Collection and detection of SARS-CoV-2 in exhaled breath using face mask안면 마스크를 사용하여 호기에서 SARS-CoV-2 수집 및 감지Article Published on 2022-08-182022-09-11 Journal: PLoS ONE [Category] SARS, 치료기술, 치료제, [키워드] addition breath collected Collection Cross-infection electrostatic examined expected face Face mask Face masks Genes Mask Masks Molecular tests Nasopharyngeal swab Nasopharyngeal swab samples noninvasive nucleic acid ORF1 ORF1ab pandemic PCR PCR assay PCR assays PCR test PCR tests positive Prevent PROTECT protocol quantity RCA RdRP reduce RNA extraction Rolling circle amplification SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 tests significantly subjects target gene Target genes Transmission utility virus virus detection was performed was selected [DOI] 10.1371/journal.pone.0270765 PMC 바로가기 [Article Type] Article
A Method for Variant Agnostic Detection of SARS-CoV-2, Rapid Monitoring of Circulating Variants, and Early Detection of Emergent Variants Such as OmicronSARS-CoV-2의 변이 불가지론적 검출, 순환 변이체의 신속한 모니터링 및 오미크론과 같은 새로운 변이체의 조기 검출을 위한 방법Article Published on 2022-07-202022-09-11 Journal: Journal of Clinical Microbiology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] accelerate approach concerning COVID-19 Delta detect detection diagnostic test diagnostic tests effective Efficacy Genotype genotyping geographical distribution Health Organization healthcare in vitro in vitro diagnostics INDEL indels lab less Lineage marker monitoring mutations Next-generation sequencing NGS omicron polymorphism positive sample Prevalence prevalent public health quantity question raised Rapid reducing Reporting resources Responding retrospective reverse transcription PCR RT-PCR SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants sequence Sequencing significantly single-nucleotide SNPs Specific Strains transmission pattern transmission patterns utility Vaccines variant variants was determined WHO World Health Organization [DOI] 10.1128/jcm.00342-22 PMC 바로가기 [Article Type] Article
Monocytic-Myeloid Derived Suppressor Cells Suppress T-Cell Responses in Recovered SARS CoV2-Infected Individuals단핵구 골수 유래 억제 세포는 회복된 SARS CoV2에 감염된 개인의 T 세포 반응을 억제합니다Article Published on 2022-06-242022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, 치료법, 치료제, [키워드] adaptive immune responses Antigen arginase caused CD11b CD14 CD33 CD57 Cell characterized clinical recovery coronavirus disease Coronavirus disease 2019 correlated COVID-19 CX3CR1 CXCL1 CXCL2 cytokine production Cytokine storm Cytokines depleting dominant downregulated DQA1 DQB1 effector memory expansion Frequency function functional functions Gene Expression HLA-B HLA-DQA1 HLA-DQB1 HLA-DR Hyperinflammatory Hyperinflammatory response IL-6 IL1β immune immune activation immune responses individual individuals infected individual Infection membrane monocytic-myeloid derived suppressor cells mononuclear cell NLRP3 nucleocapsid pathway Pathway analysis Pathways PBMC PD1 peptide peptide pool peptide pools Peripheral blood Peripheral blood mononuclear cells plasma quantity recall recovered regulate remained response RNA-Seq ROS SARS Coronavirus SARS coronavirus 2 SARS CoV2 infection shown spike glycoprotein subset suppress suppresse suppressed suppressor T cell T cell response T cell responses T-cell T-cell responses target TGFβ transcriptional transcriptomic transcriptomic (RNA-Seq). Vaccine viral infection virus [DOI] 10.3389/fimmu.2022.894543 PMC 바로가기 [Article Type] Article
Evaluation of the safety and immunogenicity of different COVID-19 vaccine combinations in healthy individuals: study protocol for a randomized, subject-blinded, controlled phase 3 trial [PRIBIVAC]건강한 개인에서 다양한 COVID-19 백신 조합의 안전성 및 면역원성 평가: 무작위, 피험자 맹검, 대조 3상 시험을 위한 연구 프로토콜 [PRIBIVAC]Article Published on 2022-06-162022-09-11 Journal: Trials [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, [키워드] adverse event adverse events anti-SARS-CoV-2 antibodies antibody approval best blood sample Blood samples BNT162b2 boost booster booster dose booster vaccinations cellular Cellular immune response collected Combination Comprehensive control arm Controlled clinical trial CoronaVac country COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines demonstration different time point different time points dose Effectiveness Eligible participants Endpoint enrolment evade excluded group healthy Heterologous homologous host immunity humoral immune immune profiling immune response Immunity Immunocompromised immunogenicity Immunoglobulin immunoglobulins Inactivated vaccine Infection Intervention intervention arm Laboratory test Laboratory tests Local maintain mRNA mRNA vaccine mRNA-1273 omicron over parameters participant performed persistence phase Phase 3 phase 3 trial physical population immunity pregnant primary endpoint Probability quantity raising randomization Randomized Randomized controlled trial regimen Regulatory SARS-CoV-2 SARS-COV-2 infection Serious Adverse Event Serious Adverse Events Singapore Study protocol vaccination Vaccine vaccine availability vaccine booster vaccine candidate variants variants of concern volunteers wildtype [DOI] 10.1186/s13063-022-06345-2 PMC 바로가기 [Article Type] Article
Vaccines alone will not prevent COVID-19 outbreaks among migrant workers-the example of meat processing plants백신만으로는 이주노동자 사이의 코로나19 발병을 막을 수 없다(육가공공장의 예)Review Published on 2022-06-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 변종, [키워드] approach clinics Community country COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 transmission droplet employment equity Evidence example expelled Health health equity high risk highlight include increasingly Infection prevention mandatory Mandatory vaccination Meat processing plants migrant worker migrants omicron Outbreaks outcome outcomes overcome performed physically plant Population Prevent Prevention and control PROTECT quantity required respiratory rate respiratory rates risk SARS-CoV-2 variant SARS-CoV-2 viral sick Spread Support Universal vaccination Vaccine Vaccine hesitancy Vaccines Ventilation Viral transmission [DOI] 10.1016/j.cmi.2022.02.004 PMC 바로가기 [Article Type] Review
SMD-YOLO: An efficient and lightweight detection method for mask wearing status during the COVID-19 pandemicSMD-YOLO: COVID-19 전염병 동안 마스크 착용 상태에 대한 효율적이고 가벼운 감지 방법Article Published on 2022-06-012022-09-11 Journal: Computer methods and programs in biomedicine [Category] 치료기술, 치료제, [키워드] Accuracy Activation Algorithm average Clustering Combination compensated computer computer vision Convolution COVID-19 COVID-19 epidemic COVID-19 pandemic cross dataset Deep Learning Method demonstrated detection efficiency effective Effectiveness evaluated experiment face Face mask face mask detection Face masks feasible feature FLOPs functions greater hospitals IMPROVE increase information Mask mean average precision mechanism object object detection parameter Precision premise present Prevent provided quantity receptive field reduce reduced respiratory virus speed Spread status target YOLO YOLO. YOLOv4 YOLOv4-Tiny [DOI] 10.1016/j.cmpb.2022.106888 PMC 바로가기 [Article Type] Article
Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccineSARS-CoV-2 mRNA 백신 3차 접종 후 오미크론 반응성 B 세포 기억의 효율적인 회수Article Published on 2022-05-262022-09-11 Journal: Cell [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] added Alpha antibody Antibody titer Antibody titers Antigen B cell memory Beta booster Cell circulating antibodies circulating antibody correlated COVID-19 Delta dose efficient examined fold immune immune memory Immunity IMPROVE increase in limit memory B memory B cell memory B cells mRNA mRNA vaccination mRNA vaccine neutralizing antibody titers omicron Omicron variants quantity RBD-specific memory B cells recall remained response SARS-CoV-2 spike These data vaccination Vaccine variants variants of concern wild-type [DOI] 10.1016/j.cell.2022.04.009 PMC 바로가기 [Article Type] Article
Detection and quantification of SARS-CoV-2 RNA in wastewater influent in relation to reported COVID-19 incidence in Finland핀란드에서 보고된 COVID-19 발병률과 관련하여 폐수 유입수에서 SARS-CoV-2 RNA의 검출 및 정량화Article Published on 2022-05-152022-09-11 Journal: Water research [Category] COVID19(2023년), SARS, 치료기술, [키워드] amplified CDC changes in clinical testing Community sewage confirmed COVID-19 case coronavirus Coverage COVID-19 COVID-19 case COVID-19 cases COVID-19 incidence detect detection detection rate determined by Epidemiology exhibited Finnish FIVE followed by incidence incidence rate independent independent of Indicator individual less limit Linear regression Local Multiple Multiple linear regression National National surveillance Non-invasive nucleic acid nucleic acid extraction over Pandemics plant population level positive Probability public health quantification quantified quantity R 2 remained replicates reported required RNA RT-qPCR RT-qPCR assay SARS-CoV-2 SARS-CoV-2 RNA significantly more study period Surveillance tested the SARS-CoV-2 total population Treatment was determined Wastewater-based epidemiology [DOI] 10.1016/j.watres.2022.118220 PMC 바로가기 [Article Type] Article
Improved methods for the detection and quantification of SARS-CoV-2 RNA in wastewater폐수에서 SARS-CoV-2 RNA의 검출 및 정량화를 위한 개선된 방법Article Published on 2022-05-032022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] aluminum aluminum hydroxide buffer complexity Concentration confirmed cases coronavirus correlation COVID-19 pandemic detect enveloped virus epidemiological data genetic material glycine hydroxide Improved lack matrix mengovirus methodology N1 and N2 organic matter positive Precipitation problems produced quantification quantity reduction SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection selected targets virus wastewater [DOI] 10.1038/s41598-022-11187-8 PMC 바로가기 [Article Type] Article
Evaluation of saliva self-collection devices for SARS-CoV-2 diagnosticsSARS-CoV-2 진단을 위한 타액 자가 수집 장치 평가Article Published on 2022-03-252022-09-11 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, 치료법, [키워드] affected analyzed assistance bottleneck buffer Community condition COVID-19 pandemic current determined by diagnostic Diagnostic method diagnostic testing diagnostics evaluate evaluated expand funnel implementation incubated individual individuals Large-scale testing no significant difference Pathogens problems professionals profiles quantity respiratory pathogen Respiratory pathogens RNase P Safe Saliva SARS-CoV-2 SARS-CoV-2 nucleocapsid sensitivity significant difference Supply chain temperature were used [DOI] 10.1186/s12879-022-07285-7 PMC 바로가기 [Article Type] Article