Broad-Spectrum Extracellular Antiviral Properties of Cucurbit[ n]urilsArticle Published on 2022-10-142022-11-15 Journal: ACS Infectious Diseases [Category] COVID19(2023년), SARS, 치료제, [키워드] acting amino acids Antiviral Antiviral compound Antiviral effect antivirals Cell Compound compounds Contact cucurbituril disease dose−response Efficacy Extracellular herpes simplex homologue Interaction investigated macrocycle mechanism morbidity Mortality nontoxic pathogen property Protein respiratory syncytial virus responsible RSV SARS-CoV-2 viral surface virucidal virus viruses virustatic. [DOI] 10.1021/acsinfecdis.2c00186 PMC 바로가기
Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particlesOmicron 돌연변이는 SARS-CoV-2 바이러스 유사 입자의 감염성을 높이고 항체 중화를 감소시킵니다.Article Published on 2022-08-022022-09-11 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Antibody neutralization Antisera assembly B.1 B.1 lineage B.1.1 bebtelovimab Casirivimab Cell cell entry change convalescent sera coronavirus COVID-19 Delta detectable detrimental dose Effect Efficacy Efficiency eight eight subject elicited ENhance examined Imdevimab individual Johnson & Johnson Johnson & Johnson luciferase Moderna monoclonal antibodies monoclonal antibody Mutation N proteins neutralization neutralization activity neutralization titer Neutralizing antibodies neutralizing antibody omicron Omicron variant Patient Pfizer Pfizer/BioNTech Prevent property reduce reduced respiratory resulting robust SARS-CoV-2 SARS-CoV-2 variant sequence sera severe acute respiratory syndrome Coronavirus Spike protein Spread structural protein structural proteins subjects survivor Vaccine Vaccines variant variants Viral viral infectivity Virus-like particle virus-like particles VLP VLPs [DOI] 10.1073/pnas.2200592119 PMC 바로가기 [Article Type] Article
Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other LineagesCOVID-19 환자의 비인두 샘플에서 SARS-CoV-2 분석은 다른 계통과 관련하여 우려되는 변이체의 성장 특성을 배치하여 인구 변이 및 다양한 표현형을 보여줍니다Article Published on 2022-06-292022-09-11 Journal: mSphere [Category] COVID19(2023년), SARS, 변종, [키워드] A549 cells Alpha amplified Beta Beta variant Biology biology of SARS-CoV-2 causative agent Cell Cell culture cell line cells change characterized clinical isolates clinical samples concern Context coronavirus COVID-19 Delta disease effective Evolution genetic diversity genetics genome sequence genomic global pandemic growth growth kinetics hACE2 hospitalized patient hospitalized patients humans immune evasion increased risk indicated Infection isolate isolates less Lineage minor minor genomic variants morbidity Mortality Nasopharyngeal swab nasopharyngeal swabs New no difference not different omicron Other other coronaviruses other variant other variants pandemic patients pattern planet Population Population dynamics Population genetics Postinfection preserved property Research RNA RNA sequencing Sample SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes sequence several variants Spread suggested Transmission vaccination Vaccine Variability variant variants variants of concern variants of SARS-CoV-2 Variation Vero E6 Vero E6 cell VERO E6 cells virus Virus evolution VoC VOCs widespread with COVID-19 [DOI] 10.1128/msphere.00913-21 PMC 바로가기 [Article Type] Article
Virucidal Properties of Photocatalytic Coating on Glass against a Model Human Coronavirus모델 인간 코로나바이러스에 대한 유리의 광촉매 코팅의 바이러스 살균 특성Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료제, [키워드] added aerosol alteration Antiviral antiviral activity can not coated with coating construction Contact Contagion Contamination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 damaged deformation Disruption electron microscopy element Epidemiology Evidence evidence of exposure to glass human coronavirus human coronaviruses in-depth analysis inactivation increase infectious investigated Kinetics knowledge Masks Microscopy mitigate Model morphologically pandemic performed Photocatalysis photocatalytic coating physical physical barrier property Protective protective effect Protective effects reduced reducing Research SARS-CoV-2 Spread suggested surface titanium titanium dioxide Transmission viral envelope virion virions virucidal virucidal activity virus virus spread virus titer viruses [DOI] 10.1128/spectrum.00269-22 PMC 바로가기 [Article Type] Article
Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529신흥 SARS-CoV-2 변이체 B.1.1.529의 스파이크 당단백질의 기능적 특성Article Published on 2022-06-142022-09-11 Journal: Cell Reports [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 affinity ACE2 binding acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 B.1.1.529 B.1.617.2 Cell coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CP: Immunology CP: Microbiology cytopathic effects D614G decrease exhibit functional glycoprotein higher affinity immune evasion immunology Infection less Microbiology neutralization neutralization sensitivity omicron Patient prevalent processing property pseudovirus pseudoviruses relative S glycoprotein S glycoproteins S trimer S1 shedding SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sera severe acute respiratory syndrome Coronavirus spike glycoprotein stability syncytium formation temperature TMPRSS2 TMPRSS2 expression Transmission unliganded vaccinees variant variants virion [DOI] 10.1016/j.celrep.2022.110924 PMC 바로가기 [Article Type] Article
Synthesis and Antiviral Properties against SARS-CoV-2 of Epoxybenzooxocino[4,3- b]Pyridine DerivativesEpoxybenzooxocino[4,3-b]Pyridine 유도체의 SARS-CoV-2에 대한 합성 및 항바이러스 특성Article Published on 2022-06-092022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 치료제, [키워드] Antiviral antiviral activity approved drug cell cultures clinically comparable compounds COVID-19 pandemic demonstrated derivative derivatives described drugs epoxybenzooxocinopyridine derivatives. half-maximal effective concentration inhibit property Replication SARS-CoV-2 SARS-CoV-2 virus Seven suppress synthesis tested the SARS-CoV-2 virus therapeutic [DOI] 10.3390/molecules27123701 PMC 바로가기 [Article Type] Article
GEOM, energy-annotated molecular conformations for property prediction and molecular generation Research Published on 2022-04-212022-10-05 Journal: Scientific Data [Category] 치료제, [키워드] 3D structure approach assist conformation conformations dataset functional generate machine ML model molecular molecule outperform physical predict property solvent [DOI] 10.1038/s41597-022-01288-4 [Article Type] Research
Properties of the Omicron Variant of SARS-CoV-2 Affect Public Health Measure Effectiveness in the COVID-19 EpidemicSARS-CoV-2의 오미크론 변종 특성이 COVID-19 전염병에서 공중 보건 측정 효과에 영향을 미침Article Published on 2022-04-192022-09-11 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adaptation change changes in characteristic Characteristics Cluster Contact Containment coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 decrease diminishe Effect Effectiveness Epidemic epidemiological Generation time increase infected children Intervention investigated Isolation Japan measure mitigate nonpharmaceutical intervention omicron Omicron variant property Public public health Public health intervention Public health interventions public health measure public health measures reduction required SARS-CoV-2 severe acute respiratory syndrome Coronavirus vaccination variant variants viral evolution [DOI] 10.3390/ijerph19094930 PMC 바로가기 [Article Type] Article
The Antioxidant, Anti-Platelet and Anti-Coagulant Properties of Phenolic Compounds, Associated with Modulation of Hemostasis and Cardiovascular Disease, and Their Possible Effect on COVID-19지혈 및 심혈관 질환의 조절과 관련된 페놀 화합물의 항산화, 항혈소판 및 항응고 특성 및 COVID-19에 대한 가능한 영향Review Published on 2022-03-262022-09-11 Journal: Nutrients [Category] 치료제, [키워드] affected animals Anticoagulant antioxidant antiviral activities antiviral activity Antiviral effect antiviral effects benefit blood platelet can not cardiovascular cardiovascular disease cause of death changes in coagulation dysfunction Complication Compound compounds coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection Curcumin CVD death Effect Efficiency Evidence Hemostasis Human implication in vitro in vivo less modulation myricetin offer oxidative stress patients with COVID-19 Phenolic compounds Platelet positive Prevent property Prophylactic Prophylaxis recommendation reduce resveratrol risk selected suggested Treatment treatment of COVID-19 while with COVID-19 [DOI] 10.3390/nu14071390 PMC 바로가기 [Article Type] Review
Preclinical Studies on Convalescent Human Immune Plasma-Derived Exosome: Omics and Antiviral Properties to SARS-CoV-2회복기 인간 면역 혈장 유래 엑소좀에 대한 전임상 연구: SARS-CoV-2에 대한 오믹스 및 항바이러스 특성Article Published on 2022-03-242022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료제, [키워드] biochemical convalescence plasma convalescent convalescent plasma COVID-19 COVID-19 pandemic Efficacy Exosome Exosomes Extracellular extracellular vehicles (EVs) Extracellular vesicles Gene ontology Good good manufacturing practice Human immune measure Ministry of Health passive immunity Practice Preclinical property SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Society Support Treatment Turkish Red Crescent Viral viral treatment. [DOI] 10.3389/fimmu.2022.824378 PMC 바로가기 [Article Type] Article