Presymptomatic viral shedding in high-risk mpox contacts: A prospective cohort studyArticle Published on 2023-05-012023-06-10 Journal: Journal of medical virology [Category] 원숭이두창, [키워드] Monkeypox virus mpox presymptomatic Transmission viral shedding [DOI] 10.1002/jmv.28769
Transmission of SARS-CoV-2 from pre and asymptomatic infected individuals: a systematic review updateArticle Published on 2022-11-012023-07-09 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), [키워드] Asymptomatic presymptomatic SARS-CoV-2 Systemic review update Transmission [DOI] 10.1016/j.cmi.2022.06.016 PMC 바로가기
Immunological and Pathological Peculiarity of Severe Acute Respiratory Syndrome Coronavirus 2 Beta VariantArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, [키워드] Activation acute respiratory syndrome Analysis Beta Beta variant blockade cascade cause CCL2 Characteristics Comparative analysis coronavirus coronavirus 2 COVID-19 COVID-19 pandemic CXCR2 cytokine cytokine release death Disease progression early stage evidenced IL-1β immunological induce Infection Inflammatory cytokine investigated K18-hACE2 late stage Lung pathology mice molecular mechanism Mortality neutrophil recruitment outbreak pathological pathological condition pathology phenotype presymptomatic provide reduced respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis SARS-CoV-2 variant secreted cytokine Strains the SARS-CoV-2 Transcriptome transcriptomes Transmissibility Treatment variant viral infection weight loss [DOI] 10.1128/spectrum.02371-22 PMC 바로가기
The Variation of Transcriptomic Perturbations is Associated with the Development and Progression of Various DiseasesArticle Published on 2022-09-262022-11-16 Journal: Disease Markers [Category] 유전자 메커니즘, [키워드] activities AIDS AIDS patient Algorithm analyzed applied association atrophic gastritis cardiovascular diseases caused cellular chronic obstructive clinical implication clinically controls COPD correlated correlation COVID-19 patient deficiency defined development digestive disease Disease diagnosis Disease progression Diseases Ejection fraction Endocrine diseases expiratory expression greater Health status heterogeneity ICU immune Infection intensive care investigated involved Kidney diseases liver diseases LVEF malaria mechanical ventilatory support negative correlation Neurological disorders non-ICU patients pathway patients Perturbation presymptomatic Prognosis pulmonary disease pulmonary tuberculosis Regulation respiratory diseases severity significantly syndrome the disease Therapies transcriptome datasets transcriptomic transcriptomic data treated upregulated upregulation Variation variety ventricular Viral load Volume [DOI] 10.1155/2022/2148627 PMC 바로가기
Symptomatic, Presymptomatic, and Asymptomatic Transmission of SARS-CoV-2 in a University Student Population, August-November 20202020년 8월-11월 대학생 인구에서 SARS-CoV-2의 증상, 전증상 및 무증상 전파Article Published on 2022-09-012022-09-11 Journal: Public health reports (Washington, D.C. : 1974) [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI addition Analysis association Asymptomatic asymptomatic transmission attack rate close contact Cohort Community Contact tracing COVID-19 COVID-19 infection COVID-19 test Dame determine Fisher exact test Fisher exact tests guide Health help Host index case index cases infectious Population presymptomatic presymptomatic case Presymptomatic cases presymptomatic index case presymptomatic index cases producing public health measure question Relative risk risk SAME AS SAR SARS SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2 variant SARS-CoV-2 variants secondary attack rate Spread spread of COVID-19 statistical difference statistical differences student Symptom symptomatic symptomatic case symptomatic cases symptomatic index cases Transmission transmission of SARS-CoV-2 transmission rate transmission rates university variant [DOI] 10.1177/00333549221110300 PMC 바로가기 [Article Type] Article
Frequent detection but lack of infectivity of SARS-CoV-2 RNA in presymptomatic, infected blood donor plasmaArticle Published on 2022-09-012022-11-15 Journal: The Journal of Clinical Investigation [Category] SARS, 치료기술, [키워드] Blood blood donor cell line clinical Clinical practice cough COVID-19 COVID-19 mortality COVID-19 patient detectable detection Diagnosis diagnosis of COVID-19 Donor General population implementation Infectious virus Influenza information lack less Limits of detection mice Mild Molecular diagnosis Pathogenesis PDI peaked plaque-forming unit plasma presymptomatic produced question raise reported respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA severe symptoms Shortness of breath susceptible Symptom tested unlikely vaccination virus widespread [DOI] 10.1172/JCI159876 PMC 바로가기
PCovNet: A presymptomatic COVID-19 detection framework using deep learning model using wearables dataPCovNet: 웨어러블 데이터를 사용하는 딥 러닝 모델을 사용하는 전증상 COVID-19 감지 프레임워크Article Published on 2022-08-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, [키워드] abnormality Achille Administered Anomaly anomaly detection autoencoder average Chain Reaction circumvent contagious COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 pandemic dataset deep learning detect Diagnosis diagnostic evaluated feasibility framework healthcare heart heart rate individual Long Long short-term memory management protocol presymptomatic provoke Rate recall resting Resting heart rate Reverse transcription-polymerase chain reaction RT-PCR Secondary diagnosis Short-Term Memory smartwatch span Spread subject Symptom symptom onset Transmission Variational autoencoder. viral pathogen while [DOI] 10.1016/j.compbiomed.2022.105682 PMC 바로가기 [Article Type] Article
Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective cohort study (COVI-GAPP)COVID-19와 관련된 생리적 매개변수의 변화를 무증상으로 감지하기 위한 센서 팔찌의 사용 조사: 전향적 코호트 연구(COVI-GAPP)의 중간 분석Randomized Controlled Trial Published on 2022-06-212022-09-11 Journal: BMJ Open [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료기술, [키워드] age Algorithm Analysis baseline changes in cohort study COVID-19 diagnosed FIVE health & health informatics heart rate HRV Incubation infection control Interim interim analysis investigated investigation memory molecular National parameter participant Participants physiological Physiology positive presymptomatic prospective cohort study Public public health random randomised recall Recurrent Neural Network registration number respiratory rate Safety SARS-COV-2 infection selected sensitivity serological assays setting Short-Term Memory significant changes in symptom onset symptomatic temperature training set Trial Variability Virology were recorded [DOI] 10.1136/bmjopen-2021-058274 PMC 바로가기 [Article Type] Randomized Controlled Trial
Onasemnogene abeparvovec for presymptomatic infants with three copies of SMN2 at risk for spinal muscular atrophy: the Phase III SPR1NT trial Research Published on 2022-06-172022-10-05 Journal: Nature Medicine [Category] 변종, 유전자 메커니즘, 임상, 진단, [키워드] biallelic children Deletion develop developmental effective Efficacy and safety Infant Intervention investigated investigator MOST multicenter muscular Mutation phase presymptomatic required Respiratory Support risk Serious Adverse Event single-arm trial SMN1 SMN2 Support survived symptom onset treated Trial urgency Ventilation WHO [DOI] 10.1038/s41591-022-01867-3 [Article Type] Research
Onasemnogene abeparvovec for presymptomatic infants with two copies of SMN2 at risk for spinal muscular atrophy type 1: the Phase III SPR1NT trial Research Published on 2022-06-172022-10-05 Journal: Nature Medicine [Category] 변종, 유전자 메커니즘, 임상, [키워드] biallelic children Clinical research Cohort develop developmental effective Efficacy and safety enrolled expected Final highlighting Infant investigator multicenter muscular Mutation Neuromuscular Newborn phase presymptomatic Respiratory Support risk Serious Adverse Event single-arm study SMN1 SMN2 survived treated Treatment Trial urgency Ventilation WHO [DOI] 10.1038/s41591-022-01866-4 [Article Type] Research