Computational Modelling, Functional Characterization and Molecular Docking to Lead Compounds of Bordetella pertussis Diaminopimelate Epimerasearticle Published on 2023-11-302024-09-01 Journal: Applied Biochemistry and Biotechnology [Category] 백일해, [키워드] Diaminopimelate epimerase docking Protein interaction network Structural analysis [Article Type] article
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein ComplexesOriginal Research Published on 2023-09-182024-09-05 Journal: Genomics, Proteomics & Bioinformatics [Category] update2024, [키워드] Complex identification method Human protein complex multifunctional protein Protein interaction network SARS-CoV-2-affected complex [DOI] 10.1016/j.gpb.2023.05.001 PMC 바로가기 [Article Type] Original Research
A scheme for inferring viral-host associations based on codon usage patterns identifies the most affected signaling pathways during COVID-19코돈 사용 패턴을 기반으로 바이러스 숙주 연관을 추론하는 체계는 COVID-19 동안 가장 영향을 받는 신호 경로를 식별합니다Article Published on 2021-06-012022-09-11 Journal: Journal of biomedical informatics [Category] 신약개발, 유전자 메커니즘, [키워드] affected Analysis arsenic Arsenic trioxide association Bipartite graph Cell signaling centrality clinical trial codon codon usage Codon usage bias Codons correlated COVID-19 COVID-19 pathogenesis Dexamethasone disease pathogenesis drugs expression help Host host protein host proteins Hydroxychloroquine identify Infection Interaction interferon beta MAPK mechanism molecular mechanism multiple pathway multiple pathways network non-structural proteins Nsp3 observé organized pair Pathogenesis pathway Pathways performed PPI PPI network Protein Protein interaction network protein-protein interaction recent relative Relative synonymous codon usage. reveal Ritonavir SARS-COV-2 infection SARS-CoV-2 proteins signaling pathway similarity spike structural protein synonymous target the SARS-CoV-2 therapeutic target translational trioxide understanding Viral protein Viral proteins while [DOI] 10.1016/j.jbi.2021.103801 PMC 바로가기 [Article Type] Article
Deciphering underlying mechanism of Sars-CoV-2 infection in humans and revealing the therapeutic potential of bioactive constituents from Nigella sativa to combat COVID19: in-silico studyResearch Article Published on 2020-10-282023-07-02 Journal: Journal of biomolecular structure & dynamics [Category] COVID19(2023년), SARS, [키워드] α-hederin Angiotensin-II receptor (ACE2) Nigella Sativa Protein interaction network SARS-CoV-2 [DOI] 10.1080/07391102.2020.1839560 PMC 바로가기 [Article Type] Research Article
Investigating the human protein-host protein interactome of SARS-CoV-2 infection in the small intestineOriginal Article Published on 2020-01-012022-10-31 Journal: Gastroenterology and Hepatology From Bed to Bench [Category] COVID-19, [키워드] ACE2 Antiviral association biological processes Biomarker categories COVID-19 patients database digestion disease DPP4 drug candidate drug targets drug-target interaction element expression functional Gastrointestinal symptom HNF1A HNF1B HNF4A host protein identify IMPROVE Infection Inflammation Interaction interactome investigated mechanism mechanisms MEP1A MEP1B Ontology organ pathway Pathways potential mechanism PPI Protein protein interaction Protein interaction network protein-protein interaction Public receptor ACE2 Regulatory regulatory network SARS-CoV-2 SARS-COV-2 infection small intestine the SARS-CoV-2 therapeutic target tissue transcription factor transcription factors Treatment strategies were used XPNPEP2 PMC 바로가기 [Article Type] Original Article