Accessing isotopically labeled proteins containing genetically encoded phosphoserine for NMR with optimized expression conditionsArticle Published on 2022-12-012023-07-10 Journal: The Journal of Biological Chemistry [Category] COVID19(2023년), [키워드] genetic code expansion nuclear magnetic resonance phosphoserine post-translation modification protein expression protein phosphorylation protein synthesis. [DOI] 10.1016/j.jbc.2022.102613 PMC 바로가기
Porcine deltacoronavirus E protein induces interleukin-8 production via NF-κB and AP-1 activationArticle Published on 2022-11-012022-11-15 Journal: Veterinary microbiology [Category] SARS, 유전자 메커니즘, 치료제, [키워드] abrogated activated activating Activation acute respiratory syndrome Alpha antiviral immunity AP-1 binding C-terminal domain caused chemokine coronavirus coronavirus disease COVID-19 Cytokine release syndrome deleting demonstrated dependent on domain E E protein expression facilitate help IL-6 IL-8 induce Infection Inflammation inhibitor interleukin-6 IκBα life-threatening Local molecular mechanism motif NF-κB NF-κB pathway nuclear nuclear translocation p65 Pathogenesis PDCoV. Phosphorylation Proinflammatory cytokine promoter protein phosphorylation resulting SARS-CoV-2 Severe case upregulated [DOI] 10.1016/j.vetmic.2022.109553 PMC 바로가기
Phosphorylation of Influenza A Virus NS1 at Serine 205 Mediates Its Viral Polymerase-Enhancing FunctionArticle Published on 2021-02-242023-06-14 Journal: Journal of Virology [Category] Fulltext, 신종인플루엔자, [키워드] Influenza virus NS1 protein phosphorylation viral polymerase activity. [DOI] 10.1128/JVI.02369-20 PMC 바로가기
Site-Specific Mutations of GalR Affect Galactose Metabolism in Streptococcus pneumoniae갈R의 위치 특이적 돌연변이가 폐렴구균의 갈락토오스 대사에 영향을 미친다.Article Published on 2020-12-072024-08-24 Journal: Retinal cases & brief reports [Category] 폐렴구균 감염증, [키워드] carbon metabolism galactose GalR pneumococcus protein phosphorylation Streptococcus pneumoniae virulence
Phosphorylation of Rhoptry Protein RhopH3 Is Critical for Host Cell Invasion by the Malaria Parasite말라리아 기생충의 숙주 세포 침입에 있어 Rhoptry 단백질 RhopH3의 인산화는 중요하다.Research Article Published on 2020-10-062024-08-11 Journal: mBio [Category] 말라리아, [키워드] host cell invasion Invasion malaria Phosphorylation protein phosphorylation Signaling [DOI] 10.1128/mBio.00166-20 PMC 바로가기 [Article Type] Research Article
A new identified suppressor of Cdc7p/SepH kinase, PomA, regulates fungal asexual reproduction via affecting phosphorylation of MAPK-HogACdc7p/SepH 키나아제의 새로 확인된 억제제인 PomA는 MAPK-HogA의 인산화에 영향을 주어 진균 무성 생식을 조절합니다Research Article Published on 2019-06-132022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] absence Affect affecting asexual asexual reproduction Author bypass bypassing cascade Cell composed conidiation conserved Crosstalk cytokinesis environmental factors environmental niche event finding fungal fungi glycerol indicated kinases MAPK mitogen mitogen-activated protein kinase mutant nidulan nidulans osmotic overexpression pathway Pathways phosphorylated Phosphorylation Protein protein kinase protein phosphorylation regulate regulated required respond septation Signaling Stress suppresse suppressor tyrosine upstream [DOI] 10.1371/journal.pgen.1008206 PMC 바로가기 [Article Type] Research Article
Calcium-dependent phosphorylation of Plasmodium falciparum serine repeat antigen 5 triggers merozoite egressArticle Published on 2018-06-222024-08-28 Journal: Brain stimulation [Category] 말라리아, [키워드] CDPK1 malaria merozoites egress Phosphoproteomics Plasmodium Plasmodium falciparum posttranslational modification (PTM) protein phosphorylation SERA5
Hepatitis B Virus Core Protein Dephosphorylation Occurs during Pregenomic RNA EncapsidationArticle Published on 2018-06-132023-06-16 Journal: Journal of Virology [Category] B형 간염, Fulltext, [키워드] Antiviral agents capsid assembly capsid assembly modulators Hepatitis B virus protein phosphorylation viral replication [DOI] 10.1128/JVI.02139-17 PMC 바로가기
MoCAP proteins regulated by MoArk1-mediated phosphorylation coordinate endocytosis and actin dynamics to govern development and virulence of Magnaporthe oryzaeMoArk1 매개 인산화에 의해 조절되는 MoCAP 단백질은 세포내이입과 액틴 역학을 조정하여 Magnaporthe oryzae의 발병 및 독성을 제어합니다Research Article Published on 2017-05-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin addition Analysis Author cellular conidia conidiation connection conserved Deletion endocytosis eukaryotic cells Evidence exhibited F-actin function functions fungi growth homolog host cells host infection hyphal in vivo invasive lead Magnaporthe mechanism modulate mutant mutants mycelial participated pathogenic pathogenicity penetration phosphatidylinositol phospholipid Phosphorylation PIP previous study Protein protein phosphorylation provided reduced regulate regulated Regulation required residue Signaling subject subunit type strain virulence wild-type strain [DOI] 10.1371/journal.pgen.1006814 PMC 바로가기 [Article Type] Research Article
Rewiring the Pneumococcal Cell Cycle with Serine/Threonine- and Tyrosine-kinases세린/트레오닌 및 티로신 키나제로 폐렴구균 세포 주기 재배선journal-article Published on 2016-09-012024-08-01 Journal: Trends in Microbiology [Category] 폐렴구균 감염증, [키워드] bacterial cell cycle cell division cell morphogenesis polysaccharide capsule biosynthesis and export protein phosphorylation Streptococcus pneumoniae [DOI] 10.1016/j.tim.2016.04.004 [Article Type] journal-article