission and variant trends in a university settingArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant analyzed associations Building-level surveillance Clinical data clinical testing collected complement Concentration contributed COVID-19 COVID-19 case creating Epidemiology genetic mutation hotspot identify include indicate Intervention Isolation less log N1 and N2 Nucleocapsid gene positive positive control quantification quarantine repeated reported Research SARS-CoV-2 SARS-CoV-2 RNA second wave South spring statistical significance statistically significant Surveillance Transmission university variant variants of concern Viral RNA Viral transmission VOCs Wastewater-based epidemiology [DOI] 10.1016/j.envres.2022.114277 PMC 바로가기
Real-Time fast PCR amplification using designated and conventional real time thermal cycler systems: COVID-19 perspectiveArticle Published on 2022-10-202022-11-15 Journal: PLoS ONE [Category] 치료제, [키워드] ABI ABI 7500 Applied Biosystem approach Bio-rad comparable comparison Conventional COVID-19 COVID-19 sample detection did not produce Dilution human RP mRNA multiplex N1 and N2 optimization PCR PCR amplification Perspective positive control Precision protocol real time RNase P RT-PCR SARS CoV-2 sensitivity Sensitivity and specificity sequence specificity Standard System the median time touch was done was performed [DOI] 10.1371/journal.pone.0276464 PMC 바로가기
Decontamination of Geobacillus Stearothermophilus using the Arca Aerosolized Hydrogen Peroxide decontamination systemArticle Published on 2022-09-202022-11-16 Journal: PLoS ONE [Category] SARS, 임상, 치료기술, [키워드] Bacterial biologic caused clinical setting Concentration conducted Control decontamination effective Efficacy eight evaluate evaluated Greater than growth H2O2 hydrogen Indicator inoculated material Mesa negative control negative controls pandemic peroxide Personal protective equipment positive positive control PPM produced Respirator reuse SARS-CoV-2 sealed Seven System Trial trials [DOI] 10.1371/journal.pone.0273937 PMC 바로가기
(+)-Usnic acid and its salts, inhibitors of SARS-CoV-2, identified by using in silico methods and in vitro assay(+)-Usnic acid 및 그 염, SARS-CoV-2 억제제, in silico 방법 및 시험관 내 분석을 사용하여 확인Article Published on 2022-07-302022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] anti-SARS-CoV-2 Antiviral Beta variant beta variants calculated caused compounds continuum COVID-19 COVID-19 treatment database Efficacy immunofluorescence In silico method in vitro in vivo inhibitors inhibitors of SARS-CoV-2 investigated molecular molecular dynamics monoclonal antibodies Mpro protein pandemic positive control Protein target protein-ligand interaction Remdesivir required RMSD SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 variants selectivity index severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 sodium surface area targets Treatment treatment for COVID-19 usnic acid Virtual screening was performed was selected [DOI] 10.1038/s41598-022-17506-3 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 RNA throughout wastewater treatment plants and a modeling approach to understand COVID-19 infection dynamics in Winnipeg, Canada폐수 처리장 전체에서 SARS-CoV-2 RNA 검출 및 캐나다 위니펙의 COVID-19 감염 역학을 이해하기 위한 모델링 접근 방식Article Published on 2022-06-152022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] applied approach Back-trajectory modeling Canada Concentration Consensus correlation correlations COVID-19 infection Data analysis detection discharge Final fluctuation fluctuations fraction indicated infected individual Infection initial plant plants positive control processing reached reduction RNA RNA concentrations sample collection SARS-CoV-2 SARS-CoV-2 RNA sensitivity Sludge suggested supernatant Surveillance Treatment virus virus concentration wastewater Wastewater solids wastewater surveillance water water cycle Winnipeg [DOI] 10.1016/j.scitotenv.2022.153906 PMC 바로가기 [Article Type] Article
First computational design using lambda-superstrings and in vivo validation of SARS-CoV-2 vaccine Research Published on 2022-04-192022-10-05 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome Amino acid anti-viral response Asymptomatic Bacterial cellular coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patients cytokine profile dendritic cell disease Donor effective Efficacy effort elicit elicited epitope experiment Health Human humoral immune responses immune response Immunity in vivo indicated introduced negative control NTD NTD domain pathogen peptide peptide-based vaccine performed positive control predominant Protein provided Receptor binding domain Research SARS-CoV-2 SARS-CoV-2 vaccine subjects tested the Spike the vaccine Vaccine vaccine candidate Vaccines Validity volunteers [DOI] 10.1038/s41598-022-09615-w [Article Type] Research
Can periodontal pockets and caries lesions act as reservoirs for coronavirus?치주낭과 충치 병변이 코로나바이러스의 저장소 역할을 할 수 있습니까?Article Published on 2022-04-012022-09-11 Journal: Molecular oral microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplify approach Asymptomatic Can caries Chain Reaction coronavirus cross-sectional cross-sectional study Ct value detect dissemination evaluate Genes infections information knowledge lesion lesions negative control participant Patient patients periodontal pocket polymerase chain polymerase chain reaction positive positive control positive COVID-19 real-time polymerase chain reaction reservoir reservoirs RT-PCR S gene SARS-CoV-2 SARS-CoV-2 detection sensitivity severe acute respiratory syndrome Coronavirus specificity symptomatic the mean the SARS-CoV-2 virus while [DOI] 10.1111/omi.12362 PMC 바로가기 [Article Type] Article
Absence of SARS-CoV-2 Spike glycoprotein expression in placentas from individuals after mRNA SARS-CoV-2 vaccination Research Published on 2022-03-312022-10-05 Journal: Modern pathology : an official journal of the Unit [Category] SARS, 진단, [키워드] absence accumulate acute respiratory syndrome collected Concentration coronavirus current determine dose effort Evidence expression General population gestation global pandemic glycoprotein group Hesitancy immune cells immunohistochemistry include individual injection interval median interval MOST mRNA mRNA vaccine negative control negative controls observation occur paraffin-embedded Patient Placenta placental tissue Population positive positive control Pregnancy pregnant Protein protein translation provide public health receiving SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 vaccination SARS-CoV-2 vaccine spike spontaneous abortion the SARS-CoV-2 the study group translation vaccination vaccine dose was used [DOI] 10.1038/s41379-022-01061-3 [Article Type] Research
Antibody Responses to the BNT162b2 mRNA Vaccine in Healthcare Workers in a General Hospital in Japan: A Comparison of Two Assays for Anti-spike Protein Immunoglobulin G일본 종합병원 의료 종사자의 BNT162b2 mRNA 백신에 대한 항체 반응: 안티스파이크 단백질 면역글로불린 G에 대한 두 가지 분석 비교Article Published on 2022-03-152022-09-12 Journal: Internal medicine (Tokyo, Japan) [Category] MERS, SARS, 진단, [키워드] Abbott Accuracy acute respiratory syndrome anti-SARS-CoV-2 antibody Anti-spike anti-spike protein immunoglobulin G Antibody Response Antibody titer Blood BNT162b2 mRNA BNT162b2 mRNA vaccine collected Complete confidence interval coronavirus coronavirus disease Coronavirus disease 2019 correlation coefficient diagnostic dose effective first vaccination Fujirebio healthcare healthcare worker immunoassays Immunoglobulin Immunoglobulin G immunosuppressive drugs indicated individual infected with SARS-CoV-2 interquartile Japanese Linear regression analysis median medication Neutralizing neutralizing antibody objective participant participated Patient Pearson positive control Prevalence prospective cohort study Protein provided reference test response Result SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 significantly vaccination Vaccine was measured worker [DOI] 10.2169/internalmedicine.8704-21 PMC 바로가기 [Article Type] Article
Capability of novel fluorescence DNA-conjugated CdTe/ZnS quantum dots nanoprobe for COVID-19 sensingCOVID-19 감지를 위한 새로운 형광 DNA 접합 CdTe/ZnS 양자점 나노프로브의 기능Article Published on 2022-03-152022-09-11 Journal: Spectrochimica acta. Part A, Molecular and biomole [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] CdTe/ZnS quantum dots complementary Complementary DNA Concentration conditions conjugate COVID-19 Covide-19 virus DNA energy transfer fluorescence intensity FRET infected patient infected patients linear linear equation mixture Nanosensor Nanosensor. outcome positive control R 2 Regression replacing RNA RT-PCR Saliva thioglycolic acid was determined [DOI] 10.1016/j.saa.2021.120702 PMC 바로가기 [Article Type] Article