Detailed role of mesenchymal stem cell (MSC)-derived exosome therapy in cardiac diseasesReview Article Published on 2024-03-252024-09-05 Journal: EXCLI Journal [Category] update2024, [키워드] cardiac diseases Exosome mesenchymal stem cell (MSC) regeneration Treatment [DOI] 10.17179/excli2023-6538 PMC 바로가기 [Article Type] Review Article
Single-cell division tracing and transcriptomics reveal cell types and differentiation paths in the regenerating lungArticle Published on 2024-03-122024-09-05 Journal: Nature Communications [Category] update2024, [키워드] cell division regeneration Respiratory tract diseases RNA sequencing transcriptomics [DOI] 10.1038/s41467-024-46469-4 PMC 바로가기 [Article Type] Article
Clinical applications of stem cell-derived exosomesReview Article Published on 2024-01-122024-09-05 Journal: Signal Transduction and Targeted Therapy [Category] update2024, [키워드] Diseases Preclinical research regeneration [DOI] 10.1038/s41392-023-01704-0 PMC 바로가기 [Article Type] Review Article
The Plastic Interplay between Lung Regeneration Phenomena and Fibrotic Evolution: Current Challenges and Novel Therapeutic PerspectivesReview Published on 2023-12-312024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] fibrosis Mesenchymal stem cells regeneration [DOI] 10.3390/ijms25010547 PMC 바로가기 [Article Type] Review
Macro, Micro, and Nano-Inspired Bioactive Polymeric Biomaterials in Therapeutic, and Regenerative Orofacial ApplicationsReview Published on 2023-09-272024-09-05 Journal: Drug design, development and therapy [Category] update2024, [키워드] dental Maxillofacial oral polymers regeneration [DOI] 10.2147/DDDT.S419361 PMC 바로가기 [Article Type] Review
Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lungarticle Published on 2023-09-092024-09-05 Journal: NPJ Regenerative Medicine [Category] update2024, [키워드] regeneration Stem-cell differentiation Stem-cell niche [DOI] 10.1038/s41536-023-00325-z PMC 바로가기 [Article Type] article
Mycobacterium leprae induces Schwann cell proliferation and migration in a denervated milieu following intracutaneous excision axotomy in nine-banded armadillosarticle Published on 2022-06-302024-09-01 Journal: Arq Fac Hig Saude Publica Univ Sao Paulo [Category] 한센병, [키워드] armadillos Axotomy Epidermal nerve Mycobacterium leprae p75 regeneration Schwann cells skin [Article Type] article
Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations폐 내피 세포의 단일 세포 전사체 프로파일링은 동적 염증 및 재생 하위 집단을 식별합니다Article Published on 2022-06-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), SARS, 신종인플루엔자, 유전자 메커니즘, [키워드] Activation Bacterial infections baseline Cell Clustering defined demonstrated division endothelial endothelial cells Endothelium expression Gene Expression H1N1 H1N1 influenza H1N1 influenza virus heterogeneity identify immune response gene immune response genes increased expression infected with SARS-CoV-2 Infectious disease Inflammatory inflammatory lung injury inflammatory signaling Influenza Injury labor limit LPS lung lung endothelial Lung injury MHC gene MHC genes murine organ overexpression Pathway analysis performed phenotypic prevented proliferative promote Pulmonology regeneration regenerative respond Seurat single-cell single-cell RNA-seq Sox17 subpopulation targeted therapy transcriptomic Vascular vascular bed vascular endothelial cell vascular endothelial cells virus [DOI] 10.1172/jci.insight.158079 PMC 바로가기 [Article Type] Article
Human placenta-derived amniotic epithelial cells as a new therapeutic hope for COVID-19-associated acute respiratory distress syndrome (ARDS) and systemic inflammationCOVID-19 관련 급성 호흡 곤란 증후군(ARDS) 및 전신 염증에 대한 새로운 치료 희망으로서의 인간 태반 유래 양막 상피 세포Review Published on 2022-03-252022-09-11 Journal: Stem Cell Research & Therapy [Category] SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus aldosterone alveolar fluid clearance amniotic Amniotic membrane angiotensin ARDS cause Cell complications complications of COVID-19 consequence Consequences coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 damaged death drug delivery system Efficacy epithelial cell epithelial cells Epithelial stem cells Exosome Exosomes feature fibrosis hAEC Human immune system immunomodulation immunomodulatory effect immunomodulatory effects mechanism membrane multi-organ failure organ organs Prevent question reaction reduce regeneration regenerative medicine Regulation Renin renin-angiotensin-aldosterone system respiratory distress SARS-CoV-2 serious complication severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 stem cells suggested syndrome systemic inflammation therapeutic Therapeutic approach therapeutic option These cells thrombotic Thrombotic events viral variant [DOI] 10.1186/s13287-022-02794-3 PMC 바로가기 [Article Type] Review
Inhaled Placental Mesenchymal Stromal Cell Secretome from Two- and Three-Dimensional Cell Cultures Promotes Survival and Regeneration in Acute Lung Injury Model in Mice2차원 및 3차원 세포 배양에서 흡입된 태반 중간엽 간질 세포 Secretome은 마우스의 급성 폐 손상 모델에서 생존 및 재생을 촉진합니다Article Published on 2022-03-222022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 유전자 메커니즘, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration adult stem cells ALI model ARDS Cell cell spheroids cell-free therapy content coronavirus COVID-19 COVID-19 pandemic cultivation damaged death effective Effectiveness exhibited Extracellular Extracellular vesicles FIBRIN fibroblast healthcare histological immunomodulating in some Inflammatory Inflammatory diseases inhalation Inhaled investigated lung Lung inflammation Lung injury lung surfactant lung tissue Lungs management Measures mice Model morbidity and mortality Mortality Patient placental potential therapy problem proteomic regeneration regenerative respiratory distress Respiratory distress syndrome restored SARS-CoV-2 Secretome severe acute respiratory syndrome Coronavirus severe pneumonia stromal cell surfactant survival syndrome Taking therapeutic tissue regeneration [DOI] 10.3390/ijms23073417 PMC 바로가기 [Article Type] Article