Advanced integration of 2DCNN-GRU model for accurate identification of shockable life-threatening cardiac arrhythmias: a deep learning approachPhysiology Original Research Published on 2024-07-122024-09-05 Journal: Frontiers in Physiology [Category] update2024, [키워드] dangerous arrhythmias data synthesis deep learning networks Recognition scalogram [DOI] 10.3389/fphys.2024.1429161 PMC 바로가기 [Article Type] Physiology Original Research
Exploring the anticomplement components from Fagopyrum dibotrys for the treatment of H1N1-induced acute lung injury by UPLC-Triple-TOF-MS/MSArticle Published on 2023-01-202023-06-24 Journal: Journal of pharmaceutical and biomedical analysis [Category] 신종인플루엔자, [키워드] complement system Fagopyrum dibotrys (D. Don) procyanidins Recognition Structure-activity relationship [DOI] 10.1016/j.jpba.2022.115158
On the Recognition of Natural Substrate CTP and Endogenous Inhibitor ddhCTP of SARS-CoV-2 RNA-Dependent RNA Polymerase: A Molecular Dynamics StudyArticle Published on 2022-10-242022-11-15 Journal: Journal of Chemical Information and Modeling [Category] COVID19(2023년), SARS, 치료제, [키워드] absence affecting Antiviral computational method COVID-19 outbreak Cryo-electron microscopy cytidine Dynamics endogenous enzyme help implication in silico information inhibitor inhibitory innate immune response investigated MD simulation mechanism molecular molecular mechanism multiple mutation natural novel coronavirus SARS-CoV-2 nucleotide pandemic Protein RdRP RdRp active site Recognition responsible RNA RNA sequence RNA-dependent RNA polymerase SARS-CoV-2 substrate viral replication virus [DOI] 10.1021/acs.jcim.2c01002 PMC 바로가기
Deep Transfer Learning for COVID-19 Detection and Lesion Recognition Using Chest CT ImagesArticle Published on 2022-10-152022-11-15 Journal: Computational and Mathematical Methods in Medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy addition AUC automated can be used caused Chest CT image Chest CT images Chest CT scans CNN Complete Computed tomography coronavirus disease COVID-19 COVID-19 diagnosis CT-scan datasets death deep deep learning detection diagnose Diagnosis Diagnostic method false discovery rate FDR global pandemic heatmap highlight identify Image IMPROVE introduced learning lesion plague radiologist Recognition sensitivity shown specificity starting time-consuming transformer [DOI] 10.1155/2022/4509394 PMC 바로가기
Deep learning techniques for detecting and recognizing face masks: A surveyArticle Published on 2022-09-262022-11-15 Journal: Frontiers in Public Health [Category] SARS, 치료기술, [키워드] adhere Algorithm carried change conducted Convolutional neural network crowd monitoring death deep deep learning detect effective face Face mask feature help individuals lockdown Mask measure OFR outbreak public health Recognition recognizing reduce Research Spread the disease transfer transfer learning Vaccine virus wear face mask [DOI] 10.3389/fpubh.2022.955332 PMC 바로가기
Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infectionArticle Published on 2022-09-232022-11-16 Journal: Nature Communications [Category] SARS, 변종, [키워드] accumulation acute respiratory syndrome adaptive affected antibody B cell CD8 T cell chronic infection circulating convalescent Coronavirus-2 Donor Effect epitope Epitopes Evolution homoplasy humoral identify Immunocompromised patient immunodeficiency Impact Infection lineages lymphoma mutant Mutation mutations neutralization Patient peptide plasma-mediated Recognition reduced Region resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 mutations SARS-CoV-2 sequence the spike protein Vaccine design [DOI] 10.1038/s41467-022-32772-5 PMC 바로가기
Non-enzymatic signal amplification-powered point-of-care SERS sensor for rapid and ultra-sensitive assay of SARS-CoV-2 RNASARS-CoV-2 RNA의 신속하고 초민감한 분석을 위한 비효소 신호 증폭 기반 현장 진료 SERS 센서Article Published on 2022-09-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification carried ChIP clinical samples Combination COVID-19 diagnostic DNA Early detection expected generate Nuclease nucleic acids other respiratory virus Other respiratory viruses point-of-care Prevention and control probe Raman spectroscopy Recognition respiratory viruses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA sensitivity SERS silver target Target recycling signal amplification. ultra-sensitive assay viral nucleic acids virus infection [DOI] 10.1016/j.bios.2022.114379 PMC 바로가기 [Article Type] Article
Epigenetics at the Intersection of COVID-19 Risk and Environmental Chemical ExposuresCOVID-19 위험과 환경 화학 물질 노출의 교차점에서의 후성 유전학Review Published on 2022-09-012022-09-11 Journal: Current environmental health reports [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Alter among others Chemical contaminant COVID-19 COVID-19 susceptibility disease disrupting Drawing Endocrine Environmental chemicals Epigenetic epigenetic modification epigenetics Evidence exposure host antiviral responses host response immune pathway immune system Immunity Immunologic memory immunomodulation implicated include Infectious disease Inflammation Intersection involved mechanism memory Modification molecular mechanism Numerous Pathways recent Recognition Regulation risk SARS-CoV-2 SARS-CoV-2 virus severe COVID-19 severity Specific susceptibility the SARS-CoV-2 virus viral entry [DOI] 10.1007/s40572-022-00353-9 PMC 바로가기 [Article Type] Review
Butein as a potential binder of human ACE2 receptor for interfering with SARS-CoV-2 entry: a computer-aided analysisSARS-CoV-2 진입을 방해하기 위한 인간 ACE2 수용체의 잠재적 결합제로서의 부테인: 컴퓨터 지원 분석Article Published on 2022-08-242022-09-11 Journal: Journal of molecular modeling [Category] SARS, 치료제, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin antiviral activity atomic level Butein clinical trials Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 demonstrated dietary supplement drug candidate effective examined hACE-2 hACE2 hACE2 receptor herbal compound herbal compounds host cell host cells human ACE2 receptor human Angiotensin-converting enzyme In silico methods Infection infections Interaction interfere molecular molecular docking molecular dynamics Molecular modeling natural natural products pathogen Pathogens physicochemical Phytoconstituents profile receptor Recognition researcher SARS-CoV-2 screened selected severe acute respiratory syndrome Coronavirus shown Spike protein subset target protein therapeutic these compound these compounds viral entry viral particle Viral particles zoonotic [DOI] 10.1007/s00894-022-05270-0 PMC 바로가기 [Article Type] Article
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variantmRNA 부스터 백신 접종은 SARS-CoV-2 오미크론 변이체로부터 나이든 마우스를 보호합니다Article Published on 2022-08-062022-09-11 Journal: Communications Biology [Category] SARS, 변종, 진단, [키워드] Adults Analysis benefit BNT162b2 booster booster dose booster vaccination cell-mediated response Cell-mediated responses Effect Efficacy elicit ENhance evade evaluate Evidence evidence of humoral Immunity immunization Lung infection mice mRNA mRNA BNT162b2 mRNA vaccine murine Neutralizing activity Neutralizing antibodies neutralizing antibody Older Older adults older population omicron PROTECT provide provided Recognition regimen risk SARS-CoV-2 SARS-CoV-2 variants severe disease sterilizing immunity the SARS-CoV-2 Vaccine Vaccine-induced immunity variant variants while [DOI] 10.1038/s42003-022-03765-3 PMC 바로가기 [Article Type] Article