Evidence in decision-making in the context of COVID-19 in Latin AmericaResearch article Published on 2022-10-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 진단, [키워드] Analysis characterized Community Corticosteroids country COVID-19 COVID-19 pandemic Decision-making diagnostic test eight Evidence facilitate finding funding Grounding hydroxychloroquine/chloroquine identify International Intervention Ivermectin Latin Latin America limitation majority methodology mitigate National NPI NPIs objective outcome rapid response reported risk of infection systematic review Travel treat understanding Variation was used [DOI] 10.1016/j.lana.2022.100322 [Article Type] Research article
Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccineComparative Study Published on 2022-09-012022-10-06 Journal: EBioMedicine [Category] SARS, 변종, 진단, [키워드] antibody B.1.1.529 circulating COVID-19 case Efficacy elicit ENhance evaluated expressing foundation global public health hamster hamsters Immunity immunized Infection Intramural less Lineage mice Mutation naïve Neutralizing antibodies Neutralizing antibody titer omicron platform Population pre-existing immunity predicted Program PROTECT Protective provide rapid response replacing Replication reported Research respiratory tissue RNA RNA vaccine SARS-CoV-2 shown single dose Spread strain supported the SARS-CoV-2 Transmissibility vaccination Vaccine variant viral escape viral shedding viral spike protein Washington [DOI] 10.1016/j.ebiom.2022.104196 PMC 바로가기 [Article Type] Comparative Study
Epidemiological and clinical characteristics of the largest COVID-19 outbreak along the China-Myanmar border in Ruili City, Yunnan Province, ChinaArticle Published on 2022-08-232022-11-16 Journal: Frontiers in Public Health [Category] SARS, 변종, 유전자 메커니즘, [키워드] antibody breakthrough infections caused Characteristics China China-Myanmar border Chinese city Clinical characteristics collected Contact COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 vaccination COVID-19 vaccine cycle threshold death Delta delta variant Epidemics epidemiological greater IgM and IgG immune Infection land mechanism Mild moderate MOST occurred outbreak Patient rapid response reported Research risk SARS-CoV-2 SARS-CoV-2 Delta VOC Sequencing Transmission vaccinated against COVID-19 VoC were used [DOI] 10.3389/fpubh.2022.962214 PMC 바로가기
Speed and need: twin development challenges in rapid response for a SARS-CoV-2 antibody cocktail속도와 필요성: SARS-CoV-2 항체 칵테일에 대한 신속한 대응을 위한 두 가지 개발 과제Review Published on 2022-08-012022-09-12 Journal: Current opinion in biotechnology [Category] MERS, SARS, 비임상, 진단, [키워드] addressed antibody Cell culture Combined COVID-19 treatment Diseases example Genentech knowledge management monoclonal antibody monoclonal antibody treatment Patient Process provided purification rapid response Regeneron risk SARS-CoV-2 antibody selected speed timeline transfer Treatment urgency worldwide pandemic [DOI] 10.1016/j.copbio.2022.102715 PMC 바로가기 [Article Type] Review
The green tea catechin EGCG provides proof-of-concept for a pan-coronavirus attachment inhibitor녹차 카테킨 EGCG는 범 코로나바이러스 부착 억제제에 대한 개념 증명을 제공합니다Article Published on 2022-07-282022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Antiviral antiviral activity attachment block catechin caused Cell conserved coronavirus Coronavirus-2 Coronaviruses CoV CoV infection COVID-19 pandemic CoVs EGCG Endemic epigallocatechin epigallocatechin gallate epithelial cells gallate glycans green tea HCoV-OC43 Health heparan sulfate heparin highlight highly pathogenic CoVs Infection inhibitor inhibitors Lentiviral particle lentiviral particles Lung epithelial cells mechanism murine Prevent PROTECT Proteoglycan provide pseudotyped rapid response reduce remained required SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus shown Spike protein Spike proteins sulfate target cell Treatment Vaccine development virion binding virus [DOI] 10.1038/s41598-022-17088-0 PMC 바로가기 [Article Type] Article
Identification of potential pan-coronavirus therapies using a computational drug repurposing platform계산 약물 재검사 플랫폼을 사용한 잠재적 팬-코로나 바이러스 요법의 식별Article Published on 2022-07-012022-08-31 Journal: Methods (San Diego, Calif.) [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] acute respiratory syndrome approach approved drug approved drugs artificial Artificial neural network causative agent clinical trials Computational drug coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 datasets disease disease outbreaks drug Drug mechanism Drug repurposing drugs effective facilitate Human identification Infectious disease infectious disease outbreak information mechanism mechanism of action methodology novel Outbreaks pandemic Pathways platform PPI PPI network predicted protein-protein interaction rapid response Replication respiratory SARS SARS-CoV seriously ill patients Severe acute respiratory syndrome therapeutic therapy Treatment Validity virus replication Zoonotic coronavirus [DOI] 10.1016/j.ymeth.2021.11.002 PMC 바로가기 [Article Type] Article
Utilizing Electrochemical-Based Sensing Approaches for the Detection of SARS-CoV-2 in Clinical Samples: A Review임상 샘플에서 SARS-CoV-2 검출을 위한 전기화학 기반 감지 접근 방식 활용: 검토Review Published on 2022-06-292022-09-11 Journal: Biosensors [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 advance Blood clinical clinical samples coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 detection diagnose diagnostic diagnostic methods diagnostic tests diagnostics early treatment electrochemical biosensor employment equipment healthcare worker Healthcare workers in viral individuals infected individuals Infection Isolation limit limitations microfluidic electrochemical devices miniaturised electrochemical sensor Nasopharyngeal swab operation platform POC point of care point of care (PoC) rapid response readiness respiratory review Saliva SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus simplicity Spread standard diagnostic test standard diagnostic tests transducing Viral [DOI] 10.3390/bios12070473 PMC 바로가기 [Article Type] Review
SperoPredictor: An Integrated Machine Learning and Molecular Docking-Based Drug Repurposing Framework With Use Case of COVID-19SPEROPDICTOR : COVID-19의 사용 사례와 함께 통합 된 기계 학습 및 분자 도킹 기반 약물 재검사 프레임 워크Article Published on 2022-06-162022-08-31 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, 신약개발, [키워드] Accuracy association candidate clinically collected contagious contagious disease coronavirus costly COVID-19 data analytics database databases dataset de novo death disease drug drug candidate Drug discovery Drug repurposing effective effort Extensive FDA approval FDA-approved drug FDA-approved drugs feature Features followed by forest framework generic drug Gradient Host host proteomes human host indicated inefficient machine learning molecular docking pandemic Pandemics platform predicted proteome Random forest rapid response reduce repurposing Research resulting SARS Coronavirus SARS coronavirus 2 SARS-CoV-2 Spread spread of COVID-19 systematic review Threats Traditional tree trees variant [DOI] 10.3389/fpubh.2022.902123 PMC 바로가기 [Article Type] Article
Accelerated waning of immunity to SARS-CoV-2 mRNA vaccines in patients with immune-mediated inflammatory diseases면역 매개 염증성 질환 환자에서 SARS-CoV-2 mRNA 백신에 대한 면역 약화 가속화Observational Study Published on 2022-06-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단, 치료기술, [키워드] Adaptive immunity Adult patients All participants ankylosing spondylitis anti-TNF Arthritis attrition Autoimmune diseases azathioprine COVID-19 COVID-19 vaccination declining disease donation dose Efficacy examined force greater healthy control healthy controls Immune-mediated inflammatory disease Immune-mediated inflammatory diseases Immunity immunogenicity immunology Immunosuppressant immunosuppressants immunosuppressive therapies Immunotherapy Inflammatory bowel disease Inflammatory diseases information Juan methotrexate mRNA vaccine neutralization Observational cohort study omicron Participants Patient rapid response rheumatoid arthritis SARS-CoV-2 SARS-CoV-2 variants Speck spondylitis subjects Support T cell T cell response Task Force Treatment undetectable Vaccine variants variants of concern [DOI] 10.1172/jci.insight.159721 PMC 바로가기 [Article Type] Observational Study
Agility and Sustainability: A Qualitative Evaluation of COVID-19 Non-pharmaceutical Interventions in the UK Logistics SectorArticle Published on 2022-06-012023-07-09 Journal: Frontiers in Public Health [Category] COVID19(2023년), [키워드] COVID-19 delivery workers logistics sector Non-pharmaceutical interventions rapid response [DOI] 10.3389/fpubh.2022.864506 PMC 바로가기