The Evaluation of Drugs as Potential Modulators of the Trafficking and Maturation of ACE2, the SARS-CoV-2 ReceptorArticle Published on 2024-06-272024-09-05 Journal: Biomolecules [Category] update2024, [키워드] ACE2 Cellular localization COVID-19 drugs screening molecular modulators of transportation protein trafficking [DOI] 10.3390/biom14070764 PMC 바로가기 [Article Type] Article
Glycosylation Modulation Dictates Trafficking and Interaction of SARS-CoV-2 S1 Subunit and ACE2 in Intestinal Epithelial Caco-2 CellsArticle Published on 2024-04-302024-09-05 Journal: Biomolecules [Category] update2024, [키워드] glycosylation N-butyldeoxynojirimycin protein trafficking Protein–protein interaction SARS-CoV-2 [DOI] 10.3390/biom14050537 PMC 바로가기 [Article Type] Article
Lipid rafts disruption by statins negatively impacts the interaction between SARS-CoV-2 S1 subunit and ACE2 in intestinal epithelial cellsMicrobiology Original Research Published on 2024-01-082024-09-05 Journal: Frontiers in Microbiology [Category] update2024, [키워드] Lipid rafts protein trafficking Protein–protein interaction SARS-CoV-2 statins [DOI] 10.3389/fmicb.2023.1335458 PMC 바로가기 [Article Type] Microbiology Original Research
The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hostsarticle Published on 2023-06-302024-09-01 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] antimalarial compound cytoadherence Plasmodium falciparum protein trafficking protein translation [Article Type] article
A Syntenin Inhibitor Blocks Endosomal Entry of SARS-CoV-2 and a Panel of RNA VirusesArticle Published on 2022-10-062022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome Antiviral antivirals bind block cellular membrane Chikungunya CHIKV coronavirus dependent on develop domain endosomal endosomal entry Factor flavivirus Host HPV Infection inhibit inhibitor Interaction Panel peptide Peptide inhibitor Protein protein trafficking provide reduced regulate replicate RNA RNA viruses SARS-CoV-2 shown syntenin. target targeting virus [DOI] 10.3390/v14102202 PMC 바로가기
Labeling Strategies for Surface-Exposed Protein Visualization and Determination in Plasmodium falciparum Malariaarticle Published on 2022-06-302024-09-01 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] malaria Plasmodium falciparum protein labeling protein trafficking protein visualization Reporter of Insertion and Surface Exposure (RISE) surface-exposed protein surface-exposed protein determination [Article Type] article
Kinetic Tracking of Plasmodium falciparum Antigens on Infected Erythrocytes with a Novel Reporter of Protein Insertion and Surface ExposureArticle Published on 2022-06-282024-08-28 Journal: mBio [Category] 말라리아, [키워드] ion channels malaria membrane insertion NanoLuc nutrient uptake protein export protein trafficking
The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecturearticle Published on 2022-05-312024-09-01 Journal: Molecular Microbiology [Category] 말라리아, [키워드] blebs erythrocyte Invasion Plasmodium falciparum protein trafficking vacuole [Article Type] article
Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasion423 Published on 2022-02-112022-10-29 Journal: Proceedings of the National Academy of Sciences of [Category] COVID-19, SARS, [키워드] 40S 5′ UTR Antisense oligonucleotide antiviral immunity block bypassing C-terminal domain circumvent Concentration conserved COVID-19 COVID-19 pandemic Critical drug resistance effective therapy evade expressing Health highly pathogenic Host host protein human ACE2 infected cell inhibit interfere maintain mechanism Messenger RNA mRNA mRNA stability nonstructural protein 1 nucleic acid pathogenicity presenting PROTECT protein trafficking Replication SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2–infected mice sequence Significance suppress susceptible targeting the SARS-CoV-2 therapeutic therapeutic target transgenic mice translation translational unique Vaccines variants variants of SARS-CoV-2 Viral protein viral replication virulence virus [DOI] 10.1073/pnas.2117198119 PMC 바로가기 [Article Type] 423
PDZ-Containing Proteins Targeted by the ACE2 ReceptorCommunication Published on 2021-11-152022-10-28 Journal: Viruses [Category] COVID-19, [키워드] ACE2 benefit binding binding assay Brain C-terminal COVID-19 domain enzyme expressed Extracellular host cell host factors human epithelial cell in viral intensity Interaction involved main receptor membrane protein Modification motif N-terminal peptidase Neurological symptom neuronal neuronal cells organs PDZ domain Protein protein trafficking SARS-CoV-2 SARS-CoV-2 entry SNX27 specificity transmembrane trimeric spike type I virus entry [DOI] 10.3390/v13112281 PMC 바로가기 [Article Type] Communication