Optimal balance of benefit versus risk for tafenoquine in the treatment of Plasmodium vivax malariaArticle Published on 2024-05-132024-08-29 Journal: Malaria Journal [Category] 말라리아, [키워드] Benefit–risk Plasmodium vivax malaria radical cure tafenoquine
Response to comment on ‘The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis’article Published on 2024-02-282024-09-01 Journal: eLife [Category] 말라리아, [키워드] Epidemiology global health haemolysis Human Infectious disease Microbiology Plasmodium vivax malaria radical cure tafenoquine [Article Type] article
Comment on ‘The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis’article Published on 2024-02-282024-09-01 Journal: eLife [Category] 말라리아, [키워드] Epidemiology global health haemolysis Human Infectious disease Microbiology Plasmodium vivax malaria radical cure tafenoquine [Article Type] article
Hypnozoite dynamics for Plasmodium vivax malaria: The epidemiological effects of radical curearticle Published on 2022-03-312024-09-01 Journal: Case Reports in Obstetrics and Gynecology [Category] 말라리아, [키워드] hypnozoite Infinite server queue Multiple infection radical cure Relapse vivax malaria [Article Type] article
Tafenoquine and its derivatives as inhibitors for the severe acute respiratory syndrome coronavirus 2중증 급성 호흡기 증후군 코로나바이러스 2에 대한 억제제로서의 타페노퀸 및 그 유도체Article Published on 2022-03-012022-09-11 Journal: The Journal of Biological Chemistry [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected antimalarial antimalarial drug approved catalysis catalytic caused complex Compound coronavirus COVID-19 crystal structure Cys145 derivative drug drug action Drug administration drug design Drug discovery effective food Food and Drug Administration identify infectibility Infection inhibit inhibited inhibitor library M pro main protease malaria maturation mutant pandemic peptide Plasmodium vivax Prophylaxis protease Protease activity radical cure rising SARS-CoV-2 SARS-CoV-2 main protease screened Serine serine 2 severe acute respiratory syndrome Coronavirus substrates tafenoquine the SARS-CoV-2 therapeutic therapeutic index therapeutic target TMPRSS2 transmembrane Treatment variants viral protease Viral protein virus entry [DOI] 10.1016/j.jbc.2022.101658 PMC 바로가기 [Article Type] Article
How radical is radical cure? Site-specific biases in clinical trials underestimate the effect of radical cure on Plasmodium vivax hypnozoites급진적 치료는 얼마나 급진적인가? 임상 시험에서의 장소 특정 편향은 Plasmodium vivax 하이프노조이트에 대한 급진적 치료의 효과를 과소평가한다.Research Published on 2021-12-202024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] bias clinical trials Plasmodium vivax radical cure [DOI] 10.1186/s12936-021-04017-1 PMC 바로가기 [Article Type] Research
Plasmodium vivax Latent Liver Stage Infection and Relapse: Biological Insights and New Experimental ToolsArticle Published on 2021-10-312024-09-10 Journal: Annu Rev Microbiol [Category] 말라리아, [키워드] hypnozoite malaria Plasmodium cynomolgi Plasmodium vivax radical cure Relapse sporozoite PMC 바로가기
Opening the policy blackbox: unravelling the process for changing national diagnostic and treatment guidelines for vivax malaria in seven countries정책 블랙박스 열기: 7개국에서 비박시 말라리아에 대한 국가 진단 및 치료 지침 변경 과정 해명하기Research Published on 2021-10-302024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] Malaria elimination Malaria health policy Plasmodium vivax malaria Policy pathways radical cure [DOI] 10.1186/s12936-021-03959-w PMC 바로가기 [Article Type] Research
Increased primaquine total dose prevents Plasmodium vivax relapses in patients with impaired CYP2D6 activity: report of three cases프리마퀸 총 용량 증가가 CYP2D6 활성이 저하된 환자에서 플라스모디움 비박스 재발을 예방한다: 세 가지 사례 보고Case Report Published on 2021-08-142024-08-08 Journal: Malaria Journal [Category] 말라리아, [키워드] CYP2D6 Plasmodium vivax primaquine radical cure relapses [DOI] 10.1186/s12936-021-03869-x PMC 바로가기 [Article Type] Case Report
The growing complexity of COVID-19 drug and vaccine candidates: challenges and critical transitionsCOVID-19 약물 및 백신 후보의 복잡성 증가: 도전과제 및 중요한 전환Review Published on 2021-02-012022-09-11 Journal: Journal of infection and public health [Category] 변종, 신약개발, 임상, 치료제, [키워드] affected approved Characteristics clinical trial Computational docking coronavirus COVID-19 Critical drug Drug repurposing drug therapy group health systems infecting Intervention life Mutation organism pandemic radical cure Research SARS-CoV-2 significantly higher therapy Transmissibility Trial Vaccine [DOI] 10.1016/j.jiph.2020.12.009 PMC 바로가기 [Article Type] Review