Spectral and theoretical study of SARS-CoV-2 ORF10 protein interaction with endogenous and exogenous macroheterocyclic compoundsSARS-CoV-2 ORF10 단백질과 내인성 및 외인성 거대 이종고리 화합물 상호작용에 대한 스펙트럼 및 이론 연구Article Published on 2022-10-152022-09-11 Journal: Spectrochimica acta. Part A, Molecular and biomole [Category] COVID19(2023년), SARS, 치료제, [키워드] Accessory accessory protein accessory proteins Alpha Antiviral approved bind carried caused cells Chlorin choice complexes Complexes Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria drug effective drug effective drugs energy Escherichia coli expressed Features form health problem highest affinity Host immune response in silico infected patient infected patients inhibitor inhibitory initial Interaction macrocycle matter modulate molecular docking MOST ORF10 ORF10 protein Orientation pandemic Pathogenesis Porphyrin Pragmatic precedence Protein protoporphyrin public health recommendation resource SARS-CoV-2 SARS-CoV-2 accessory proteins SARS-CoV-2 coronavirus silico studies Spectral Spectroscopy Spectroscopy. Spread Stage suggested Taking the disease the SARS-CoV-2 Treatment treatment of COVID-19 virucidal virus [DOI] 10.1016/j.saa.2022.121403 PMC 바로가기 [Article Type] Article
The impact of COVID-19 restrictions on participant enrollment in the PREPARE trialResearch article Published on 2022-10-012022-10-05 Journal: Contemporary Clinical Trials Communications [Category] 임상, [키워드] affected approval clinical trials COVID-19 COVID-19 pandemic COVID-19 research Enrollment Evaluating extremities implementation interquartile range median pandemic participant Patient Pragmatic pragmatic trials PREPARE trial protocol recorded researcher Result significantly lower skin solution t-test Trial [DOI] 10.1016/j.conctc.2022.100973 [Article Type] Research article
Safety, immunogenicity, and immune persistence of two inactivated COVID-19 vaccines replacement vaccination in China: An observational cohort studyArticle Published on 2022-09-162022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] administration Adverse reaction All participant anti-SARS-CoV-2 approved BBIBP-CorV can be used China Complete control group COVID-19 COVID-19 vaccine Cytopathic effect dose doses first dose geometric mean concentration geometric mean titer GMCs GMTs healthy immune persistence immunogenicity Immunoglobulin inactivated Inactivated vaccine Mild mitigate moderate NAb National not different not significantly different observation Observational cohort study Pragmatic regimens replacement Replacement vaccine Safety safety profile Safety. SARS-CoV-2 strain second dose sera severity Standard subject vaccination WHO [DOI] 10.1016/j.vaccine.2022.08.037 PMC 바로가기
Diaphragm ultrasound evaluation during weaning from mechanical ventilation in COVID-19 patients: a pragmatic, cross-section, multicenter studyCOVID-19 환자의 기계 환기에서 이유 중 횡격막 초음파 평가: 실용적, 횡단면, 다기관 연구Observational Study Published on 2022-08-212022-09-12 Journal: Respiratory Research [Category] 임상, 진단, [키워드] Clinical practice correlated COVID-19 COVID-19 patient Diaphragm diaphragmatic dysfunction enrolled evaluate fraction generalized linear regression hospital ICU information intensive care intensive care units Invasive mechanical ventilation invasive ventilation IQR Italian Mechanical mechanical ventilation multicenter oxygen PaO Patient Pragmatic predict Predictive responsible severe respiratory failure Trial Ultrasound variable weaning Weaning failure. [DOI] 10.1186/s12931-022-02138-y PMC 바로가기 [Article Type] Observational Study
Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise-CISCO-21Randomized Controlled Trial Published on 2022-08-152022-10-05 Journal: Trials [Category] SARS, 임상, [키워드] Admission breathlessness cause chest pain Contact Controlled clinical trial COVID COVID-19 COVID-19 infection diagnosis of COVID-19 discharged Dyspnoea early treatment Effect Ethical approval ethics committee Exercise capacity fatigue frailty group Health Health status healthcare professionals hospital hospitalisation hospitalised Infection Intervention Long Long COVID National Health Service NHS participant Patient personalised physical physical activity Pragmatic prevention Primary outcome problem Quality of life questionnaire randomisation randomised randomised controlled trial REC recruitment Registered rehabilitation resistance resistance exercise SARS-CoV-2 SARS-CoV-2. secondary outcome spirometry Symptom syndrome therapy Two-arm usual care West [DOI] 10.1186/s13063-022-06632-y PMC 바로가기 [Article Type] Randomized Controlled Trial
A pragmatic randomized trial of home-based testing for COVID-19 in rural Native American and Latino communities: Protocol for the “Protecting our Communities” studyArticle Published on 2022-08-012022-10-05 Journal: Contemporary clinical trials [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] added American Arm ARMS benefit Care Community community health Community health worker Community trial conducted COVID-19 COVID-19 test COVID-19 testing economic barrier evaluate feasibility Health health worker Home-based testing implementation Implementing lab Laboratory Latino nasal swab Native Native American outcome participant Population populations Pragmatic Protecting Randomized Randomized controlled trial randomized trial receive reduce Research SARS-CoV-2 SARS-CoV-2. Support The United States Trial Two-arm Washington [DOI] 10.1016/j.cct.2022.106820 PMC 바로가기 [Article Type] Article
Post-Acute COVID-19 Syndrome for Anesthesiologists: A Narrative Review and a Pragmatic Approach to Clinical CareReview article Published on 2022-08-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] SARS, 임상, [키워드] acute infection anticoagulation avoidance blocking agent Brain chest pain clinical clinical care Clinical practice Cognitive impairment consequence coronavirus disease Course COVID-19 criterion Critical care determine Dyspnea Evidence fatigue Health healthy higher risk include Infection initial Long COVID lung-protective ventilation medication Mental Mortality Myopathy narrative nonspecific pandemic Patient patients performed Perioperative care perioperative considerations persistence physical Post-acute COVID-19 syndrome post-viral syndrome postoperative Pragmatic preoperative evaluation Pulmonary pathology regimen respiratory complication review Seven syndrome the United State [DOI] 10.1053/j.jvca.2021.09.051 [Article Type] Review article
Network methods and design of randomized trials: Application to investigation of COVID-19 vaccination boosters네트워크 방법 및 무작위 시험 설계: 코로나19 백신 부스터 조사에 적용Article Published on 2022-08-012022-09-11 Journal: Clinical Trials (London, England) [Category] COVID19(2023년), SARS, 변종, 임상, 치료기술, 치료제, [키워드] Analysis antibody tests application approach approval arise booster Booster vaccine booster vaccines can be used Characteristics Clinical efficacy Cluster Combination consequence Contact COVID-19 COVID-19 vaccination detectability disease Effect Efficacy enrolled error evaluate the effect Evidence evidence of feasible flexible framework Guidance HIV HIV prevention incidence Infection infections infectiousness information intervention effect Intervention effects magnitude Molecular epidemiology motivation network network science. neutralizing antibody novel populations Pragmatic provide random Randomized randomized trial randomized trials reduce cost Sample size SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variants Spread Standard of care statistical Study design susceptibility Transmission Trial United Kingdom Vaccine vaccine efficacy variant [DOI] 10.1177/17407745221111818 PMC 바로가기 [Article Type] Article
Lead time of early warning by wastewater surveillance for COVID-19: Geographical variations and impacting factorsReview article Published on 2022-08-012022-10-05 Journal: Chemical Engineering Journal [Category] 바이오마커, [키워드] affected approach article climatic zone comparability comparable Concentration condition correlation country COVID-19 COVID-19 case Degradation epidemiological evaluated Factor feature generate Genome knowledge Lead time Pragmatic reported RNA SARS-CoV-2 SARS-CoV-2 RNA seasonality sensitivity significantly Surveillance Temporal and spatial variation Variation Viral RNA virus WASH WBE [DOI] 10.1016/j.cej.2022.135936 [Article Type] Review article
Preliminary Approach to Implementing a COVID-19 Thoracic Radiation Therapy ProgramResearch article Published on 2022-07-012022-10-05 Journal: Practical Radiation Oncology [Category] COVID19(2023년), SARS, 임상, [키워드] administration clinical trial Community COVID-19 effective hospital implementation Implementing low-dose patients with COVID-19 Pneumonia Pragmatic Program radiation therapy Safe SARS-CoV-2 Thoracic widespread [DOI] 10.1016/j.prro.2021.12.014 [Article Type] Research article